Disease or Syndrome
thrombasthenia
Subclass of:
Blood Coagulation Disorders, Inherited;
Blood Platelet Disorders;
Hemorrhagic Disorders
Definitions related to thrombasthenia:
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A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Platelet abnormality characterized by defective clot formation, impaired aggregation, and prolonged bleeding time; other manifestations include nosebleeds, inappropriate bruising, and excessive bleeding.CRISP ThesaurusNational Institutes of Health, 2006
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(glanzmann thrombasthenia) A rare, autosomal recessive inherited and less frequently acquired platelet disorder. It is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex. It leads to defective platelet aggregation, resulting in bleeding.NCI ThesaurusU.S. National Cancer Institute, 2021
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(glanzmann thrombasthenia) A rare, autosomal recessive inherited, and less frequently acquired, platelet disorder that is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex, which leads to defective platelet aggregation, resulting in bleeding.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Glanzmann thrombasthenia (GT) is a rare inherited blood clotting disorder that is present at birth. It is characterized by the impaired function of specialized blood cells, called platelets, that are essential for proper blood clotting. Signs and symptoms vary greatly from person to person. Symptoms usually include abnormal bleeding,...National Center for Advancing Translational Sciences
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