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Pathogens (Basel, Switzerland) Oct 2023Angiostrongyliasis is a parasitic disease caused by larvae of the genus , with and being the two main species causing diseases in humans [...].
Angiostrongyliasis is a parasitic disease caused by larvae of the genus , with and being the two main species causing diseases in humans [...].
PubMed: 37887730
DOI: 10.3390/pathogens12101214 -
Trends in Parasitology Dec 2021
Topics: Angiostrongylus; Animals; Strongylida Infections
PubMed: 34420866
DOI: 10.1016/j.pt.2021.08.002 -
Parasitology Feb 2021
Topics: Angiostrongylus cantonensis; Animals; Humans; Meningoencephalitis; Strongylida Infections
PubMed: 33315004
DOI: 10.1017/S003118202000236X -
Biomedica : Revista Del Instituto... Jun 2019Introduction: Angiostrongylus cantonensis is a serious public health problem and is widely distributed in the country. When the parasite infects the snails, it becomes... (Review)
Review
Introduction: Angiostrongylus cantonensis is a serious public health problem and is widely distributed in the country. When the parasite infects the snails, it becomes deeply embedded in their interior and accidentally, it can infect people and other mammals. Objective: To establish the geographical distribution of A. cantonensis intermediate hosts (Achatina fulica) and definitive hosts (Rattus spp.) in Ecuador from 2014 to 2017. Materials and methods: We collected 2,908 A. fulica specimens in 16 provinces using the capture method per unit of effort for 30 minutes. We captured 211 hosts of which 20 were Rattus rattus and 191 R. norvegicus. The specimens were transported to the Instituto Nacional de Salud Pública e Investigación in Guayaquil where the larvae L3 were identified and counted in the tissues of the snail, which were then inoculated in laboratory rats to reproduce the life cycle. In the rodents, the brains, hearts, lung arteries and lungs were dissected, and the parasites were identified by taxonomic morphology. Results: Of the snails harvested, 441 were positive for A. cantonensis (15.2%) and a total of 6,166 L3 larvae were found; 77 (36.5%) specimens of Rattus spp., were infected with A. cantonensis and a total of 220 parasites (L4-L5 larvae and adult worms) were collected. Conclusions: We confirmed the presence of A. cantonensis in several provinces, which ratifies the endemic nature of this zoonosis in the national territory. Rattus spp. specimens constitute the definitive hosts of the parasite, which together with the presence of intermediate hosts, indicates the zoonotic potential of this parasitic infection.
Topics: Angiostrongylus cantonensis; Animals; Animals, Wild; Disease Reservoirs; Disease Vectors; Ecuador; Female; Geography, Medical; Introduced Species; Larva; Life Cycle Stages; Rats; Rodent Diseases; Snails; Species Specificity; Strongylida Infections; Zoonoses
PubMed: 31529823
DOI: 10.7705/biomedica.v39i3.4387 -
Parasitology Nov 2022The rat lungworm is globally known to be the cause of oeosinophilic meningitis in humans. Another congener, , is closely related to and has been described as a...
The rat lungworm is globally known to be the cause of oeosinophilic meningitis in humans. Another congener, , is closely related to and has been described as a potential human pathogenic parasite. These 2 worms are similar in terms of life cycle, host range and morphological and genetic information. However, there are limited studies about their genetic diversity based on the 66-kDa protein-encoding gene. The objective of this study was to explore the 66-kDa protein sequence variation of and collected from Thailand. Two adult and 53 third-stage larval specimens of from 4 geographic locations in Thailand were molecularly identified using the 66-kDa protein gene. The phylogenetic trees (Bayesian inference tree and maximum-likelihood tree) showed that formed a monophyletic clade with a clear separation between and . The genetic distance between and varies from 0.82 to 2.86%, with a total of 16 variable sites. The analysis of genetic diversity revealed 1 and 5 new haplotypes of and , respectively, and showed genetic differences between the populations of and . The haplotype networks of and populations in Thailand are similar to those of populations in some countries, indicating the range expansion of genomic origin between populations in different areas. In conclusion, the 66-kDa protein gene was a good genetic marker for studying genetic diversity and discriminating between and .
PubMed: 36472511
DOI: 10.1017/S0031182022001573 -
Vector Borne and Zoonotic Diseases... Mar 2015Despite an apparent increase in cases of angiostrongyliasis in humans and animals in Australia, the epidemiology of infection with the two species of Angiostrongylus... (Review)
Review
Despite an apparent increase in cases of angiostrongyliasis in humans and animals in Australia, the epidemiology of infection with the two species of Angiostrongylus that co-exist in this country, namely A. cantonensis and A. mackerrasae, is poorly understood. This knowledge gap is particularly important with respect to A. mackerrasae, a species evidently native to Australia, as its ability to cause disease in humans is unknown. Likewise, there is little information on the roles of native and introduced species of rodents and molluscs as hosts of Angiostrongylus species in Australia. This review focuses on the gaps in the knowledge about the two species, highlighting the need for epidemiological and pathogenesis studies on the native lungworm A. mackerrasae.
Topics: Angiostrongylus; Animals; Australia; Central Nervous System Helminthiasis; Communicable Diseases, Emerging; Strongylida Infections
PubMed: 25793473
DOI: 10.1089/vbz.2014.1622 -
Research in Veterinary Science Mar 2021Human angiostrongyliasis is an important foodborne zoonosis, caused by the infection with Angiostrongylus costaricensis and Angiostrongylus cantonensis. These two... (Review)
Review
Human angiostrongyliasis is an important foodborne zoonosis, caused by the infection with Angiostrongylus costaricensis and Angiostrongylus cantonensis. These two species have a significant public health impact in different areas of the world. Angiostrongyliasis is re-emerging and expanding to urban settings rising significant concerns regarding the control of these infections. This review focuses on aspects such as life cycle, epidemiology, clinical manifestations, diagnostics, food safety and control of illness caused especially by A. cantonensis.
Topics: Angiostrongylus; Animals; Anthelmintics; Global Health; Humans; Strongylida Infections
PubMed: 33160683
DOI: 10.1016/j.rvsc.2020.10.023 -
Journal of the American Veterinary... Mar 2018
Topics: Angiostrongylus cantonensis; Animals; Animals, Zoo; Autopsy; Chiroptera; Diagnosis, Differential; Female; Hemorrhage; Meningoencephalitis; Strongylida Infections
PubMed: 29461163
DOI: 10.2460/javma.252.5.545 -
Journal of Helminthology Jul 2019This catalogue is concerned with the closely related angiostrongylid genera Angiostrongylus, Gallegostrongylus, Rodentocaulus and Stefanskostrongylus. Three species,... (Review)
Review
Annotated catalogue of species of Angiostrongylus and the related genera Gallegostrongylus, Rodentocaulus and Stefanskostrongylus (Nematoda: Metastrongyloidea, Angiostrongylidae).
This catalogue is concerned with the closely related angiostrongylid genera Angiostrongylus, Gallegostrongylus, Rodentocaulus and Stefanskostrongylus. Three species, Angiostrongylus cantonensis, A. costaricensis and A. vasorum, have attracted most attention because of their importance in human and domestic animal disease. Many of the remaining species are poorly known and the number of valid taxa is unclear. The catalogue lists all nomenclaturally available and unavailable genus-group and species-group names that have been applied to the above genera and the species included in them, indicating their current nomenclatural status and providing the rigorous nomenclatural basis for future work. The catalogue lists 14 published and nomenclaturally available genus-group names, with the above four treated as valid, the other ten being junior synonyms. There are 42 published species-group names: 36 are valid, two are junior synonyms, four are nomenclaturally unavailable. One additional species, described in Chabaudistrongylus (synonym of Angiostrongylus), is listed as incertae sedis in Angiostrongylidae. Also listed are two unpublished collection names. The catalogue provides bibliographic details for all published names, and for available names provides locations of type material, details of type localities, geographic distributions and details of type and other hosts, both definitive and intermediate, to the extent known. The catalogue is a work of nomenclature, not a revisionary taxonomic work. No new names or new combinations are proposed. The apparently new family-group synonymy of Cardionematinae with Angiostrongylidae is introduced, as are four genus-group synonymies, three with Angiostrongylus and one with Stefaskostrongylus.
Topics: Angiostrongylus; Animals; Animals, Domestic; Catalogs as Topic; Humans; Phylogeny; Terminology as Topic
PubMed: 31064435
DOI: 10.1017/S0022149X19000270 -
International Medical Case Reports... 2021To report the patient with subretinal larva.
PURPOSE
To report the patient with subretinal larva.
METHODS
Retrospective, observational case report.
RESULTS
A 47-year-old Thai woman had eosinophilic meningitis. One week after the onset of a headache, blurred vision developed in her right eye. Ocular examination of the right eye showed larva in the subretinal space in the inferotemporal quadrant and macular edema. Although serum analysis for was negative, the larva can be identified by its characteristic appearance. Blood eosinophilia and cerebrospinal fluid eosinophilia were presented. Focal laser photocoagulation was applied to the retina, and the patient also received anti-helminthic and oral corticosteroid drugs. The vision did not recover. Ultimately, the retina became atrophic. The dead larva remained at the same site at which it was observed. No further larval migration occurred after treatment.
CONCLUSION
larva can damage the retinal layer despite its eradication and no further migration. After its death, the inflammation persisted either as the result of toxin secretion or an immune responsiveness. Administration of local anti-inflammatory drugs such as corticosteroids or any anti-vascular endothelial growth factor injection should be considered.
PubMed: 34744462
DOI: 10.2147/IMCRJ.S324286