Congenital Abnormality
sirenomelia
Definitions related to sirenomelia:
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A developmental defect in which the legs are fused together.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A disorder characterized by the malformation of the legs into a single lower limb.NCI ThesaurusU.S. National Cancer Institute, 2021
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Any of several degrees of side-to-side fusion of lower extremities and concomitant midline reduction of the pelvis. Soft tissues and long bones, lower paw (feet), and viscera of the pelvis tend to be reduced or absent; anus and external genitalia are often absent. (Makris S, Solomon HM, Clark R, Shiota K, Barbellion S, Buschmann J, Ema M, Fujiwara M, Grote K, Hazelden KP, Hew KW, Horimoto M, Ooshima Y, Parkinson M, Wise LD. Terminology of developmental abnormalities in common laboratory mammals (Version 2). Part B. Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):227-327.)CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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Sirenomelia is a birth defect in which affected infants are born with a single lower extremity or with two legs that are fused together. The symptoms and physical findings associated with the condition vary greatly among affected individuals and may include malformations of the spine and skeletal system (commonly with vertebrae either...National Center for Advancing Translational Sciences
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