Immunologic Factor
siplizumab
[ sip-lih-zoo-mab ]
Definitions related to siplizumab:
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A humanized monoclonal immunoglobulin G1 antibody with potential antineoplastic activity. Siplizumab binds to CD2, a specific receptor found in T cells and NK cells, thereby triggering a host immune response that results in lysis of CD2+ cells, selective suppression of the immune system, and control of activated T cell growth.NCI ThesaurusU.S. National Cancer Institute, 2021
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A monoclonal antibody that is being studied in the treatment of certain lymphoproliferative disorders and psoriasis.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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