Pharmacologic Substance
valspodar
Definitions related to valspodar:
  • A substance that is being studied for its ability to prevent or overcome the resistance of tumor cells to some anticancer drugs. It belongs to the family of drugs called cyclosporine analogs.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • An analogue of cyclosporin-A. Valspodar inhibits p-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug-resistant tumor cells. This agent also induces caspase-mediated apoptosis. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
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