Pharmacologic Substance
triamcinolone acetonide
Effect:
Carbohydrate Metabolism Alteration; Decreased Capillary Permeability; Decreased Cytokine Activity; Decreased Fibroblast Migration; Decreased Glucocorticoid Secretion; Decreased Leukotriene Activity; Decreased Polymorphonuclear Leukocyte Migration; Decreased Prostaglandin Activity; Decreased Protein Synthesis; Decreased Thromboxane Activity; Lipid Metabolism Alteration; Lysosomal Function Alteration
May Prevent:
Arthritis, Gouty; Arthritis, Rheumatoid; Asthma
May Treat:
Adrenal Insufficiency;
Anemia, Hemolytic;
Berylliosis;
Bronchial Spasm;
Colitis, Ulcerative;
Dermatitis Herpetiformis;
Dermatitis, Atopic;
Erythema Multiforme;
Facial Dermatoses;
Foot Dermatoses;
Hand Dermatoses;
Hypercalcemia;
Inflammation;
Leg Dermatoses;
Lupus Erythematosus, Systemic;
Multiple Sclerosis;
Nephrotic Syndrome;
Pemphigus;
Rheumatic Diseases;
Rhinitis, Allergic, Perennial;
Scalp Dermatoses;
Serum Sickness;
Spondylitis, Ankylosing;
Synovitis;
Thyroiditis;
Tuberculosis, Pulmonary;
Uveitis
More Information:
Definitions related to triamcinolone acetonide:
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An esterified form of TRIAMCINOLONE. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.NCI ThesaurusU.S. National Cancer Institute, 2021
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