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International Journal of Infectious... Feb 2019Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV). The... (Meta-Analysis)
Meta-Analysis
OBJECTIVES
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV). The seroprevalence of anti-SFTSV antibodies specific to SFTSV (IgG or IgM) has been investigated in different animal hosts in many epidemiological studies, but no systematic estimation of seroprevalence has yet been performed. Hence, this meta-analysis was conducted in order to obtain a more comprehensive result to clarify the prevalence of SFTSV in animals.
METHODS
A search for all relevant articles was conducted in the major national and international electronic databases up to August 2018. Data on seroprevalence of SFTSV antibodies (IgM and IgG) were extracted as the primary outcome. The pooled seroprevalence rates and 95% confidence intervals (95% CI) were determined.
RESULTS
Overall, anti-SFTSV antibodies (IgG or IgM) were detected in 15 animal species. The pooled seroprevalence of anti-SFTSV antibodies was 45.70% in goats and sheep, 36.70% in cattle, 29.50% in dogs, 9.60% in chickens, 3.20% in rodents, and 3.20% in pigs. The seroprevalence of SFTSV in animals that had a confined range was significantly lower than that in free-range animals. SFTSV RNA was detected in 11 animal species, with a carriage rate varying from 0.23% to 26.31%.
CONCLUSIONS
SFTSV has a wide spectrum of animal hosts, including domestic and wild animals. The prevalence of SFTSV is high among specific animal species.
Topics: Animals; Antibodies, Viral; Bunyaviridae Infections; Cattle; Chickens; Goats; Immunoglobulin G; Immunoglobulin M; Phlebovirus; Rodentia; Seroepidemiologic Studies; Sheep; Swine; Thrombocytopenia
PubMed: 30500443
DOI: 10.1016/j.ijid.2018.11.017 -
Parasites & Vectors May 2019Arboviruses represent a significant burden to public health and local economies due to their ability to cause unpredictable and widespread epidemics. To maximize early...
Arboviruses represent a significant burden to public health and local economies due to their ability to cause unpredictable and widespread epidemics. To maximize early detection of arbovirus emergence in non-endemic areas, surveillance efforts should target areas where circulation is most likely. However, identifying such hotspots of potential emergence is a major challenge. The ecological conditions leading to arbovirus outbreaks are shaped by complex interactions between the virus, its vertebrate hosts, arthropod vector, and abiotic environment that are often poorly understood. Here, we systematically review the ecological risk factors associated with the circulation of six arboviruses that are of considerable concern to northwestern Europe. These include three mosquito-borne viruses (Japanese encephalitis virus, West Nile virus, Rift Valley fever virus) and three tick-borne viruses (Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis virus, and louping-ill virus). We consider both intrinsic (e.g. vector and reservoir host competence) and extrinsic (e.g. temperature, precipitation, host densities, land use) risk factors, identify current knowledge gaps, and discuss future directions. Our systematic review provides baseline information for the identification of regions and habitats that have suitable ecological conditions for endemic circulation, and therefore may be used to target early warning surveillance programs aimed at detecting multi-virus and/or arbovirus emergence.
Topics: Animals; Arbovirus Infections; Arboviruses; Arthropod Vectors; Disease Vectors; Encephalitis Virus, Japanese; Europe; Humans; Mosquito Vectors; Rift Valley fever virus; Risk Factors; West Nile virus
PubMed: 31133059
DOI: 10.1186/s13071-019-3515-7