cryoglobulin - Definition

Immunologic Factor

cryoglobulin

cry·o·glob·u·lin

Subclass of:

Paraproteins

Etymology:

Greek kryos = frost, diminutive of Latin globus = a ball
Descriptive name for proteins precipitating from cooled serum.

Definitions related to cryoglobulins:

Aberrant plasma proteins seen in multiple myeloma that precipitate, gel or crystallize at low temperatures and redissolve upon reaching body temperature.

CRISP Thesaurus

National Institutes of Health, 2006

An abnormal plasma protein that precipitates within the microvasculature on exposure to cold; microvasculature effects of cryoglobulinemia may result in restricted tissue blood flow, tissue hypoxia, and tissue necrosis.

NCI Thesaurus

U.S. National Cancer Institute, 2021

Abnormal immunoglobulins, especially IGG or IGM, that precipitate spontaneously when SERUM is cooled below 37 degrees Celsius. It is characteristic of CRYOGLOBULINEMIA.

NLM Medical Subject Headings

U.S. National Library of Medicine, 2021

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