Pharmacologic Substance
toremifene
Brand Names:
Fareston
Effect:
Decreased DNA Replication; Decreased Ovarian Estrogen Secretion
May Treat:
Breast Neoplasms; Neoplasms, Hormone-Dependent
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to toremifene:
  • A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An anticancer drug that belongs to the family of drugs called antiestrogens. Toremifene blocks the effect of the hormone estrogen in the body. It may help control some cancers from growing, and it may delay or reduce the risk of cancer recurrence.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.