Pharmacologic Substance
squalamine lactate Audio
squal·a·mine lac·tate [ skwah-luh-meen lak-tayt ]
Definitions related to squalamine lactate:
  • A drug that belongs to the family of drugs called angiogenesis inhibitors. It prevents the growth of new blood vessels into a solid tumor.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • The lactate salt form of squalamine, an aminosterol isolated from tissues of the dogfish shark Squalus acanthias. Possessing anti-angiogenic properties, squalamine inhibits the sodium-hydrogen exchanger NHE3, resulting in suppression of endothelial cell proliferation and migration. This agent also has broad-spectrum antimicrobial properties. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
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