Pharmacologic Substance
verteporfin
Brand Names:
Visudyne
Effect:
Decreased Endothelial Proliferation; Increased Endothelial Coagulation Activity; Increased Platelet Aggregation; Photosensitizing Activity
May Treat:
Choroidal Neovascularization
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to verteporfin:
  • A benzoporphyrin derivative that is used in PHOTOCHEMOTHERAPY to treat wet type MACULAR DEGENERATION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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