Pharmacologic Substance
tanomastat
Definitions related to tanomastat:
  • A biphenyl matrix metalloproteinase (MMP) inhibitor (MMPI) with potential antineoplastic activity. Tanomastat inhibits MMP-2, MMP-3, and MMP-9, inhibiting extracellular matrix degradation and potentially inhibiting angiogenesis, tumor growth and invasion, and metastasis. MMPs consist of at least 18 zinc-containing endo-proteinases that are capable of degrading collagen and proteoglycan.
    NCI
    U.S. National Cancer Institute, 2021
  • An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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