Pharmacologic Substance
tandutinib Audio
[ tan-doo-tih-nib ]
Definitions related to tandutinib:
  • A piperazinyl quinazoline receptor tyrosine kinase inhibitor with antineoplastic activity. Tandutinib inhibits the autophosphorylation of FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGF (platelet-derived growth factor) receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis.
    NCI
    U.S. National Cancer Institute, 2021
  • A substance being studied in the treatment of some types of cancer. It may stop cancer cell growth by blocking certain enzymes. It may also prevent the growth of new blood vessels that tumors need to grow. It is a type of tyrosine kinase inhibitor and a type of antiangiogenesis agent.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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