Pharmacologic Substance
tranexamic acid
Brand Names:
Cyklokapron; Lysteda
Effect:
Decreased Fibrinolysis
May Prevent:
Oral Hemorrhage
May Treat:
Blood Coagulation Disorders, Inherited;
Subarachnoid Hemorrhage
More Information:
Definitions related to tranexamic acid:
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A synthetic derivative of the amino acid lysine with antifibrinolytic activity. With strong affinity for the five lysine-binding sites of plasminogen, tranexamic acid competitively inhibits the activation of plasminogen to plasmin, resulting in inhibition of fibrinolysis; at higher concentrations, this agent noncompetitively inhibits plasmin. This agent has a longer half-life, is approximately ten times more potent, and is less toxic than aminocaproic acid, which possesses similar mechanisms of action.NCI ThesaurusU.S. National Cancer Institute, 2021
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Antifibrinolytic hemostatic used in severe hemorrhage.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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