Biologically Active Substance
sarcosine Audio
sar·co·sine [ sahr-kuh-seen, -sin ]
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to sarcosine:
  • Aminoacid occurring as an intermediate in the metabolism of choline in the kidney and liver.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • An amino acid intermediate in the metabolism of choline.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An amino acid that is an intermediate and byproduct in glycine synthesis and degradation with potential anti-depressant and anti-schizophrenic activities. Sarcosine is a product of dietary consumption of choline and creatine and is rapidly converted into glycine. Oral administration of sarcosine with certain antipsychotics may cause increased glycine concentration in the brain, which may lead to increased NMDA receptor activation and a reduction in symptoms.
    NCI
    U.S. National Cancer Institute, 2021
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