-
JMIR Research Protocols Jun 2024Curcuminoids and acupressure have beneficial effects in reducing pain and inflammation in patients with osteoarthritis. However, only a few clinical trials are... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
Curcuminoids and acupressure have beneficial effects in reducing pain and inflammation in patients with osteoarthritis. However, only a few clinical trials are investigating biomarkers to prove this objectively.
OBJECTIVE
This study aims to investigate the effect of acupressure and curcuminoids on inflammatory markers and pain in older people with osteoarthritis genu.
METHODS
A randomized controlled trial (RCT) was conducted among older people with osteoarthritis. All participants were randomized to a group that received 30 mg of curcuminoids in turmeric extract capsules and acupressure (group 1) or a group that received a placebo and sham acupressure (group 2) for 3 weeks.
RESULTS
The study was approved by the research ethics board; ClinicalTrials.gov reviewed this protocol. The extracts were manufactured from May 2023 to June 2023. Participant recruitment was conducted in September and October 2023; a total of 72 participants aged 60 years or older participated, of whom 75% (n=54) were female. Data were analyzed in April 2024, and dissemination of results is expected by the end of 2024.
CONCLUSIONS
Primary outcomes were assessed at baseline and after the intervention. Relationships were assessed with inflammatory markers, endorphin hormones, and blood level of cycloxygenase-2 hormone. Additionally, secondary outcomes included pain, ability to perform activities of daily living, and quality of life. The beneficial effects that may be found in this trial may be exceptionally relevant in clinical practice, justifying this scientific inquiry. The benefits of herbs and acupressure can be helpful as additional options in treating inflammation and pain in patients with osteoarthritis.
TRIAL REGISTRATION
ClinicalTrials.gov NCT06105840; https://clinicaltrials.gov/study/NCT06105840.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID)
DERR1-10.2196/54970.
Topics: Humans; Female; Aged; Male; Osteoarthritis; Acupressure; Inflammation; Middle Aged; Pain Management; Combined Modality Therapy
PubMed: 38771152
DOI: 10.2196/54970 -
Iranian Journal of Kidney Diseases Mar 2018Uremic pruritus is characterized by an uncomfortable and unlimited sensation which leads to scratch, which strongly reduces the quality of life. Pruritus is a common... (Meta-Analysis)
Meta-Analysis Review
INTRODUCTION
Uremic pruritus is characterized by an uncomfortable and unlimited sensation which leads to scratch, which strongly reduces the quality of life. Pruritus is a common symptom in patients with end-stage renal disease. Various clinical trial studies have examined the effects of acupuncture and acupressure on treatment of uremic pruritus. This systematic review meta-analysis aimed to evaluate the effectiveness based on published studies.
MATERIALS AND METHODS
An electronic literature search was conducted to identify appropriate trial studies. The results for continuous outcomes were presented as weighted mean difference, with 95% confidence intervals.
RESULTS
A total of 5 articles, including 6 trials, were enrolled in this systematic review. Only 3 of the six trial studies used a visual analogue scale score for assessing pruritus and acupressure for intervention regime, which were considered for meta-analysis. The combined results showed that acupuncture or acupressure was effective in treatment of uremic pruritus (pooled mean difference, -1.994; 95% confidence interval, -2.544 to -1.445).
CONCLUSIONS
This study confirms that using acupuncture and acupressure is effective in treatment of uremic pruritus. However, further vigorous studies are needed to verify these findings.
Topics: Acupressure; Acupuncture Points; Acupuncture Therapy; Adult; Chi-Square Distribution; Female; Humans; Male; Middle Aged; Pruritus; Quality of Life; Risk Factors; Treatment Outcome; Uremia
PubMed: 29507269
DOI: No ID Found -
Archives of Gynecology and Obstetrics Apr 2024The purpose of this study was to evaluate the efficacy and safety of acupressure on nausea and vomiting during pregnancy. (Meta-Analysis)
Meta-Analysis Review
OBJECTIVE
The purpose of this study was to evaluate the efficacy and safety of acupressure on nausea and vomiting during pregnancy.
METHODS
PubMed, Embase, Springer, Web of Science, and the Cochrane Library were searched for all randomized controlled trials (RCT) of treating nausea and vomiting during pregnancy by acupressure from the inception date of database to July 31st, 2023. Study selection, data extraction, and risk of bias assessment were conducted independently by researchers. The methodological quality of included studies was evaluated by the Cochrane Collaboration's bias risk assessment tool, meta-analysis by Stata 17.0 software, and publication bias by Begg's test.
RESULTS
A total of 11 RCTs involving 1378 pregnant women were included in this review, which was assessed to be moderate quality. 10 RCTs involving 1298 pregnant women were assessed for the meta-analysis. The results revealed that acupressure showed significant difference on improvement in symptom score compared with sham acupressure (pooled MD, - 1.33; 95%CI [- 2.06, - 0.61]; P < 0.001) or control group (pooled MD, - 0.73; 95%CI [- 1.08, - 0.39]; P < 0.001), and incidence of effective rate compared with sham acupressure group (pooled RR, 1.78; 95%CI [1.03, 3.07]; P = 0.039). However, no statistical significance was found between acupressure and control group (pooled RR, 4.53; 95%CI [0.67, 30.48]; P = 0.120) on effective rate. On comparing acupressure with sham acupressure, there was no beneficial effect on preventing nausea and vomiting during pregnancy (pooled RR, 0.83; 95%CI [0.50, 1.38]; P = 0.476), shortening the duration of hospital stay (pooled MD, - 0.78; 95%CI [- 1.98, 0.41]; P = 0.199) and improving patient satisfaction (pooled RR, 1.36; 95%CI [0.47, 3.91]; P = 0.570). Begg's test did not reveal any publication bias. Only one RCT reported minimal acupressure-related adverse events.
CONCLUSION
Acupressure may have potential favorable or encouraging effect on treating nausea and vomiting during pregnancy, but strong supportive data are not yet available. Well-designed and large-scale RCTs should be conducted for assessing and confirming the efficacy and safety of acupressure in nausea and vomiting during pregnancy.
Topics: Female; Pregnancy; Humans; Acupressure; Randomized Controlled Trials as Topic; Vomiting; Nausea
PubMed: 38104041
DOI: 10.1007/s00404-023-07313-0 -
European Journal of Anaesthesiology Aug 2019
Topics: Acupressure; Humans; Quality of Life; Treatment Outcome
PubMed: 31274543
DOI: 10.1097/EJA.0000000000001031 -
Complementary Therapies in Medicine Feb 2015To assess the efficacy and safety of self-administered acupressure to alleviate symptoms of various health problems, including allergic disease, cancer, respiratory... (Review)
Review
OBJECTIVES
To assess the efficacy and safety of self-administered acupressure to alleviate symptoms of various health problems, including allergic disease, cancer, respiratory disease, dysmenorrhea, perceived stress, insomnia, and sleep disturbances.
METHODS
We searched core, Korean, Chinese, and Japanese databases, including Ovid-MEDLINE, Ovid-EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), the Cumulative Index to Nursing and Allied Health Literature (CINAHL), six representative electronic Korean medical databases, China National Knowledge Infrastructure (CNKI), and Japan Science and Technology Information Aggregator (J-STAGE). We included randomized controlled trials (RCTs) and quasi-RCTs that examined disease-specific effects or symptom relief, adverse reactions, and quality-of-life (QOL) for self-administered acupressure. Data collection and assessment of the methodological quality of the included studies were conducted by two independent reviewers.
RESULTS
Eight RCTs and two quasi-RCTs showed positive effects and safety of self-acupressure therapy in clinically diverse populations. Quality assessment revealed moderate quality for the RCTs, with 50% or more of the trials assessed as presenting a low risk of bias in seven domains. All of the selected 10 studies reported positive effects for primary outcomes of self-acupressure therapy for symptom management, including significant improvements in symptom scores in allergic disease, nausea and vomiting in cancer, symptom scores in respiratory disease, pain symptoms in dysmenorrhea, and stress/fatigue scores and sleep disturbances in healthy people.
CONCLUSIONS
Our findings suggest that self-administered acupressure shows promise to alleviate the symptoms of various health problems. Therefore, further research with larger samples and methodologically well-designed RCTs is required to establish the efficacy of self-administered acupressure.
Topics: Acupressure; Disease Management; Humans; Quality of Life; Self Care
PubMed: 25637155
DOI: 10.1016/j.ctim.2014.11.002 -
Pain Management Nursing : Official... Dec 2022Acupuncture and acupressure are not being systematically used in the management of postoperative nausea and vomiting and pain, despite being included in the guidelines.
BACKGROUND
Acupuncture and acupressure are not being systematically used in the management of postoperative nausea and vomiting and pain, despite being included in the guidelines.
AIM
To examine the beliefs, attitudes, and knowledge of Australian nurses/midwives and doctors toward the perioperative use of AA for the management of postoperative nausea and vomiting and pain; to explore the barriers and enablers influencing acupuncture and acupressure integration into hospital setting.
METHODS
A mixed-mode approach was undertaken for data collection. An online approach was used to recruit respondents from Australian College of Perioperative Nurses. Three hospitals from three different Australian states were selected via convenience sampling.
RESULTS
A total of 421 usable surveys were included in data analysis. The respondents comprised 14.3% doctors and 72.9% nurses/midwives. Overall, 69.4% were female, 85% were trained in Australia with 35% and 51.4% having knowledge or personal exposure to AA in general respectively. Over 60% of the respondents agreed AA should be routinely integrated into perioperative care, and over 80% would recommend AA to their patients if it was provided at their hospital, and, 75% would be willing to receive further education. The three main reported barriers included: perceived lack of scientific evidence (80.9%), unavailability of credentialed provider (77.2%) and lack of reimbursement (60.4%).
CONCLUSIONS
Positive attitudes are reported by Australian doctors and nurses toward AA. This is despite of low levels of knowledge or personal exposure to AA. Further studies are required to explore the implementation of barriers and address respondent calls for further education.
Topics: Humans; Female; Male; Acupressure; Postoperative Nausea and Vomiting; Australia; Attitude of Health Personnel; Acupuncture Therapy; Surveys and Questionnaires; Perioperative Care; Nurses; Pain
PubMed: 36153218
DOI: 10.1016/j.pmn.2022.08.008 -
International Journal of Gynaecology... Oct 2016Acupressure is increasing in popularity as an alternative treatment in obstetrics and gynecology. (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Acupressure is increasing in popularity as an alternative treatment in obstetrics and gynecology.
OBJECTIVES
To summarize and assess evidence regarding the effects of acupressure on duration of labor and mode of delivery.
SEARCH STRATEGY
Four major databases and Google Scholar were searched using terms related to labor and acupressure, without language restrictions, up to November 2015.
SELECTION CRITERIA
Randomized controlled trials were included if they examined the effect of acupressure at any acupoint during childbirth on duration of labor and/or mode of delivery.
DATA COLLECTION AND ANALYSIS
Two reviewers independently extracted data. The outcome measures were duration of labor and mode of delivery. Random-effects models were used to pool results.
MAIN RESULTS
Thirteen studies were included in meta-analyses. Acupressure increased the chance of vaginal delivery when compared with placebo/no intervention (odds ratio [OR] 2.329, 95% confidence interval [CI] 1.348-4.024, P=0.002; risk difference [RD] 8.9%, 95% CI 2.7%-15.0%, P=0.005). Acupressure decreased the duration of the active phase by 1.310 hours (95% CI -1.738 to -0.882; P<0.001) and the second stage of labor by 5.808 minutes (95% CI -1.615 to -0.807; P<0.001).
CONCLUSIONS
Acupressure could have a role in reducing the rate of cesarean delivery and decreasing the duration of labor in parturient women. However, there is a need for more reliable randomized controlled trials.
Topics: Acupressure; Cesarean Section; Female; Humans; Labor Stage, First; Labor Stage, Second; Parturition; Pregnancy; Time Factors
PubMed: 27569023
DOI: 10.1016/j.ijgo.2016.04.017 -
Oncology Nursing Forum Nov 2014To critically examine the evidence for acupuncture and acupressure in the management of cancer-related fatigue (CRF) in adult patients with cancer. (Review)
Review
PURPOSE/OBJECTIVES
To critically examine the evidence for acupuncture and acupressure in the management of cancer-related fatigue (CRF) in adult patients with cancer.
DATA SOURCES
18 databases were searched for randomized, controlled trials published in English and Chinese through April 2014.
DATA SYNTHESIS
Given the heterogeneity of data, meta-analysis was not conducted. A six-step thematic analysis method was used to synthesize the results.
CONCLUSIONS
Although results are inconclusive, acupuncture and acupressure tend to be effective in relieving CRF, with the former producing a greater improvement. Future research is recommended to contribute further evidence.
IMPLICATIONS FOR NURSING
Nurses should know about the relative effectiveness of acupuncture and acupressure in the management of CRF to educate and support their patients.
Topics: Acupressure; Acupuncture Therapy; Fatigue; Humans; Neoplasms
PubMed: 25355016
DOI: 10.1188/14.ONF.581-592 -
Journal of Special Operations Medicine... 2016The series objective is to review various clinical conditions/ presentations, including the latest evidence on management, and to dispel common myths. In the process,... (Review)
Review
The series objective is to review various clinical conditions/ presentations, including the latest evidence on management, and to dispel common myths. In the process, core knowledge and management principles are enhanced. A clinical case will be presented. Cases will be drawn from real life but phrased in a context that is applicable to the Special Operations Forces (SOF) or tactical emergency medical support (TEMS) environment. Details will be presented in such a way that the reader can follow along and identify how they would manage the case clinically depending on their experience and environment situation. Commentary will be provided by currently serving military medical technicians. The medics and author will draw on their SOF experience to communicate relevant clinical concepts pertinent to different operational environments including SOF and TEMS. Commentary and input from active special op.
Topics: Acupressure; Antiemetics; Cholinergic Antagonists; Dopamine Antagonists; Emergency Medical Technicians; Histamine Antagonists; Humans; Meclizine; Metoclopramide; Military Personnel; Motion Sickness; Ondansetron; Promethazine; Scopolamine
PubMed: 27450607
DOI: No ID Found -
Clinical Rehabilitation Mar 2022Knee osteoarthritis is a prevalent degenerative joint disease and seriously affects the athletic abilities of middle-aged and elderly patients. Acupressure is a... (Randomized Controlled Trial)
Randomized Controlled Trial
OBJECTIVE
Knee osteoarthritis is a prevalent degenerative joint disease and seriously affects the athletic abilities of middle-aged and elderly patients. Acupressure is a traditional non-pharmacological intervention that promotes blood circulation and muscle activity. Self-administrated acupressure and exercise can be potential management for knee osteoarthritis.
DESIGN
It is a randomized and controlled trial for knee osteoarthritis self-treatment.
SETTINGS
Cangzhou Hospital.
INTERVENTIONS
221 patients with knee osteoarthritis were recruited and randomly divided into 4 groups: control group ( = 55), exercise group ( = 56), acupressure group ( = 55) and exercise & acupressure group ( = 55). In the first eight weeks, corresponding training courses were provided to different groups of patients. The patients were asked to carry out their own corresponding interventions for 16 weeks. The patient's condition was evaluated in the sixteenth week.
MAIN MEASURES
The Western Ontario and McMaster Universities global scores of knee osteoarthritis patients were assessed at the 8th and 16th week of our trial.
RESULTS
Self-administered acupressure and exercise significantly decreased visual analogue scale (3.75 ± 1.89 versus 2.93 ± 1.73, < 0.05), pain (7.6 ± 2.8 versus 4.8 ± 2.7, < 0.05), stiffness (3.75 ± 1.89 versus 2.93 ± 1.73, < 0.05) at the 16th week ( < 0.05) in patients with knee osteoarthritis compared to other intervention. The combination of acupressure and exercise also improved the range of motion (114.4 ± 11.5 versus 120.4 ± 11.9, < 0.05) and walk speed (1.48 ± 0.48 versus 1.76 ± 0.50, < 0.05) of osteoarthritis patients ( < 0.05).
CONCLUSION
Self-administrated exercise and acupressure alleviate the arthritic symptoms (swelling, pain, joint dysfunction and joint deformities) and improve the joint functions, supporting its potential use in the clinical management for osteoarthritis.
Topics: Acupressure; Aged; Exercise Therapy; Humans; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Range of Motion, Articular; Treatment Outcome
PubMed: 34658285
DOI: 10.1177/02692155211049155