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Primary Care Dec 2015Acne is a common complaint in the primary care clinics. It has not only physical implications but also psychological. This article discusses the epidemiology,... (Review)
Review
Acne is a common complaint in the primary care clinics. It has not only physical implications but also psychological. This article discusses the epidemiology, pathophysiology, and criteria for making the diagnosis. It also discusses endocrine disorders that may be the cause of acne. Treatment and management are discussed by subtype. Acne mechanica or sports-related acne is also discussed.
Topics: Acne Vulgaris; Administration, Cutaneous; Anti-Bacterial Agents; Contraceptives, Oral, Hormonal; Diagnosis, Differential; Humans; Primary Health Care; Retinoids; Severity of Illness Index
PubMed: 26612368
DOI: 10.1016/j.pop.2015.07.007 -
Journal Der Deutschen Dermatologischen... Jul 2017Akne ist eine chronische Erkrankung mit hoher Prävalenz unter Jugendlichen. Pathogenetische Hauptfaktoren (und ihre klinischen Korrelate) sind gesteigerte... (Review)
Review
Akne ist eine chronische Erkrankung mit hoher Prävalenz unter Jugendlichen. Pathogenetische Hauptfaktoren (und ihre klinischen Korrelate) sind gesteigerte Talgproduktion (Seborrhoe), follikuläre Hyperkeratose (Komedonen) und perifollikuläre Entzündungsvorgänge (Papulopusteln). Die Krankheit wird von endogenen (Androgene, IGF-1, neuroendokrine Faktoren) und exogenen (Propionibacterium acnes, Diät, mechanische Irritation, Inhaltsstoffe medizinischer oder kosmetischer Externa) Einflüssen moduliert. Akne geht mit zum Teil hoher Morbidität einher und kann bereits bei leichter Ausprägung eine erhebliche Verschlechterung der Lebensqualität bewirken. Zu Therapie stehen wirksame topische und systemische Behandlungsverfahren zur Verfügung. Eine optimale Behandlung erfordert eine stadiengerechtes Management und kontinuierliche ärztliche Begleitung der Patienten über den erforderlichen Behandlungszeitraum.
Topics: Acne Vulgaris; Adolescent; Age Factors; Androgens; Anti-Bacterial Agents; Child; Combined Modality Therapy; Cross-Sectional Studies; Dermatologic Agents; Female; Guideline Adherence; Humans; Isotretinoin; Male; Quality of Life; Risk Factors; Skin
PubMed: 28677193
DOI: 10.1111/ddg.30_13278 -
Dermatologic Clinics Apr 2016Acne vulgaris presenting from birth to preadolescence can be confusing to diagnose and even more challenging to evaluate and manage. The differential diagnosis of acne... (Review)
Review
Acne vulgaris presenting from birth to preadolescence can be confusing to diagnose and even more challenging to evaluate and manage. The differential diagnosis of acne varies by age and, in some cases (especially when it presents in midchildhood), deserves a thorough evaluation to rule out underlying systemic abnormalities. Acne management strategies, including factors affecting adherence to the treatment regimen, may be influenced by the patient's age. This article presents an overview of the clinical presentations of acne by age and our approach to evaluation and management of this common condition.
Topics: Acne Vulgaris; Child; Child, Preschool; Dermatologic Agents; Disease Management; Humans; Infant; Infant, Newborn
PubMed: 27015779
DOI: 10.1016/j.det.2015.11.006 -
Journal of Drugs in Dermatology : JDD Jun 2023Acne vulgaris is the most common skin condition in the US, affecting up to 50 million Americans. The American Academy of Dermatology (AAD) guidelines on acne treatment...
Acne vulgaris is the most common skin condition in the US, affecting up to 50 million Americans. The American Academy of Dermatology (AAD) guidelines on acne treatment were developed to provide recommendations for the diagnosis, grading, and treatment of acne in adolescents and adults to support clinicians in their therapeutic decision-making process. The most recent acne guidelines were published in 2016, and the approach to care and the therapeutic landscape of acne have evolved since that time. The Acne Management Consensus Roundtable was convened in 2022 to discuss unmet needs in the management of acne. The main focus of the meeting was the role of androgens in acne pathology; the evaluation of clascoterone, the first topical anti-androgen that specifically addresses sebum production in acne; and the identification of the place of clascoterone in therapy. Clascoterone was approved by the US Food and Drug Administration for the treatment of acne in patients 12 years and older in 2020. This report aims to highlight important limitations of the 2016 AAD treatment guidelines and to familiarize practitioners with clascoterone and its indication, efficacy and safety profile, and potential use across diverse patient populations. With its new mechanism of action, clascoterone may be able to fulfill important unmet needs in acne treatment. Baldwin H, Farberg AS, Frey C, et al. Unmet needs in the management of acne vulgaris: a consensus statement. J Drugs Dermatol. 2023;22(6):582-587. doi:10.36849/JDD.7587.
Topics: Adult; Adolescent; Humans; Acne Vulgaris; Propionates; Cortodoxone; Sebum; Treatment Outcome
PubMed: 37276154
DOI: 10.36849/JDD.7587 -
Cutis Jul 2020Acne vulgaris is one of the most common dermatologic diseases, ranging from comedonal or inflammatory papules to large, painful, disfiguring cysts. Numerous treatment... (Review)
Review
Acne vulgaris is one of the most common dermatologic diseases, ranging from comedonal or inflammatory papules to large, painful, disfiguring cysts. Numerous treatment approaches are available, each with their own risks and benefits that must be weighed when selecting the best option for an individual patient. Active-duty military servicemembers face additional levels of complexity when pursuing acne therapy. Untreated acne may interfere with their assigned duties, while various therapies also may limit their medical readiness and fitness for duty. We present a review of various acne treatment modalities with a focus on the military population. Additionally, we present a case in which the pulsed dye laser (PDL) was successfully used to treat inflammatory acne in an active-duty servicemember to highlight the use of PDL as an available and effective treatment option for acne in this population.
Topics: Acne Vulgaris; Dermatologic Agents; Humans; Lasers, Dye; Military Personnel; Treatment Outcome
PubMed: 32915930
DOI: 10.12788/cutis.0057 -
Annales de Dermatologie Et de... Mar 2018
Review
Topics: Acne Vulgaris; Dermatitis, Seborrheic; Facial Dermatoses; Humans; Rosacea
PubMed: 29429583
DOI: 10.1016/j.annder.2018.01.012 -
Der Hautarzt; Zeitschrift Fur... Feb 2017Acne and rosacea are common chronic inflammatory skin diseases. During pregnancy these skin disorders may become aggravated, in rare cases occurring for the first time.... (Review)
Review
Acne and rosacea are common chronic inflammatory skin diseases. During pregnancy these skin disorders may become aggravated, in rare cases occurring for the first time. There are no data available for rosacea and little data for acne concerning the course of these skin disorders during pregnancy. Up to 42% of the pregnant women suffer from acne. In 90% of these women the disease existed before pregnancy. In 1/3, however, acne relapsed during pregnancy after a prior disease-free period. In 60% acne deteriorated during pregnancy. Randomized controlled trials for the treatment of acne or rosacea during pregnancy do not exist. In this article the recommendations of current guidelines are modified, so that effective treatments can be recommended without harming the embryo or fetus.
Topics: Acne Vulgaris; Dermatologic Agents; Dermatology; Evidence-Based Medicine; Female; Germany; Humans; Medical Oncology; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Rosacea; Treatment Outcome
PubMed: 28070633
DOI: 10.1007/s00105-016-3918-8 -
Journal of Cutaneous Medicine and... 2022
Topics: Acne Vulgaris; Humans; Isotretinoin
PubMed: 34498501
DOI: 10.1177/12034754211045379 -
Obstetrics and Gynecology May 2022
Topics: Acne Vulgaris; Contraceptives, Oral, Hormonal; Female; Humans; Intrauterine Devices; Intrauterine Devices, Medicated
PubMed: 35576353
DOI: 10.1097/AOG.0000000000004765 -
The British Journal of Dermatology Oct 2023Acne can create a significant burden for people of all ages. However, the psychological consequences might often be overlooked. This review comments on recent evidence... (Review)
Review
Acne can create a significant burden for people of all ages. However, the psychological consequences might often be overlooked. This review comments on recent evidence in the field of psychodermatology, to highlight the importance of considering a person's mental health in the treatment of acne. A range of presenting issues are discussed, and cases of underserved patients needing additional considerations are highlighted. This article considers how the psychological sequelae can contribute to the pathogenesis of acne, and discusses how psychotherapeutic approaches can be of benefit to people experiencing appearance-related distress. Importantly, attention is paid to the need for clinicians to assess a patient's wellbeing alongside their physical symptoms. In doing this, early intervention can be facilitated if psychological comorbidities are present, with referral to appropriate specialist services, where available. To improve treatment outcomes, the skin and the mind must be addressed together in a multidisciplinary approach to dermatology care.
Topics: Humans; Acne Vulgaris; Mental Health; Referral and Consultation
PubMed: 37903071
DOI: 10.1093/bjd/ljad251