Pharmacologic Substance
tazarotene
[ ta-zar-oh-teen ]
Brand Names:
Arazlo; Avage; Duobrii; Fabior; Tazorac
Effect:
Cellular Division Phase Alteration; Cellular Growth Phase Arrest; Decreased Immunologically Active Molecule Activity; Decreased Transcription to RNA
May Treat:
Acne Vulgaris;
Psoriasis
More Information:
Definitions related to tazarotene:
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A drug used on the skin to treat several skin conditions. It is also being studied in the treatment of basal cell skin cancer and basal cell nevus syndrome. Tazarotene is related to vitamin A and is made in the laboratory. It turns on a gene that may help stop the growth of skin cancer cells. Tazarotene is a type of synthetic retinoid.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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