Pharmacologic Substance
sevoflurane
Brand Names:
Petrem; SevoFlo; Sevosol; Sojourn; Ultane
Effect:
Decreased Medullary Respiratory Drive; General Anesthesia; Vasodilation
May Prevent:
Pain
May Treat:
Pain
More Information:
Definitions related to sevoflurane:
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A fluorinated isopropyl ether with general anesthetic property. Although the mechanism of action has not been fully elucidated, sevoflurane may act by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, and/or alter ionic conductance following receptor activation by a neurotransmitter. Sevoflurane may also interact directly with lipid matrix of neuronal membranes, thereby affecting gating properties of ion channels. In addition, this agent may activate gamma-aminobutyric acid (GABA) receptors hyperpolarizing cell membranes. This results in a general anesthetic effect, a decrease in myocardial contractility and mean arterial pressure as well as an increased respiratory rate.NCI ThesaurusU.S. National Cancer Institute, 2021
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A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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