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Pediatric Blood & Cancer Aug 2017Pediatric central nervous system (CNS) tumor survivors are at high risk for numerous late effects including decreased health-related quality of life (HRQOL). Our... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Pediatric central nervous system (CNS) tumor survivors are at high risk for numerous late effects including decreased health-related quality of life (HRQOL). Our objective was to summarize studies describing HRQOL in pediatric CNS tumor survivors and compare HRQOL outcomes in studies that included a comparison group.
PROCEDURE
EMBASE, MEDLINE, and PsychINFO were used to identify relevant articles published until August, 2016. Eligible studies reported outcomes for pediatric CNS tumor survivors diagnosed before age 21, at least 5 years from diagnosis and/or 2 years off therapy and used a standardized measure of HRQOL. All data were abstracted by two reviewers. Random-effects meta-analyses were performed using Review Manager 5.0.
RESULTS
Of 1,912 unique articles identified, 74 were included in this review. Papers described 29 different HRQOL tools. Meta-analyses compared pediatric CNS tumor survivors to healthy comparisons and other pediatric cancer survivors separately. HRQOL was significantly lower for CNS (n = 797) than healthy comparisons (n = 1,397) (mean difference = -0.54, 95% confidence interval [CI] = -0.72 to -0.35, P < 0.001, I = 35%). HRQOL was also significantly lower for CNS (n = 244) than non-CNS survivors (n = 414) (mean difference = -0.56, 95% CI = -0.73 to -0.38, P < 0.00001, I = 0%).
CONCLUSIONS
Pediatric CNS tumor survivors experience worse HRQOL than healthy comparisons and non-CNS cancer survivors. Future HRQOL work should be longitudinal, and/or multisite studies that examine HRQOL by diagnosis and treatment modalities.
Topics: Central Nervous System Neoplasms; Child; Female; Health Status; Humans; Male; Quality of Life; Survivors
PubMed: 28266804
DOI: 10.1002/pbc.26442 -
Journal of Pediatric Intensive Care Mar 2020The aim of this study was to determine the association between the time of admission (day, night, and/or weekends) and mortality among critically ill children admitted... (Review)
Review
The aim of this study was to determine the association between the time of admission (day, night, and/or weekends) and mortality among critically ill children admitted to a pediatric intensive care unit (PICU). Electronic databases that were searched include PubMed, Embase, Web of Science, CINAHL (Cumulative Index of Nursing and Allied Health Literature), Ovid, and Cochrane Library since inception till June 15, 2018. The article included observational studies reporting inhospital mortality and the time of admission to PICU limited to patients aged younger than 18 years. Meta-analysis was performed by a frequentist approach with both fixed and random effect models. The GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach was used to evaluate the quality of evidence. Ten studies met our inclusion criteria. Five studies comparing weekday with weekend admissions showed better odds of survival on weekdays (odds ratio [OR]: 0.77; 95% confidence interval [CI]: 0.60-0.99). Pooled data of four studies showed that odds of mortality were similar between day and night admissions (OR: 0.93; 95% CI: 0.77-1.13). Similarly, three studies comparing admission during off-hours versus regular hours did not show better odds of survival during regular hours (OR: 0.77; 95% CI: 0.57-1.05). Heterogeneity was significant due to variable sample sizes and time period. Inconsistency in adjusting for confounders across the included studies precluded us from analyzing the adjusted risk of mortality. Weekday admissions to PICU were associated with lesser odds of mortality. No significant differences in the odds of mortality were found between admissions during day versus night or between admission during regular hours and that during off-hours. However, the evidence is of low quality and requires larger prospective studies.
PubMed: 31984150
DOI: 10.1055/s-0039-3399581 -
Pediatrics Oct 2021Daily outdoor play is encouraged by the American Academy of Pediatrics. Existing evidence is unclear on the independent effect of nature exposures on child health.
CONTEXT
Daily outdoor play is encouraged by the American Academy of Pediatrics. Existing evidence is unclear on the independent effect of nature exposures on child health.
OBJECTIVE
We systematically evaluated evidence regarding the relationship between nature contact and children's health.
DATA SOURCES
The database search was conducted by using PubMed, Cumulative Index to Nursing and Allied Health Literature, PsychInfo, ERIC, Scopus, and Web of Science in February 2021.
STUDY SELECTION
We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. In all searches, the first element included nature terms; the second included child health outcome terms.
DATA EXTRACTION
Of the 10 940 studies identified, 296 were included. Study quality and risk of bias were assessed.
RESULTS
The strongest evidence for type of nature exposure was residential green space studies ( = 147, 50%). The strongest evidence for the beneficial health effects of nature was for physical activity ( = 108, 32%) and cognitive, behavioral, or mental health ( = 85, 25%). Physical activity was objectively measured in 55% of studies, and 41% of the cognitive, behavioral, or mental health studies were experimental in design.
LIMITATIONS
Types of nature exposures and health outcomes and behaviors were heterogenous. Risk of selection bias was moderate to high for all studies. Most studies were cross-sectional ( = 204, 69%), limiting our ability to assess causality.
CONCLUSIONS
Current literature supports a positive relationship between nature contact and children's health, especially for physical activity and mental health, both public health priorities. The evidence supports pediatricians in advocating for equitable nature contact for children in places where they live, play, and learn.
Topics: Child; Child Behavior; Child Development; Child Health; Environment; Exercise; Humans; Overweight; Pediatric Obesity; Play and Playthings
PubMed: 34588297
DOI: 10.1542/peds.2020-049155 -
Child Health Nursing Research Jan 2023This systematic literature review and meta-analysis explored extended reality (XR)-based pediatric nursing simulation programs and analyzed their effectiveness.
PURPOSE
This systematic literature review and meta-analysis explored extended reality (XR)-based pediatric nursing simulation programs and analyzed their effectiveness.
METHODS
A literature search was conducted between May 1 and 30, 2022 in the following electronic databases: MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. The search period was from 2000 to 2022. In total, 6,095 articles were reviewed according to the inclusion and exclusion criteria, and 14 articles were selected for the final content analysis and 10 for the meta-analysis. Data analysis was performed using descriptive statistics and the Comprehensive Meta- Analysis program.
RESULTS
XR-based pediatric nursing simulation programs have increased since 2019. Studies using virtual reality with manikins or high-fidelity simulators were the most common, with six studies. The total effect size was statistically significant at 0.84 (95% confidence interval=0.50-1.19, z=4.82, p<.001).
CONCLUSION
Based on the findings, we suggest developing standardized guidelines for the operation of virtual pediatric nursing simulation education and practice. Simultaneously, the application of more sophisticated research designs for effect measurement and the combined applications of various virtual simulation methods are needed to validate the most effective simulation methodology.
PubMed: 36760110
DOI: 10.4094/chnr.2023.29.1.24 -
The Journal of Vascular Access Oct 2022The peripheral intravenous catheter (PIVC) is an important strategy for the treating the illness of pediatric patients. However, the success rate of traditional PIVC... (Review)
Review
BACKGROUND
The peripheral intravenous catheter (PIVC) is an important strategy for the treating the illness of pediatric patients. However, the success rate of traditional PIVC method, such as the landmark technique, might be significantly variable and unstable. The near infrared-assisted PIVC might be another option and the results can be revealed by a systemic review and meta-analysis of randomized clinical trials (RCT).
METHODS
A systematic search and a meta-analysis for the RCT of near infrared-assisted PIVC on pediatric patients. The near infrared-assisted and traditional PIVC was compared to evaluate the first time success rate, number of attempts, and attempt duration. Seven RCT studies and total 1068 pediatric patients were enrolled in this meta-analysis. The subgroup analysis of vessel grade difficulty was also performed.
RESULTS
The near infrared-assisted PIVC showed a significantly higher odds ratio of first time success rate when compared to traditional PIVC. In addition, the number of attempts and attempt duration were significantly reduced in the group of near infrared-assisted PIVC. At last, the subgroup analysis of vessel grade difficultly showed that the first time success rate was borderline significantly increased in the subgroup of difficult vessel grade. In addition, the number of attempts was significantly reduced in the subgroup of difficult vessel grade.
CONCLUSIONS
The near infrared-assisted PIVC might be an option for the PIVC on pediatric patients. The advantages of increased first time success rate and decreased number of attempts and attempt duration should be considered by the clinicians and nurses.
PubMed: 36203373
DOI: 10.1177/11297298221126811 -
Journal of Advanced Nursing Jul 2017The aim of this study was to identify interventions associated with peripheral intravenous catheterization first attempt success in pediatric inpatients and emergency... (Review)
Review
AIM
The aim of this study was to identify interventions associated with peripheral intravenous catheterization first attempt success in pediatric inpatients and emergency department patients who require vascular access for therapeutic interventions.
BACKGROUND
Unsuccessful peripheral intravenous catheterization puts children at risk for increased pain and treatment delays. Effective interventions to increase peripheral intravenous catheterization first attempt success are unclear.
DESIGN
Systematic review of randomized controlled trials according to the Cochrane Handbook for the Systematic Review of Interventions.
DATA SOURCES
Through November and December 2014, we searched 10 databases including MEDLINE (OVID), EMBASE (OVID) and CINAHL (EBSCO) without date limits. The references of articles were also reviewed. We included full text reports of randomized controlled trials testing intervention first attempt success rates vs. standard of care.
REVIEW METHODS
According to inclusion and exclusion criteria set a priori, data were extracted using a standardized tool. We assessed for risk of bias with the Cochrane Collaboration Risk of Bias Tool. Due to unclear reporting narrative synthesis was used to report results.
RESULTS
Four cluster randomized control trials and ten randomized control trials involving 4539 participants ranging from 15·6 days to 16 years of age met our inclusion criteria. We excluded the four cluster trials from meta-analysis due to unclear reporting. Interventions did not increase first attempt success rate compared with standard of care.
CONCLUSIONS
There was insufficient evidence to support the use of ultrasound, infrared light or transillumination. Interventions to reduce children's pain did not decrease first attempt success. Research examining between-clinician proficiency and persistence differences is absent.
Topics: Catheterization, Peripheral; Child; Emergency Service, Hospital; Humans
PubMed: 27864995
DOI: 10.1111/jan.13211 -
Epilepsy & Behavior : E&B Sep 2022Lacosamide (LCM), is a third-generation antiseizure medicine, with limited clinical evidence for use in pediatric populations. We aimed to evaluate evidence for the... (Meta-Analysis)
Meta-Analysis Review
OBJECTIVE
Lacosamide (LCM), is a third-generation antiseizure medicine, with limited clinical evidence for use in pediatric populations. We aimed to evaluate evidence for the efficacy and safety of LCM in pediatric patients with epilepsy.
METHODS
A systematic review was performed using literature published from inception to February 2022 identified in MEDLINE, Embase, Cochrane Library, and four Chinese databases. Efficacy and safety outcome data were collected, and a meta-analysis was performed.
RESULT
Twenty-one studies involving 1230 pediatric patients were included. The median percent reduction in seizure frequency per 28 days from baseline to maintenance was 33.1% (95% confidence interval [CI] 22.7%, 43.5%). After 6 months of treatment, the 50%, 75%, and 100% responder rates were 53.3% (95% CI 40.7%, 65.9%), 28.3% (95% CI 20.8%, 35.8%), and 20.4% (95% CI 12.6%, 28.2%), respectively. After 12 months of treatment, the 50%, 75%, and 100% responder rates were 42.0% (95% CI 29.5%, 54.5%), 19.5% (95% CI 11.1%, 27.8%), and 15.2% (95% CI 6.6%, 23.8%), respectively. The most common adverse events (AEs) were drowsiness (15.0%), dizziness (9.9%), and somnolence (8.3%).
CONCLUSION
Lacosamide is generally effective and well tolerated to use in children with epilepsy. However, further research with high-quality data and long-term follow-up of LCM use in pediatric populations is needed.
Topics: Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Humans; Lacosamide; Sleepiness; Treatment Outcome
PubMed: 35914435
DOI: 10.1016/j.yebeh.2022.108781 -
Journal of Hospital Medicine Oct 2022Pediatric extravasation injuries are significant healthcare-associated injuries, with sometimes significant sequelae. Evidence-based guidance on management is necessary... (Review)
Review
BACKGROUND
Pediatric extravasation injuries are significant healthcare-associated injuries, with sometimes significant sequelae. Evidence-based guidance on management is necessary to prevent permanent injury.
PURPOSE
A systematic review of the literature, including aggregated case series, investigating extravasation injury management of hospitalized pediatric patients.
DATA SOURCES
PubMed, Cummulative Index to Nursing and Allied Health Literature (CINAHL), and Excerpta Medica database (EMBASE) were searched on December 13, 2021.
STUDY SELECTION
Primary research investigating extravasation injury management of hospitalized pediatric patients (to 18 years), published from 2010 onwards and in English, independently screened by two authors, with arbitration from a third author.
DATA EXTRACTION
Data regarding the study, patient (age, primary diagnosis), extravasation (site, presentation, outcome), and treatment (first aid, wound management) were extracted by two authors, with arbitration from a third author.
DATA SYNTHESIS
From an initial 1769 articles, 27 studies were included with extractable case data reported in 18 studies, resulting in 33 cases. No clinical trials were identified, instead, studies were primarily case studies (52%) of neonates (67%), with varied extravasation symptoms. Studies had good selection and ascertainment, but few met the causality and reporting requirements for quality assessments. Signs and symptoms varied, with scarring (45%) and necrosis (30%) commonly described. Diverse treatments were categorized into first aid, medical, surgical, and dressings.
CONCLUSIONS
Despite infiltration and extravasation injuries being common within pediatric healthcare, management interventions are under-researched, with low-quality studies and no consensus on treatments or outcomes.
Topics: Child; Extravasation of Diagnostic and Therapeutic Materials; Humans; Infant, Newborn
PubMed: 36039964
DOI: 10.1002/jhm.12951 -
Annals of Medicine and Surgery (2012) Nov 2023Patient satisfaction (PS) with nursing care is considered one of the most important predictors of satisfaction with hospital services. The current research was conducted...
INTRODUCTION
Patient satisfaction (PS) with nursing care is considered one of the most important predictors of satisfaction with hospital services. The current research was conducted to determine the level of PS with nursing care provided in hospitals in Iran.
METHODS
A comprehensive systematic search was conducted in various international electronic databases, such as PubMed, Scopus, Web of Science, and Persian electronic databases such as Iranmedex, and the Scientific Information Database (SID) using keywords extracted from Medical Subject Headings such as 'Patient satisfaction', 'Satisfaction', 'Nursing care', and 'Nurse' from the earliest to 27 January 2023. The risk of bias was assessed using the Joanna Briggs Institute (JBI) scale, and the analysis was performed in Stata software version 14. Subgroup and sensitivity analyses were performed to clarify the source of heterogeneity.
RESULTS
The results showed that the overall PS with nursing care in different hospitals was 0.83 (95% CI: 0.79-0.86). The proportions of complete satisfaction, partial satisfaction, and dissatisfaction were 0.38 (95% CI: 0.23-0.53), 0.45 (95% CI: 0.34-0.55), and 0.17 (95% CI: 0.12-0.21), respectively.
CONCLUSION
However, overall satisfaction was seen in four out of five patients admitted to hospitals in Iran, complete satisfaction with nursing care was 38%. Future studies should identify the effective factors related to PS with nursing care.
PubMed: 37915670
DOI: 10.1097/MS9.0000000000001309 -
Journal of Holistic Nursing : Official... Mar 2023Since the 1990's aromatherapy has been a popular adjunct to nursing and midwifery care in a variety of health care settings. The scoping review seeks to identify and... (Review)
Review
Since the 1990's aromatherapy has been a popular adjunct to nursing and midwifery care in a variety of health care settings. The scoping review seeks to identify and confirm the benefits of incorporating aromatherapy into holistic nursing and midwifery practice Design: A scoping review using PRISMA-ScR of experimental studies where care is provided to the patient by a registered nurse or midwife. Any health care setting where nurses or midwives provide care. A multi- engine search using a range of MeSH and non-MeSH terms with the Boolean search [AND]. Inclusion criteria were; publication date from 2005-2021, study involved aromatherapy as an intervention, conducted in a clinical nursing or midwifery environment and the published article is available in full in English. Excluded were; single patient cases, animal studies, in vitro studies, use of essential oils internally or a whole plant extract was used or use was non-nursing/midwifery related. 124 studies met the inclusion criteria (n = 19188), classified into seven themes. The evidence supports the use of aromatherapy within a range of nursing and midwifery practices enhancing a holistic model of care. This scoping review contributes evidence to support the inclusion of aromatherapy into holistic nursing and midwifery practice.
Topics: Pregnancy; Humans; Female; Midwifery; Aromatherapy; Nurse Midwives; Oils, Volatile; Delivery of Health Care
PubMed: 35213239
DOI: 10.1177/08980101221078736