Pharmacologic Substance
sizofiran
Subclass of:
beta-Glucans
Definitions related to sizofiran:
  • A beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A soluble beta-D-glucan produced by the Basidiomycetes fungus, Schizophyllum commune Fries, with potential immunomodulating and antitumor activities. Although sizofiran's exact mechanism of action has yet to be fully elucidated, this agent appears to stimulate the immune system by increasing cytokine production, activating macrophages and enhancing the activity of polymorphonuclear leukocytes (PML) and natural killer (NK) cells.
    NCI
    U.S. National Cancer Institute, 2021
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