Antibiotic
valinomycin
[ val-uh-noh-mahy-sin ]
Subclass of:
Depsipeptides
Definitions related to valinomycin:
  • A cyclic depsipeptide isolated from the bacterium Streptomyces fulvissimus. As a potassium-specific ionophore, mould element causes loss of mitochondrial membrane potential, thereby initiating cellular apoptosis. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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