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The International Journal of... 2021To conduct a systematic review to evaluate the influence of materials and surfaces used for dental implant abutments on the proliferation of human gingival fibroblasts.
PURPOSE
To conduct a systematic review to evaluate the influence of materials and surfaces used for dental implant abutments on the proliferation of human gingival fibroblasts.
MATERIALS AND METHODS
The focus question of this review was: Which material/surface characteristics used for dental implant abutments influence/enhance proliferation of human gingival fibroblasts? The Medline/PubMed, Embase, and Cochrane Library databases were searched using "gingiva," "fibroblasts," "proliferation," and "dental implant abutments" as main keywords with AND/OR as Boolean operators. In vitro studies reporting 3 to 4 or 6 to 7 days of cell proliferation, surface hydrophilicity, and roughness were included. A quality assessment of the selected studies was performed using the web-based Science in Risk Assessment and Policy (SciRAP) tool.
RESULTS
The search identified 1,144 studies, and 44 were eligible for inclusion. The average reporting quality SciRAP score was 82.87 ± 10.68, and the average methodologic quality SciRAP score was 87.35 ± 10.55. Machined, polished, and coated titanium and zirconia surfaces were most commonly investigated. Several studies analyzed aluminum oxide, cobalt-chrome-molybdenum alloy, lithium disilicate, polyether ether ketone, polymer-infiltrated ceramic network, and bioglass. The best cell proliferation was observed on zirconia and on titanium harboring nanotubules or microgrooves. UV treatment, polydopamine, and nitride coatings also improved cell proliferation. Due to the heterogeneity of the data, no correlation could be established between cell profileration and surface hydrophilicity or roughness. However, surface roughness in the range of R = 15 to 145 nm and Sa = 19 to 500 nm on titanium and zirconia proved most suitable.
CONCLUSION
Titanium surfaces with directional guidance patterning and zirconia surfaces best supported cell proliferation during the first week of cell culture. Lack of standardization in surface definitions (machined or polished), methodology, and reporting prevented analytical comparison and should be imposed in future studies.
Topics: Cell Proliferation; Dental Abutments; Dental Implants; Dental Materials; Fibroblasts; Gingiva; Humans; Materials Testing; Surface Properties; Titanium; Zirconium
PubMed: 33616578
DOI: 10.11607/ijp.7388 -
The Cochrane Database of Systematic... Sep 2015Central venous catheter-related bloodstream infection is an important cause of mortality and morbidity in newborn infants cared for in neonatal units. Potential... (Review)
Review
BACKGROUND
Central venous catheter-related bloodstream infection is an important cause of mortality and morbidity in newborn infants cared for in neonatal units. Potential strategies to prevent these infections include the use of central venous catheters impregnated with antimicrobial agents.
OBJECTIVES
To determine the effect of antimicrobial-impregnated central venous catheters in preventing catheter-related bloodstream infection in newborn infants.
SEARCH METHODS
We searched the Cochrane Central Register of Controlled Trials (CENTRAL 2015, Issue 8), MEDLINE (1966 to September 2015), EMBASE (1980 to September 2015), CINAHL (1982 to September 2015), conference proceedings and previous reviews.
SELECTION CRITERIA
Randomised or quasi-randomised controlled trials comparing central venous catheters impregnated or coated with any antibiotic or antiseptic versus central venous catheters without antibiotic or antiseptic coating or impregnation in newborn infants.
DATA COLLECTION AND ANALYSIS
We extracted data using the standard methods of the Cochrane Neonatal Group, with independent evaluation of risk of bias and data extraction by two review authors.
MAIN RESULTS
We found only one small trial (N = 98). This trial found that silver zeolite-impregnated umbilical venous catheters reduced the incidence of bloodstream infection in very preterm infants (risk ratio 0.11, 95% confidence interval 0.01 to 0.87; risk difference -0.17, 95% CI -0.30 to -0.04; number needed to treat for benefit 6, 95% CI 3 to 25].
AUTHORS' CONCLUSIONS
Although the data from one small trial indicates that antimicrobial-impregnated central venous catheters might prevent catheter-related bloodstream infection in newborn infants, the available evidence is insufficient to guide clinical practice. A large, simple and pragmatic randomised controlled trial is needed to resolve on-going uncertainty.
Topics: Anti-Infective Agents; Catheter-Related Infections; Central Venous Catheters; Humans; Infant, Newborn; Silver Compounds; Umbilical Veins; Zeolites
PubMed: 26409791
DOI: 10.1002/14651858.CD011078.pub2 -
Journal of Indian Prosthodontic Society 2022Several methods have been proposed to increase bonding of zirconia with resin. However, we are still to find the Holy Grail. A systematic literature review was performed...
Several methods have been proposed to increase bonding of zirconia with resin. However, we are still to find the Holy Grail. A systematic literature review was performed through PubMed on international literature from January 2000 to May 2021 with relevant Medical Subject Headings terms. 56 articles were found to be relevant. Of all the different methods proposed, mechanochemical pretreatment of zirconia surface with alumina oxide and use of 10-methacryloyloxydecyl dihydrogen phosphate were found to be most effective as per majority of studies. New methods that require further research also surfaced.
Topics: Resin Cements; Dental Bonding; Zirconium; Aluminum Oxide
PubMed: 36510943
DOI: 10.4103/jips.jips_478_21 -
The Journal of Adhesive Dentistry Apr 2022To identify the most effective cleaning method for saliva-contaminated zirconia surface before adhesive cementation through a systematic review and meta-analysis. (Meta-Analysis)
Meta-Analysis
PURPOSE
To identify the most effective cleaning method for saliva-contaminated zirconia surface before adhesive cementation through a systematic review and meta-analysis.
MATERIALS AND METHODS
PubMed, Scopus, and Web of Science databases were searched to select in vitro studies published through October 2021. Studies that did not perform aging methods, had a sample size less than 5 per group, or did not present a group with zirconia contaminated only with saliva were excluded. Data were extracted and risk of bias was assessed. Statistical analysis comparing the cleaning methods was conducted, and the standardized mean difference was assessed using the R software program.
RESULTS
Among 804 potentially eligible studies, 36 were selected for full-text reading, of which 13 were included in qualitative analysis, and 11 of these were subsequently included in the quantitative analysis. A meta-analysis revealed a significant difference in the bond strength between the cleaning methods. Sandblasting with Al2O3 showed a higher bond strength than cleaning solution (Ivoclean, Ivoclar Vivadent) (p < 0.01, I2 = 65%), and both methods promoted higher resin-bond strength to zirconia than water cleaning. In addition, there was no significant difference in the bond strength between alcohol (p = 0.35, I2 = 79%), phosphoric acid (p < 0.23, I2 = 90%), and water cleaning.
CONCLUSION
Sandblasting with Al2O3 seems to be the best method for zirconia surface cleaning before adhesive luting, promoting better resin-bond strength to zirconia.
Topics: Aluminum Oxide; Dental Bonding; Dental Cements; Dental Stress Analysis; Glass Ionomer Cements; Materials Testing; Resin Cements; Saliva; Surface Properties; Water; Zirconium
PubMed: 35416445
DOI: 10.3290/j.jad.b2916437 -
The International Journal of Oral &... Feb 2024To determine the characteristics of dental implant transmucosal surfaces that influence soft tissue attachment and marginal bone loss (MBL).
PURPOSE
To determine the characteristics of dental implant transmucosal surfaces that influence soft tissue attachment and marginal bone loss (MBL).
MATERIALS AND METHODS
The PubMed, Embase, and Cochrane Library electronic databases were searched based on predefined PICO eligibility criteria. Data from animal studies that compared junctional epithelium and connective tissue attachment and MBL from 4 days to 72 weeks were analyzed. The risk of bias was performed with the Systematic Review Centre for Laboratory Animal Experimentation tool. A rank analysis evaluation of data was performed, and the most frequently appearing materials/surfaces for each tissue compartment were identified.
RESULTS
The search identified 3,549 studies, 28 of which were eligible for analysis, with an average risk of bias of 28% ± 10%. Machined, polished, etched, sandblasted, or coated titanium and zirconia materials/surfaces were most frequently examined. Several studies investigated lithium disilicate, polyether ether ketone (PEEK) or polyether ketone ketone (PEKK), aluminum oxide, and gold. Based on ranking and frequency of use at different time points, titanium grade IV (Ti-4) microthreads with a polished neck area most frequently supported natural tooth-like junctional epithelial attachment (≤ 1.5 mm), while machined Ti-4 and machined titanium grade V (Ti-5) most frequently supported connective tissue attachment (≤ 1.25 mm) and led to the least MBL (≤ 0.75 mm).
CONCLUSIONS
Analyzed data suggest that Ti-4 microthreads with a polished neck area and machined Ti-4 and Ti-5 were the materials/surfaces of choice for the transmucosal part of implants. However, the extensive heterogeneity in reported studies precludes solid identification of the best materials/surfaces.
Topics: Animals; Dental Implants; Titanium; Bone Diseases, Metabolic; Aluminum Oxide; Epithelial Attachment
PubMed: 38416011
DOI: 10.11607/jomi.10398 -
Environmental Science and Pollution... Aug 2021Knowledge of the behavior of highly compacted expansive clays, as an engineered barrier, in disposal of high-level nuclear waste (HLW) systems to prevent the pollution... (Review)
Review
Knowledge of the behavior of highly compacted expansive clays, as an engineered barrier, in disposal of high-level nuclear waste (HLW) systems to prevent the pollution due to migration of radionuclide is extremely essential. The prominent properties of globally and widely used bentonites have been extensively studied during past two decades. In China, GaoMiaoZi (GMZ) bentonite is the first choice as a buffer or backfill material for deep geological repositories. This review article presents the recent progresses of knowledge on water retention properties, hydromechanical behavior, and fractal characteristics of GMZ bentonite-based materials, by reviewing 217 internationally published research articles. Firstly, the current literature regarding hydrogeochemical and mechanical characteristics of GMZ bentonite influenced by various saline solutions are critically summarized and reviewed. Then, the role of osmotic suction π alongside the application of surface fractal dimension D is presented from the standpoint of fractal theory. Finally, the strength characteristics of GMZ bentonites using fractal approach have been discussed. Furthermore, this study sheds light on gaps, opportunities, and further research for understanding and analyzing the long-term hydromechanical characteristics of the designed backfill material, from the standpoint of surface fractality of bentonites, and implications of sustainable buffer materials in the field of geoenvironmental engineering.
Topics: Bentonite; Clay; Fractals; Radioactive Waste; Refuse Disposal
PubMed: 34185270
DOI: 10.1007/s11356-021-14707-7 -
Complementary Therapies in Medicine Dec 2018To evaluate the benefits and harms of pediatric Tui Na as a non-pharmaceutical Chinese medicine therapy for acute diarrhea in children under 5 years of age. (Meta-Analysis)
Meta-Analysis
OBJECTIVE
To evaluate the benefits and harms of pediatric Tui Na as a non-pharmaceutical Chinese medicine therapy for acute diarrhea in children under 5 years of age.
DESIGN
Systematic review and meta-analysis of randomized clinical trials.
METHODS
We searched seven major English and Chinese databases from their inception to January 2018 for randomized clinical trials (RCTs) comparing pediatric Tui Na therapy with conventional medicine (montmorillonite/diosmectite or probiotics used alone or in combination). Two authors extracted data and assessed the Cochrane risk of bias, independently. The primary outcomes are clinical cure rate and diarrhea duration from admission to the cessation of diarrhea. 'Clinical cure' is defined as the frequency, timing and character of stool back to normal status, as well as disappearance of diarrhea symptoms. We present dichotomous data as risk ratio (RR), and continuous data as mean difference (MD) with their 95% confidence interval (CI). We used the Cochrane's Revman software (v.5.3) for data analysis. Trial sequential analysis (TSA) was applied to calculate the required sample size in a meta-analysis and detect the robustness of the results. The GRADEpro was used to generate a summary of finding table.
RESULTS
Totally 26 RCTs were included, involving 2410 children with acute diarrhea. Most of the included trials had high or unclear risk of bias in terms of random sequence generation, blinding, and incomplete outcome reporting. The pooled results demonstrated that pediatric Tui Na was superior to montmorillonite after three-session treatment (RR 1.45, 95% CI 1.29-1.62, n = 772, 10 trials), and also superior to montmorillonite combined with probiotics after three-session treatment (RR 2.04, 95% CI 1.49-2.78, n = 533, 7 trials) and after six-session treatment (RR 1.52, 95% CI 1.34-1.73, n = 631, 5 trials) in improving clinical cure rate. Pediatric Tui Na significantly decreased the duration of acute diarrhea (hrs) (MD -0.40 h, 95% CI -15.31 to -5.48 h, n = 410, 6 trials) and daily stool frequency (MD -1.71times, 95% CI -2.37 to -1.04, n = 217, 3 trials, after three-session treatment). No adverse event related to pediatric Tui Na was reported in the included trials. The quality of evidence of included trials was generally moderate to low. TSA for cure rate demonstrated that the pooled data reached a sufficient power regarding both numbers of trials and participants.
CONCLUSIONS
This review shows pediatric Tui Na appears to be effective and safe in improving clinical cure rate and shortening diarrhea duration in childhood aged less than five years of age with acute diarrhea. However, rigorously designed well-reported RCTs are warranted to confirm the findings.
Topics: Acupuncture Points; Acute Disease; Bentonite; Child, Preschool; Defecation; Diarrhea; Female; Humans; Infant; Infant, Newborn; Male; Massage; Medicine, Chinese Traditional; Pediatrics; Probiotics; Randomized Controlled Trials as Topic
PubMed: 30477824
DOI: 10.1016/j.ctim.2018.08.011 -
Molecules (Basel, Switzerland) Oct 2021Zeolites and zeolitic imidazolate frameworks (ZIFs) are widely studied as drug carrying nanoplatforms to enhance the specificity and efficacy of traditional anticancer...
Zeolites and zeolitic imidazolate frameworks (ZIFs) are widely studied as drug carrying nanoplatforms to enhance the specificity and efficacy of traditional anticancer drugs. At present, there is no other systematic review that assesses the potency of zeolites/ZIFs as anticancer drug carriers. Due to the porous nature and inherent pH-sensitive properties of zeolites/ZIFs, the compounds can entrap and selectively release anticancer drugs into the acidic tumor microenvironment. Therefore, it is valuable to provide a comprehensive overview of available evidence on the topic to identify the benefits of the compound as well as potential gaps in knowledge. The purpose of this study was to evaluate the potential therapeutic applications of zeolites/ZIFs as drug delivery systems delivering doxorubicin (DOX), 5-fluorouracil (5-FU), curcumin, cisplatin, and miR-34a. Following PRISMA guidelines, an exhaustive search of PubMed, Scopus, Embase, and Web of Science was conducted. No language or time limitations were used up to 25th August 2021. Only full text articles were selected that pertained to the usage of zeolites/ZIFs in delivering anticancer drugs. Initially, 1279 studies were identified, of which 572 duplicate records were excluded. After screening for the title, abstract, and full texts, 53 articles remained and were included in the qualitative synthesis. An Inter-Rater Reliability (IRR) test, which included a percent user agreement and reliability percent, was conducted for the 53 articles. The included studies suggest that anticancer drug-incorporated zeolites/ZIFs can be used as alternative treatment options to enhance the efficacy of cancer treatment by mitigating the drawbacks of drugs under conventional treatment.
Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Male; Nanoparticles; Neoplasms; Porosity; Tumor Cells, Cultured; Tumor Microenvironment; Zeolites
PubMed: 34684777
DOI: 10.3390/molecules26206196 -
Journal of Environmental Management Feb 2024Meta-analysis of red mud-related literature in English published from 1976 to 2022 and in Chinese from 1990 to 2022 was performed to support critical analysis and... (Meta-Analysis)
Meta-Analysis
Meta-analysis of red mud-related literature in English published from 1976 to 2022 and in Chinese from 1990 to 2022 was performed to support critical analysis and evaluation of the available literature based on the following aspects of red mud research: (a) characterization, (b) treatment for harmfulness minimization, (c) recovery of valuable metals, (d) environmental applications, and (e) uses as construction materials. It was found that (a) sinter red mud tended to contain more silica and calcium, and less iron, sodium and aluminium compared to Bayer red mud; (b) gypsum was the most frequently used agent for harmfulness reduction treatment of red mud, followed by flue gas/CO; (c) the mean optimal pH for adsorption of major anionic pollutants was 8.42 ± 1.13 (arsenite), 3.73 ± 0.68 (arsenate), 3.50 ± 2.38 (phosphate), 4.43 ± 1.04 (fluoride) and 3.80 ± 1.54 (chromate); (d) wastewater treatment has attracted more attention compared to contaminated soils and waste gases; (e) recovery of iron and scandium has attracted more attention compared to other metals; (f) cement making has been the focus in construction uses. Most of the research findings were based on laboratory-scale experiments that focused on efficacy rather than efficiency. There was a lack of integrated approaches for research in red mud valorization.
Topics: Aluminum Oxide; Environmental Pollution; Metals; Iron; Aluminum
PubMed: 38043310
DOI: 10.1016/j.jenvman.2023.119660