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Drug Metabolism Reviews May 2020Nano-hydroxyapatite (nano-HA) is a material with multiple uses due to its biocompatibility and its resemblance to the nonorganic bone structure. It is used in various...
Nano-hydroxyapatite (nano-HA) is a material with multiple uses due to its biocompatibility and its resemblance to the nonorganic bone structure. It is used in various dental domains such as implantology, surgery, periodontology, esthetics and prevention. The aim of this study is to provide a wide understanding of nano-HA and to promote treatments based on nanomaterials in dentistry. A search in two data bases, Scopus, and PubMED, was conducted over a 5 years period. We chose a 5 years period because this revealed the most recent published studies with the key words 'nano-HA' and 'dentistry'. A number of 32 studies were included in this systematic review. In implantology the main use of nano-HA was as a coating material for titanium implants and its effect was assessed in the matter of osteointegration and inflammatory response as well as antibacterial activity. In tissue engineering the use of nano-HA was directed to surgery and periodontology and this material was assessed mainly as a grafting material. In esthetics and prevention its use was mainly focused on dentinal hypersensitivity treatment, remineralizing potential and as bleaching co-agent. Nano-HA is a relatively novel material with outstanding physical, chemical, mechanical and biological properties that makes it suitable for multiple interventions. It outperformed most of the classic materials used in implantology and surgery but it should be further investigated for bone engineering and caries therapy.
Topics: Animals; Dental Materials; Dental Prosthesis; Humans; Hydroxyapatites; Nanoparticles
PubMed: 32393070
DOI: 10.1080/03602532.2020.1758713 -
Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi... Jun 2020Bulk-fill composite resin are simple to operate, and they reduce polymerization shrinkage and microleakage compare to traditional resin-based composites. However, their... (Review)
Review
Bulk-fill composite resin are simple to operate, and they reduce polymerization shrinkage and microleakage compare to traditional resin-based composites. However, their clinical application could be affected by numerous factors, such as the material itself, light curing, placement techniques, storage condition, and preheating. This review aimed to summarize the definitions, classifications, indications, clinical properties, and influencing factors of the clinical application of bulk-fill resin-based composites and discuss the ways to improve their clinical effectiveness.
Topics: Composite Resins; Dental Materials; Materials Testing; Polymerization; Surface Properties
PubMed: 32573127
DOI: 10.7518/hxkq.2020.03.001 -
Dental Clinics of North America Jan 2021In the past, the only way to replace missing teeth was to have a removable appliance. However, these days, dental implants are commonly being used to replace missing... (Review)
Review
In the past, the only way to replace missing teeth was to have a removable appliance. However, these days, dental implants are commonly being used to replace missing teeth. The dental implants are improving as a result of new technological and scientific advances. Different materials have been used in the past for dental implants such as lead, stainless steel, and gold. Currently, the focus is on using Roxolid, surface-modified titanium implants, and zirconia. These materials have superior esthetic and functional characteristics for dental implants.
Topics: Dental Implants; Dental Materials; Esthetics, Dental; Humans; Materials Science; Titanium; Zirconium
PubMed: 33213717
DOI: 10.1016/j.cden.2020.09.006 -
The British Journal of Dermatology May 2024
Topics: Humans; Dermatitis, Allergic Contact; Female; Male; Adult; Middle Aged; Dental Materials; Patch Tests; Aged
PubMed: 38758061
DOI: 10.1093/bjd/ljae160 -
Journal of Dental Research Oct 2023Despite its reputation as the most widely used restorative dental material currently, resin-based materials have acknowledged shortcomings. As most systematic survival... (Review)
Review
Despite its reputation as the most widely used restorative dental material currently, resin-based materials have acknowledged shortcomings. As most systematic survival studies of resin composites and dental adhesives indicate, secondary caries is the foremost reason for resin-based restoration failure and life span reduction. In subjects with high caries risk, the microbial community dominated by acidogenic and acid-tolerant bacteria triggers acid-induced deterioration of the bonding interface and/or bulk material and mineral loss around the restorations. In addition, resin-based materials undergo biodegradation in the oral cavity. As a result, the past decades have seen exponential growth in developing restorative dental materials for antimicrobial applications addressing secondary caries prevention and progression. Currently, the main challenge of bioactive resin development is the identification of efficient and safe anticaries agents that are detrimental free to final material properties and show satisfactory long-term performance and favorable clinical translation. This review centers on the continuous efforts to formulate novel bioactive resins employing 1 or multiple agents to enhance the antibiofilm efficacy or achieve multiple functionalities, such as remineralization and antimicrobial activity antidegradation. We present a comprehensive synthesis of the constraints and challenges encountered in the formulation process, the clinical performance-related prerequisites, the materials' intended applicability, and the current advancements in clinical implementation. Moreover, we identify crucial vulnerabilities that arise during the development of dental materials, including particle aggregation, alterations in color, susceptibility to hydrolysis, and loss of physicomechanical core properties of the targeted materials.
Topics: Humans; Dental Restoration, Permanent; Dental Materials; Composite Resins; Dental Caries; Dentistry; Anti-Infective Agents
PubMed: 37555431
DOI: 10.1177/00220345231182357 -
British Dental Journal May 2022With the phasing down of dental amalgam use in response to the Minamata Convention, it is likely that resin-based composite restoratives will be the dental material of... (Review)
Review
With the phasing down of dental amalgam use in response to the Minamata Convention, it is likely that resin-based composite restoratives will be the dental material of choice for the direct restoration of compromised dentition in the UK, at least for the foreseeable future. The current materials have a finite lifespan, with failures predominately due to either secondary caries or fracture. Consequently, there is considerable in vitro research reported each year with the intention of producing improved materials. This review describes the recent research in materials designed to have low polymerisation shrinkage and increased mechanical properties. Also described is research into materials that are either antimicrobial or are designed to release ions into the surrounding oral environment, with the aim of stimulating remineralisation of the surrounding dental tissues. It is hoped that by describing this recent research, clinicians will be able to gain some understanding of the current research that will potentially lead to new products that they can use to improve patient treatment in the future.
Topics: Composite Resins; Dental Amalgam; Dental Caries; Dental Materials; Dental Restoration, Permanent; Humans
PubMed: 35562465
DOI: 10.1038/s41415-022-4240-8 -
British Dental Journal May 2022Dental materials can cause reactions to the oral mucosa and present to the general dental practitioner. These are often referred to as 'allergies' but are frequently...
Dental materials can cause reactions to the oral mucosa and present to the general dental practitioner. These are often referred to as 'allergies' but are frequently lichenoid reactions. Most of these are related to dental amalgam restorations and can be remedied by replacing the restoration with another suitable material. Other metals, including gold, palladium, nickel and chrome, have also been reported to trigger mucosal changes. Less commonly, issues arise from other restorative materials, including denture acrylics, composites and glass polyalkenoates. Reactions are also reported due to endodontic and sealing materials. It is unclear what role skin 'patch' testing has in managing dental material allergies. This article aims to give the practitioner a clearer picture of dental material allergy issues and how they should be approached in primary dental practice.
Topics: Dental Amalgam; Dental Materials; Dental Restoration, Permanent; Dentists; Humans; Hypersensitivity; Patch Tests; Professional Role
PubMed: 35562454
DOI: 10.1038/s41415-022-4195-9 -
Journal of Biomedical Materials... Feb 2017The global market for dental materials is predicted to exceed 10 billion dollars by 2020. The main drivers for this growth are easing the workflow of dentists and... (Review)
Review
The global market for dental materials is predicted to exceed 10 billion dollars by 2020. The main drivers for this growth are easing the workflow of dentists and increasing the comfort of patients. Therefore, remarkable research projects have been conducted and are currently underway to develop improved or new dental materials with enhanced properties or that can be processed using advanced technologies, such as CAD/CAM or 3D printing. Among these materials, zirconia, glass or polymer-infiltrated ceramics, and glass-ceramics (GCs) are of great importance. Dental glass-ceramics are highly attractive because they are easy to process and have outstanding esthetics, translucency, low thermal conductivity, high strength, chemical durability, biocompatibility, wear resistance, and hardness similar to that of natural teeth, and, in certain cases, these materials are bioactive. In this review article, we divide dental GCs into the following two groups: restorative and bioactive. Most restorative dental glass-ceramics (RDGCs) are inert and biocompatible and are used in the restoration and reconstruction of teeth. Bioactive dental glass-ceramics (BDGCs) display bone-bonding ability and stimulate positive biological reactions at the material/tissue interface. BDGCs are suggested for dentin hypersensitivity treatment, implant coating, bone regeneration and periodontal therapy. Throughout this paper, we elaborate on the history, processing, properties and applications of RDGCs and BDGCs. We also report on selected papers that address promising types of dental glass-ceramics. Finally, we include trends and guidance on relevant open issues and research possibilities. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 619-639, 2017.
Topics: Ceramics; Dental Materials; Humans; Printing, Three-Dimensional
PubMed: 27701809
DOI: 10.1002/jbm.a.35923 -
Compendium of Continuing Education in... Oct 2021Today's adhesive dentistry facilitates tooth structure preservation and the use of highly esthetic materials, meeting the ever-increasing demand for minimally invasive...
Today's adhesive dentistry facilitates tooth structure preservation and the use of highly esthetic materials, meeting the ever-increasing demand for minimally invasive treatment. With proper protocols, adhesive resin bonding not only attaches direct and indirect materials, such as composite resins, ceramics, and others, to tooth structures but also reinforces the tooth and restorative material. Strong evidence shows that long-term clinical success rates of adhesive dentistry are well within the range of conventional non-adhesive, retention-based protocols. For optimal bond strengths and long-lasting clinical success, each material and tooth substrate requires specific pretreatments, bonding agents, and protocols, as this article will discuss.
Topics: Ceramics; Composite Resins; Dental Bonding; Dental Cements; Dental Materials; Esthetics, Dental; Materials Testing; Resin Cements
PubMed: 34555916
DOI: No ID Found -
American Journal of Dentistry Nov 2018To provide updated summary information about antibacterial dental materials, primarily covering the literature from 2012 through 2017. (Review)
Review
PURPOSE
To provide updated summary information about antibacterial dental materials, primarily covering the literature from 2012 through 2017.
METHODS
A key-worded search was conducted of peer-reviewed literature (Titles/Abstracts) indexed by PubMed databases, constrained to "English" and " dental" publications between the years 2012 and 2017. Key words applied to the search included: antimicrobial, antibacterial, primer, bonding agent, adhesive, cement, composite, liner, sealant, etchant, and core-build-up. Titles and abstracts of the articles returned by the search were reviewed and evaluated for appropriateness for inclusion in this review.
RESULTS
A variety of antibacterial agents have been incorporated into experimental and commercial dental restorative materials to provide antibacterial activity in dental applications. No new antibacterial compounds were introduced in this review period (2012-2017), since the last review of period of 1980-2012. Antibacterial agents include leachable compounds (e.g. benzalkonium chloride, chlorhexidine), polymerizable monomers (e.g. quaternary ammonium methacrylates), and filler particles (e.g. silver nanoparticle). During the 2012-2017 review period, many antibacterial agents were tested in experimental formulations, but only four agents (benzalkonium chloride, chlorhexidine, glutaraldehyde, and MDPB) were used in commercial products.
CLINICAL SIGNIFICANCE
Leachable antibacterial agents are the most frequently used type of antibacterial dental materials, but their efficacy may be short-lived due to their characteristic burst effect. Solid filler particles appear to be effective antibacterial agents, especially given their ability to reduce biofilm formation, but the color stability of their component metal particles is unfavorable for use in a commercial product. Polymerizable antibacterial agents (MDPB) are theoretically a good choice of material because they are very effective at killing any residual bacteria in a cavity preparation prior to polymerization, however, apart from their proven effect on reduction of biofilm formation, their long-term clinical performance is still questionable.
Topics: Anti-Bacterial Agents; Biofilms; Dental Cements; Dental Materials; Materials Testing; Metal Nanoparticles; Silver
PubMed: 31099206
DOI: No ID Found