Biologically Active Substance
serpin
Subclass of:
Serine Proteinase Inhibitors; Proteins; Peptides
Definitions related to serpins:
  • Irreversible serine proteinase inhibitors that exert their action on peptidases. Serpins can be localized inside, or outside of the cell, and are found in all groups of organisms with the exception of fungi. In human plasma, serpins represent approximately 2% of the total protein present.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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