Pharmacologic Substance
zileuton
[ zy-loo-tin ]
Brand Names:
Zyflo
Effect:
Bronchodilation; Decreased Capillary Permeability; Decreased Cellular Migration; Decreased Leukotriene Production
May Prevent:
Asthma
May Treat:
Asthma
More Information:
Definitions related to zileuton:
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A substance that is used to prevent asthma symptoms and that is being studied in the prevention of lung cancer. It belongs to the family of drugs called leukotriene blockers.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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