Pharmacologic Substance
zibotentan
Definitions related to zibotentan:
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A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called endothelin-receptor antagonists.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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An orally available selective antagonist of the endothelin-A (ET-A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation.NCI ThesaurusU.S. National Cancer Institute, 2021
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