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Related terms:
afibrinogenemia
thrombocytopathy
hemophilia B
hemophilia A
hemorrhagic disorder
thrombocytopenia
vitamin k deficiency
Wiskott-Aldrich syndrome
Hermanski-Pudlak syndrome
Disease or Syndrome
thrombasthenia
Subclass of:
Blood Coagulation Disorders, Inherited; Blood Platelet Disorders; Hemorrhagic Disorders
Definitions related to thrombasthenia:
  • A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Platelet abnormality characterized by defective clot formation, impaired aggregation, and prolonged bleeding time; other manifestations include nosebleeds, inappropriate bruising, and excessive bleeding.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • (glanzmann thrombasthenia) A rare, autosomal recessive inherited and less frequently acquired platelet disorder. It is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex. It leads to defective platelet aggregation, resulting in bleeding.
    NCI
    U.S. National Cancer Institute, 2021
  • (glanzmann thrombasthenia) A rare, autosomal recessive inherited, and less frequently acquired, platelet disorder that is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex, which leads to defective platelet aggregation, resulting in bleeding.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • Glanzmann thrombasthenia (GT) is a rare inherited blood clotting disorder that is present at birth. It is characterized by the impaired function of specialized blood cells, called platelets, that are essential for proper blood clotting. Signs and symptoms vary greatly from person to person. Symptoms usually include abnormal bleeding,...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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