-
BMJ (Clinical Research Ed.) Jan 2022To present a comprehensive review of the association between measures of body weight, waist, and fat, and different ratios of these measures, and the risk of type 2... (Meta-Analysis)
Meta-Analysis
OBJECTIVE
To present a comprehensive review of the association between measures of body weight, waist, and fat, and different ratios of these measures, and the risk of type 2 diabetes.
DESIGN
Systematic review and dose-response meta-analysis of cohort studies.
DATA SOURCES
PubMed, Scopus, and Web of Science up to 1 May 2021.
REVIEW METHODS
Cohort studies looking at the association between general or central adiposity and body fat content and the risk of type 2 diabetes in the general adult population were included. Two of the authors extracted the data in duplicate. Random effects dose-response meta-analyses were performed to estimate the degree of the associations. Curvilinear associations were modelled with a one stage weighted mixed effects meta-analysis.
RESULTS
216 cohort studies with 2.3 million individuals with type 2 diabetes among 26 million participants were identified. Relative risks were 1.72 (95% confidence interval 1.65 to 1.81; n=182 studies) for an increase in body mass index of 5 units, 1.61 (1.52 to 1.70; n=78) for a 10 cm larger waist circumference, 1.63 (1.50 to 1.78; n=34) for an increase in waist-to-hip ratio of 0.1 units, 1.73 (1.51 to 1.98; n=25) for an increase in waist-to-height ratio of 0.1 units, 1.42 (1.27 to 1.58; n=9) for an increase in visceral adiposity index of 1 unit, 2.05 (1.41 to 2.98; n=6) for a 10% higher percentage body fat, 1.09 (1.05 to 1.13, n=5) for an increase in body shape index of 0.005 units, 2.55 (1.59 to 4.10, n=4) for a 10% higher body adiposity index, and 1.11 (0.98 to 1.27; n=14) for a 10 cm larger hip circumference. A strong positive linear association was found between body mass index and the risk of type 2 diabetes. Positive linear or monotonic associations were also found in all regions and ethnicities, without marked deviation from linearity at a specific cut-off value. Indices of central fatness, independent of overall adiposity, also had positive linear or monotonic associations with the risk of type 2 diabetes. Positive linear or monotonic associations were also found for total and visceral fat mass, although the number of studies was small.
CONCLUSIONS
A higher body mass index was associated with a greater risk of developing type 2 diabetes. A larger waist circumference, independent of overall adiposity, was strongly and linearly associated with the risk of type 2 diabetes.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42021255338.
Topics: Adipose Tissue; Adiposity; Adult; Aged; Anthropometry; Body Mass Index; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; Male; Middle Aged; Obesity; Waist Circumference; Waist-Height Ratio; Waist-Hip Ratio; Young Adult
PubMed: 35042741
DOI: 10.1136/bmj-2021-067516 -
International Journal of Environmental... Jun 2021Anthropometrics are a set of direct quantitative measurements of the human body's external dimensions, which can be used as indirect measures of body composition. Due to... (Review)
Review
Anthropometrics are a set of direct quantitative measurements of the human body's external dimensions, which can be used as indirect measures of body composition. Due to a number of limitations of conventional manual techniques for the collection of body measurements, advanced systems using three-dimensional (3D) scanners are currently being employed, despite being a relatively new technique. A systematic review was carried out using Pubmed, Medline and the Cochrane Library to assess whether 3D scanners offer reproducible, reliable and accurate data with respect to anthropometrics. Although significant differences were found, 3D measurements correlated strongly with measurements made by conventional anthropometry, dual-energy X-ray absorptiometry (DXA) and air displacement plethysmography (ADP), among others. In most studies (61.1%), 3D scanners were more accurate than these other techniques; in fact, these scanners presented excellent accuracy or reliability. 3D scanners allow automated, quick and easy measurements of different body tissues. Moreover, they seem to provide reproducible, reliable and accurate data that correlate well with the other techniques used.
Topics: Absorptiometry, Photon; Anthropometry; Body Composition; Humans; Plethysmography; Reproducibility of Results; Somatotypes
PubMed: 34201258
DOI: 10.3390/ijerph18126213 -
Journal of Foot and Ankle Research 2018Flexible flat foot is a normal observation in typically developing children, however, some children with flat feet present with pain and impaired lower limb function.... (Review)
Review
BACKGROUND
Flexible flat foot is a normal observation in typically developing children, however, some children with flat feet present with pain and impaired lower limb function. The challenge for health professionals is to identify when foot posture is outside of expected findings and may warrant intervention. Diagnoses of flexible flat foot is often based on radiographic or clinical measures, yet the validity and reliability of these measures for a paediatric population is not clearly understood. The aim of this systematic review was to investigate how paediatric foot posture is defined and measured within the literature, and if the psychometric properties of these measures support any given diagnoses.
METHODS
Electronic databases (MEDLINE, CINAHL, EMBASE, Cochrane, AMED, SportDiscus, PsycINFO, and Web of Science) were systematically searched in January 2017 for empirical studies where participants had diagnosed flexible flat foot and were aged 18 years or younger. Outcomes of interest were the foot posture measures and definitions used. Further articles were sought where cited in relation to the psychometric properties of the measures used.
RESULTS
Of the 1101 unique records identified by the searches, 27 studies met the inclusion criteria involving 20 foot posture measures and 40 definitions of paediatric flexible flat foot. A further 18 citations were sought in relation to the psychometric properties of these measures. Three measures were deemed valid and reliable, the FPI-6 > + 6 for children aged three to 15 years, a Staheli arch index of > 1.07 for children aged three to six and ≥ 1.28 for children six to nine, and a Chippaux-Smirak index of > 62.7% in three to seven year olds, > 59% in six to nine year olds and ≥ 40% for children aged nine to 16 years. No further measures were found to be valid for the paediatric population.
CONCLUSION
No universally accepted criteria for diagnosing paediatric flat foot was found within existing literature, and psychometric data for foot posture measures and definitions used was limited. The outcomes of this review indicate that the FPI - 6, Staheli arch index or Chippaux-Smirak index should be the preferred method of paediatric foot posture measurement in future research.
Topics: Anthropometry; Child; Child Development; Flatfoot; Foot; Humans; Posture; Psychometrics; Reproducibility of Results; Research Design
PubMed: 29854006
DOI: 10.1186/s13047-018-0264-3 -
The British Journal of Nutrition Dec 2020This systematic review and meta-analysis compared the effects of different rates of weight loss (WL), but equivalent total WL, on body composition and RMR. Studies... (Meta-Analysis)
Meta-Analysis
This systematic review and meta-analysis compared the effects of different rates of weight loss (WL), but equivalent total WL, on body composition and RMR. Studies examining gradual v. rapid WL on body composition and RMR in participants with overweight/obesity published up to October 2019 were identified through PubMed, the Cochrane Library, Web of Science, Embase, Scopus and Ovid databases. Meta-analysis was carried out using a fixed or random effects model as appropriate. Although the magnitude of WL was similar (mean difference 0·03 kg, 95 % CI –0·65, 0·71), gradual WL promoted greater reductions in fat mass (FM) (–1 kg, 95 % CI –1·70, –0·29) and body fat percentage (BFP) (–0·83 %, 95 % CI –1·49, –0·17). Gradual WL significantly preserved RMR compared with rapid WL (407·48 kJ, 95 % CI 76·76, 118·01). However, there was no significant difference in waist and hip circumferences, waist:hip ratio and fat-free mass (FFM) between gradual and rapid WL. The present systematic review and meta-analysis indicates beneficial effects of gradual WL, as compared with rapid WL, on FM, BFP and RMR in individuals with overweight/obesity. However, FFM changes and anthropometric indices did not significantly differ following different rates of WL.
Topics: Adolescent; Adult; Aged; Anthropometry; Basal Metabolism; Body Composition; Body Mass Index; Female; Humans; Male; Middle Aged; Obesity; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; Weight Loss; Young Adult
PubMed: 32576318
DOI: 10.1017/S000711452000224X -
Obesity Reviews : An Official Journal... Aug 2022Excess visceral adiposity contributes to elevated cardiometabolic risk, and waist circumference is commonly used as a surrogate measure of visceral adipose tissue.... (Meta-Analysis)
Meta-Analysis Review
Excess visceral adiposity contributes to elevated cardiometabolic risk, and waist circumference is commonly used as a surrogate measure of visceral adipose tissue. Although regular aerobic exercise is known to improve abdominal obesity, its effect on waist circumference is unclear. A systematic review and meta-analysis was performed to determine (1) the effect of aerobic exercise on waist circumference in adults with overweight or obesity; (2) the association between any change in waist circumference and change in visceral adipose tissue and/or bodyweight with aerobic exercise interventions; and (3) if reductions in waist circumference with exercise are moderated by clinical characteristics or components of aerobic exercise prescription. Twenty-five randomized controlled trials (1686 participants) were included. Regular aerobic exercise significantly reduced waist circumference by 3.2 cm (95% confidence interval [CI] -3.86, -2.51, p ≤ 0.001) versus control. Change in waist circumference was associated with change in visceral adipose tissue (β = 4.02; 95% CI 1.37, 6.66, p = 0.004), and vigorous intensity produced superior reduction (-4.2 cm, 95% CI -4.99, -3.42, p < 0.0001) in waist circumference compared with moderate intensity (-2.50 cm, 95% CI -3.22, -1.79, p = 0.058). These findings suggest regular aerobic exercise results in modest reductions in waist circumference and associated visceral adipose tissue and that higher intensity exercise may offer superior benefit to moderate intensity.
Topics: Adult; Body Mass Index; Exercise; Humans; Obesity; Obesity, Abdominal; Overweight; Waist Circumference; Weight Loss
PubMed: 35383401
DOI: 10.1111/obr.13446 -
BMJ (Clinical Research Ed.) Sep 2020To quantify the association of indices of central obesity, including waist circumference, hip circumference, thigh circumference, waist-to-hip ratio, waist-to-height... (Meta-Analysis)
Meta-Analysis
OBJECTIVE
To quantify the association of indices of central obesity, including waist circumference, hip circumference, thigh circumference, waist-to-hip ratio, waist-to-height ratio, waist-to-thigh ratio, body adiposity index, and A body shape index, with the risk of all cause mortality in the general population, and to clarify the shape of the dose-response relations.
DESIGN
Systematic review and meta-analysis.
DATA SOURCES
PubMed and Scopus from inception to July 2019, and the reference lists of all related articles and reviews.
ELIGIBILITY CRITERIA FOR SELECTING STUDIES
Prospective cohort studies reporting the risk estimates of all cause mortality across at least three categories of indices of central fatness. Studies that reported continuous estimation of the associations were also included.
DATA SYNTHESIS
A random effects dose-response meta-analysis was conducted to assess linear trend estimations. A one stage linear mixed effects meta-analysis was used for estimating dose-response curves.
RESULTS
Of 98 745 studies screened, 1950 full texts were fully reviewed for eligibility. The final analyses consisted of 72 prospective cohort studies with 2 528 297 participants. The summary hazard ratios were as follows: waist circumference (10 cm, 3.94 inch increase): 1.11 (95% confidence interval 1.08 to 1.13, I=88%, n=50); hip circumference (10 cm, 3.94 inch increase): 0.90 (0.81 to 0.99, I=95%, n=9); thigh circumference (5 cm, 1.97 inch increase): 0.82 (0.75 to 0.89, I=54%, n=3); waist-to-hip ratio (0.1 unit increase): 1.20 (1.15 to 1.25, I=90%, n=31); waist-to-height ratio (0.1 unit increase): 1.24 (1.12 to 1.36, I=94%, n=11); waist-to-thigh ratio (0.1 unit increase): 1.21 (1.03 to 1.39, I=97%, n=2); body adiposity index (10% increase): 1.17 (1.00 to 1.33, I=75%, n=4); and A body shape index (0.005 unit increase): 1.15 (1.10 to 1.20, I=87%, n=9). Positive associations persisted after accounting for body mass index. A nearly J shaped association was found between waist circumference and waist-to-height ratio and the risk of all cause mortality in men and women. A positive monotonic association was observed for waist-to-hip ratio and A body shape index. The association was U shaped for body adiposity index.
CONCLUSIONS
Indices of central fatness including waist circumference, waist-to-hip ratio, waist-to-height ratio, waist-to-thigh ratio, body adiposity index, and A body shape index, independent of overall adiposity, were positively and significantly associated with a higher all cause mortality risk. Larger hip circumference and thigh circumference were associated with a lower risk. The results suggest that measures of central adiposity could be used with body mass index as a supplementary approach to determine the risk of premature death.
Topics: Body Mass Index; Humans; Obesity, Abdominal; Waist Circumference; Waist-Hip Ratio
PubMed: 32967840
DOI: 10.1136/bmj.m3324 -
International Journal of Obesity (2005) Oct 2020Numerous studies have reported the association of ultra-processed foods with excess body weight; however, the nature and extent of this relation has not been clearly... (Meta-Analysis)
Meta-Analysis
BACKGROUND
Numerous studies have reported the association of ultra-processed foods with excess body weight; however, the nature and extent of this relation has not been clearly established. This systematic review was conducted to analyze the currently documented evidence regarding the association between ultra-processed food with overweight and obesity.
METHODS
A literature search was performed using multiple literature databases for relevant articles published prior to November 2019. Random effects model, namely the DerSimonian-Laird method, was applied to pool effect sizes. The potential sources of heterogeneity across studies were explored using the Cochrane Q test.
RESULTS
Fourteen studies (one cohort study and thirteen cross-sectional studies) were included in this review. A significant association was identified between ultra-processed food intake and overweight (pooled effect size: 1.02; 95% confidence interval (95% CI): 1.01, 1.03, p < 0.001) and obesity (pooled effect size: 1.26; 95% CI: 1.13, 1.41, p < 0.001).
CONCLUSION
Our findings revealed a positive association between ultra-processed foods and excess body weight. Future studies with longitudinal designs and adequate control for confounding factors are required to clarify whether ultra-processed food intake alters anthropometric parameters and leads to obesity.
Topics: Anthropometry; Fast Foods; Humans; Obesity; Observational Studies as Topic; Overweight
PubMed: 32796919
DOI: 10.1038/s41366-020-00650-z -
Obesity Reviews : An Official Journal... Jul 2020There is an ongoing debate about the possible influences of nonnutritive sweeteners (NNS) on body weight. We conducted a systematic review and meta-analysis of... (Meta-Analysis)
Meta-Analysis
There is an ongoing debate about the possible influences of nonnutritive sweeteners (NNS) on body weight. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) with NNS to assess their impact on body weight. We systematically searched for RCTs at least 4 weeks in duration, evaluating the effect of NNS on body weight, both in subjects with healthy weight and in subjects with overweight/obesity at any age, and compared the effects of NNS vs caloric and noncaloric comparators. The primary outcome was the difference in body weight between NNS and comparators. Twenty studies were eligible (n = 2914). Participants consuming NNS showed significant weight/BMI differences favouring NNS compared with nonusers. Grouping by nature of comparator revealed that NNS vs placebo/no intervention and NNS vs water produced no effect. When comparing NNS vs sucrose, significant weight/BMI differences appeared favouring NNS. Consumption of NNS led to significantly negative weight/BMI differences in unrestricted energy diets, but not in weight-reduction diets. Participants with overweight/obesity and adults showed significant favourable weight/BMI differences with NNS. Data suggest that replacing sugar with NNS leads to weight reduction, particularly in participants with overweight/obesity under an unrestricted diet, information that could be utilized for evidence-based public policy decisions.
Topics: Body Mass Index; Body Weight; Diet; Humans; Non-Nutritive Sweeteners; Obesity
PubMed: 32216045
DOI: 10.1111/obr.13020 -
Archivos de Bronconeumologia Jun 2018Lung function reference values are traditionally based on anthropometric factors, such as weight, height, sex, and age. FVC and FEV decline with age, while volumes and...
Lung function reference values are traditionally based on anthropometric factors, such as weight, height, sex, and age. FVC and FEV decline with age, while volumes and capacities, such as RV and FRC, increase. TLC, VC, RV, FVC and FEV are affected by height, since they are proportional to body size. This means that a tall individual will experience greater decrease in lung volumes as they get older. Some variables, such as FRC and ERV, decline exponentially with an increase in weight, to the extent that tidal volume in morbidly obese patients can be close to that of RV. Men have longer airways than women, causing greater specific resistance in the respiratory tract. The increased work of breathing to increase ventilation among women means that their consumption of oxygen is higher than men under similar conditions of physical intensity. Lung volumes are higher when the subject is standing than in other positions. DLCO is significantly higher in supine positions than in sitting or standing positions, but the difference between sitting and standing positions is not significant. Anthropometric characteristics are insufficient to explain differences in lung function between different ethnic groups, underlining the importance of considering other factors in addition to the conventional anthropometric measurements.
Topics: Age Factors; Anthropometry; Ethnicity; Female; Humans; Lung; Male; Posture; Racial Groups; Respiratory Function Tests; Sex Characteristics; Work of Breathing
PubMed: 29496283
DOI: 10.1016/j.arbres.2018.01.030 -
JAMA Pediatrics Mar 2024Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed... (Meta-Analysis)
Meta-Analysis
IMPORTANCE
Concerns have been raised that frequent consumption of 100% fruit juice may promote weight gain. Current evidence on fruit juice and weight gain has yielded mixed findings from both observational studies and clinical trials.
OBJECTIVE
To synthesize the available evidence on 100% fruit juice consumption and body weight in children and adults.
DATA SOURCES
MEDLINE, Embase, and Cochrane databases were searched through May 18, 2023.
STUDY SELECTION
Prospective cohort studies of at least 6 months and randomized clinical trials (RCTs) of at least 2 weeks assessing the association of 100% fruit juice with body weight change in children and adults were included. In the trials, fruit juices were compared with noncaloric controls.
DATA EXTRACTION AND SYNTHESIS
Data were pooled using random-effects models and presented as β coefficients with 95% CIs for cohort studies and mean differences (MDs) with 95% CIs for RCTs.
MAIN OUTCOMES AND MEASURES
Change in body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) was assessed in children and change in body weight in adults.
RESULTS
A total of 42 eligible studies were included in this analysis, including 17 among children (17 cohorts; 0 RCTs; 45 851 children; median [IQR] age, 8 [1-15] years) and 25 among adults (6 cohorts; 19 RCTs; 268 095 adults; median [IQR] age among cohort studies, 48 [41-61] years; median [IQR] age among RCTs, 42 [25-59]). Among cohort studies in children, each additional serving per day of 100% fruit juice was associated with a 0.03 (95% CI, 0.01-0.05) higher BMI change. Among cohort studies in adults, studies that did not adjust for energy showed greater body weight gain (0.21 kg; 95% CI, 0.15-0.27 kg) than studies that did adjust for energy intake (-0.08 kg; 95% CI, -0.11 to -0.05 kg; P for meta-regression <.001). RCTs in adults found no significant association of assignment to 100% fruit juice with body weight but the CI was wide (MD, -0.53 kg; 95% CI, -1.55 to 0.48 kg).
CONCLUSION AND RELEVANCE
Based on the available evidence from prospective cohort studies, in this systematic review and meta-analysis, 1 serving per day of 100% fruit juice was associated with BMI gain among children. Findings in adults found a significant association among studies unadjusted for total energy, suggesting potential mediation by calories. Further trials of 100% fruit juice and body weight are desirable. Our findings support guidance to limit consumption of fruit juice to prevent intake of excess calories and weight gain.
Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Infant; Middle Aged; Body Mass Index; Body Weight; Fruit and Vegetable Juices; Randomized Controlled Trials as Topic; Weight Gain
PubMed: 38227336
DOI: 10.1001/jamapediatrics.2023.6124