Pharmacologic Substance
tetradecanoylphorbol acetate Audio
[ teh-truh-deh-kuh-noyl-for-bol a-seh-tayt ]
Subclass of:
Phorbol Esters
Definitions related to tetradecanoylphorbol acetate:
  • A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • A substance being studied in the treatment of leukemias and lymphomas. It is also being studied in the treatment of other types of cancer. Tetradecanoylphorbol acetate affects many cell actions and may cause tumor cells to die. It is a type of phorbol ester.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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