Hormone
sincalide
Brand Names:
Kinevac
Effect:
Bile Secretion Volume Alteration; Decreased Esophageal Muscle Tone; Increased Gallbladder Tone; Inhibition Gastric Mucous Secretion; Stimulation Pancreatic Enzymatic Secretion
More Information:
Definitions related to sincalide:
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A synthetic C-terminal octapeptide identical to the sequences of the endogenous cholecystokinin hormone. Mimic action of cholecystokinin, sincalide induces gallbladder smooth muscle contraction directly, thereby reducing gallbladder size, inducing bile evacuation, and secretion of pancreatic enzymes. In addition, this agent decreases esophageal sphincter tone and delays gastric emptying via cholinergic signaling.NCI ThesaurusU.S. National Cancer Institute, 2021
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An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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