Biologically Active Substance
tau protein
tau pro·tein
Subclass of:
Microtubule-Associated Proteins
Definitions related to tau proteins:
  • Family of structural proteins of microtubules which serve to crosslink and therefore stabilize tubulin chains.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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