Biologically Active Substance
wortmannin
Subclass of:
Androstadienes
Definitions related to wortmannin:
  • A potent fungal metabolite isolated from Penicillium wortmannin that selectively inhibits phosphatidylinositol 3-kinase and affects the signal transduction pathway. (NCI)
    NCI
    U.S. National Cancer Institute, 2021
  • An androstadiene metabolite produced by the fungi PENICILLIUM funiculosum that inhibits PHOSPHATIDYLINOSITOL-3-KINASES and alloantigen-specific activation of T-LYMPHOCYTES in human tumor cell lines. It is widely used in CELL BIOLOGY research and has broad therapeutic potential.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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