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Viruses Jun 2022The resurgence of mumps in vaccinated adult populations has raised concerns about possible waning vaccine immunity or a potential lack of protection to the circulating... (Review)
Review
The resurgence of mumps in vaccinated adult populations has raised concerns about possible waning vaccine immunity or a potential lack of protection to the circulating strain. A number of individual studies have investigated if there are amino acid variations between the circulating wild-type strains and vaccine strains. In these studies, the HN and F mumps surface glycoproteins have been of interest, because of their role in viral infection, and because the HN protein is the target of neutralizing antibodies. Here, we summarize the single nucleotide variants and their potential effect that have been identified between mumps genotypes in the HN and F proteins.
Topics: Antibodies, Neutralizing; Glycoproteins; HN Protein; Humans; Mumps; Mumps virus
PubMed: 35746805
DOI: 10.3390/v14061335 -
The Cochrane Database of Systematic... Feb 2015Mumps is an acute, viral illness transmitted by respiratory droplets and saliva. A number of studies published in China have suggested that acupuncture is beneficial for... (Review)
Review
BACKGROUND
Mumps is an acute, viral illness transmitted by respiratory droplets and saliva. A number of studies published in China have suggested that acupuncture is beneficial for children with mumps but the literature reporting the benefits or harms of acupuncture for mumps has not been systematically reviewed.
OBJECTIVES
To determine the efficacy and safety of acupuncture for children with mumps.
SEARCH METHODS
We searched CENTRAL (2014, Issue 11), MEDLINE (1950 to November week 3, 2014), EMBASE (1974 to December 2014), CINAHL (1981 to December 2014), AMED (1985 to December 2014), the Chinese BioMedical Literature Database (CBM) (1979 to November 2014), China National Knowledge Infrastructure (CNKI) (1979 to November 2014), Chinese Technology Periodical Database (CTPD) (1989 to November 2014) and Wanfang database (1982 to November 2014). We also handsearched a number of journals (from first issue to current issue).
SELECTION CRITERIA
Randomised controlled trials comparing acupuncture with placebo acupuncture, no management, Chinese medication, Western medication or other treatments for mumps. Acupuncture included either traditional acupuncture or contemporary acupuncture, regardless of the source of stimulation (body, electro, scalp, fire, hand, fine needle, moxibustion).
DATA COLLECTION AND ANALYSIS
Two review authors independently extracted data. We identified no trials for inclusion in this updated review.
MAIN RESULTS
No study met our inclusion criteria.
AUTHORS' CONCLUSIONS
We could not reach any conclusion about the efficacy and safety of acupuncture as we identified no trials for inclusion in this review. More high-quality research is needed.
Topics: Acupuncture Therapy; Child; Drugs, Chinese Herbal; Fever; Humans; Mumps
PubMed: 25922859
DOI: 10.1002/14651858.CD008400.pub3 -
JAAPA : Official Journal of the... Dec 2021
Topics: Drug Combinations; Humans; Infant; Measles; Mumps; Rubella; Vaccination
PubMed: 34813536
DOI: 10.1097/01.JAA.0000800280.14011.81 -
Przeglad Epidemiologiczny 2022Mumps is an acute, generalized viral disease whose source of infection is the infected person. In 2003, vaccination against mumps became compulsory in Poland, performed...
INTRODUCTION
Mumps is an acute, generalized viral disease whose source of infection is the infected person. In 2003, vaccination against mumps became compulsory in Poland, performed according to a twodose scheme. The combined MMR vaccine (against measles, mumps and rubella) was introduced as part of the Protective Vaccination Program (PVP), which influenced the number of cases in Poland.
AIM
The aim of the study was to evaluate the epidemiological indicators of mumps in Poland in 2020 compared to previous years.
METHODS
The analysis of the epidemiological situation of mumps in Poland in 2020 was based on the interpretation of data from the bulletin "Infectious diseases and poisonings in Poland in 2020" and "Vaccinations in Poland in 2020".
RESULTS
In 2020, 582 cases of mumps were registered in Poland. The total incidence was 1.5 per 100,000 inhabitants and was lower compared to 2019. The highest incidence was 2.0 per 100,000 inhabitants were registered in the Świętokrzyskie Voivodeship and the lowest - 0.7 in the Dolnośląskie Voivodeship. The highest incidence (24.6/100,000) was recorded in children aged 5-9 years. The incidence of men (1.8/100,000) was higher than that of women (1.2/100,000). In 2020, 6 patients were hospitalized in Poland due to mumps, which was less than in 2019 (22 patients). The level of vaccination against mumps in children aged 3 was lower by 0.7 percentage points compared to 2019 and amounted to 91.9% across Poland.
CONCLUSIONS
In 2020, there was a decrease in the number of mumps cases compared to the previous year. The lower incidence may have been the result of a reduction in mumps virus transmission due to a change in population health behavior during the COVID-19 pandemic. Due to the epidemiological threat, the functioning of nurseries, kindergartens and schools was also temporarily suspended, which resulted in a reduction in the incidence of mumps in younger age groups, which are the main group of patients.
Topics: Child; Male; Humans; Female; Infant; Mumps; Poland; Pandemics; Mass Vaccination; Rural Population; Urban Population; Age Distribution; COVID-19; Measles-Mumps-Rubella Vaccine; Incidence
PubMed: 37017448
DOI: 10.32394/pe.76.51 -
Scandinavian Journal of Immunology Jun 2023Measles, mumps and rubella (MMR) are contagious infectious diseases that can be prevented by immunization. However, MMR infections can occur in previously immunized... (Review)
Review
Measles, mumps and rubella (MMR) are contagious infectious diseases that can be prevented by immunization. However, MMR infections can occur in previously immunized individuals. The vaccine response is, among other factors, influenced by the combined effects of many genes. This systematic review investigates the genetic influence on measles, mumps and rubella antibody responses after childhood vaccination. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), systematic literature searches were conducted in the medical databases PubMed, EMBASE and PsycINFO. Search strings were adjusted for each database. Citations were included if they measured and compared the immune response with immunogenetics after vaccination with a vaccine containing one or more of the following components: measles, mumps and/or rubella, MMR. The measure of vaccine response studied was antibodies after vaccination. Forty-eight articles were included in the final analysis. The results suggest that genetic determinants, including host genes, and single nucleotide polymorphisms in immune-related genes influence the MMR antibody responses after vaccination. Specifically, replicated associations were found between HLA, CD46, RARB, IRF9, EIF2AK2, cytokine genes and MMR vaccine-induced humoral immune responses. This knowledge can be useful in understanding and predicting immune responses and may have implications for future vaccine strategies.
Topics: Humans; Adolescent; Infant; Mumps; Measles-Mumps-Rubella Vaccine; Rubella; Measles; Antibodies, Viral
PubMed: 38157324
DOI: 10.1111/sji.13266 -
Przeglad Epidemiologiczny 2021Mumps is a highly infectious viral disease, the source of infection is an infected person. In 2003, compulsory vaccination against mumps was introduced in Poland,...
BACKGROUND
Mumps is a highly infectious viral disease, the source of infection is an infected person. In 2003, compulsory vaccination against mumps was introduced in Poland, carried out according to a two-dose schedule. The combined MMR vaccine (against measles, mumps and rubella) is used as part of the Protective Vaccination Program (PVP). Mumps vaccination has led to a significant reduction in the incidence of mumps in Poland.
AIM
The aim of the study was to evaluate the epidemiological indicators of mumps in Poland in 2019 compared to previous years.
METHODS
The analysis of the epidemiological situation of mumps in Poland in 2019 was based on the interpretation of data from the bulletin "Infectious diseases and poisonings in Poland in 2019" and "Vaccinations in Poland in 2019".
RESULTS
In 2019, 1,338 mumps cases were registered in Poland. The total incidence was 3.5 per 100,000 inhabitants and was lower compared to 2018. The highest incidence 4.6 per 100,000 inhabitants were registered in the Opolskie Voivodeship and the lowest - 2.5 in the Podkarpackie Voivodeship. The incidence was the highest among 6-year-olds and amounted to 32.3/100,000. Comparing the differences between the sexes, the incidence of men (4.1/100,000) was higher than that of women (2.9). In 2019, 22 patients were hospitalized due to mumps in Poland, which was less than in 2018 (28). The level of mumps vaccination in children at 3 years of age was lower by 0.3% compared to 2018 and amounted to 92.6% in Poland.
CONCLUSIONS
Maintaining a high percentage of children vaccinated against mumps will provide sustaining decline in cases of mumps in the coming years.
Topics: Age Distribution; Child; Female; Humans; Incidence; Infant; Male; Mass Vaccination; Measles-Mumps-Rubella Vaccine; Mumps; Poland; Rubella; Rural Population; Urban Population
PubMed: 34696560
DOI: 10.32394/pe.75.21 -
Przeglad Epidemiologiczny May 2024Mumps is a contagious viral disease occurring mainly in children, the source of infection being the sick/infected person. Since 2003, vaccination against mumps has been...
INTRODUCTION
Mumps is a contagious viral disease occurring mainly in children, the source of infection being the sick/infected person. Since 2003, vaccination against mumps has been mandatory in Poland, performed according to a two-dose schedule. As part of the Public Health Immunization Program (PSO), the MMR combination vaccine (against measles, mumps and rubella) is used for the entire population of children.
OBJECTIVES
The aim of this study was to evaluate epidemiological indicators of mumps in Poland in 2021 compared to previous years, taking into account the impact of the COVID-19 pandemic.
MATERIAL AND METHODS
The analysis of the epidemiological situation of mumps in Poland in 2021 was based on the interpretation of data from the bulletin , "Infectious diseases and poisonings in Poland in 2021" and , "Immunization in Poland in 2021".
RESULTS
484 cases of mumps were registered in Poland in 2021. The total incidence was 1.3 per 100,000 residents, which was lower than in 2020. The highest incidence of 1.8 per 100,000 residents was registered in Pomorskie Province, and the lowest incidence of 0.7 in Lower Silesia Province. The highest incidence (6.4/100 thousand) was recorded in children aged 0-4 and 5-9. The incidence rate for men (1.4/100,000) was higher than for women (1.1). In 2021, there were 9 patients hospitalized due to mumps, this was more than in 2020.
CONCLUSIONS
The decrease in the number of cases of mumps in 2021 remained related to the ongoing pandemic - the restrictions introduced during the pandemic period led to a decrease in the number of cases not only of COVID-19, but also of other diseases spread by the droplet route, including mumps. The number of registered cases based on the reports of diagnosing physicians may be underestimating the actual number of cases due to the continued difficult access of patients to primary care physicians.
Topics: Humans; Mumps; Poland; Child, Preschool; Infant; Child; Female; Male; Adolescent; Incidence; Adult; Young Adult; COVID-19; Age Distribution; Middle Aged; Infant, Newborn; Measles-Mumps-Rubella Vaccine; Registries; Urban Population; Sex Distribution; Rural Population; SARS-CoV-2
PubMed: 38783656
DOI: 10.32394/pe.77.38 -
Pediatrics Dec 2021Despite a >99% reduction in US mumps cases after the introduction of mumps vaccine in 1967, outbreaks have occurred in schools and other settings involving vaccinated...
BACKGROUND
Despite a >99% reduction in US mumps cases after the introduction of mumps vaccine in 1967, outbreaks have occurred in schools and other settings involving vaccinated children and adolescents since 2006.
METHODS
We analyzed mumps cases reported by US health departments to the National Notifiable Diseases Surveillance System. We present the incidence and vaccination status of pediatric cases (age <18 years) during 2007-2019 and describe demographic, clinical, and vaccination characteristics of pediatric cases reported during the most recent resurgence in 2015-2019.
RESULTS
During 2007-2019, 9172 pediatric cases were reported, accounting for a median of 32% of all cases reported each year (range: 13%-59%). A median of 87% (range: 81%-94%) of pediatric patients each year had previously received ≥1 measles, mumps, and rubella (MMR) vaccine dose. During 2015-2019, of 5461 pediatric cases reported, only 2% of those with known import status (74%) were associated with international travel. One percent of patients had complications and 2% were hospitalized. Among patients aged ≥1 year with known vaccination status (72%), 74% of 1- to 4-year-olds had received ≥1 MMR dose and 86% of 5- to 17-year-olds had received ≥2 MMR doses. Since 2016, pediatric mumps cases have been reported in most US states each year (range: 38-45 states).
CONCLUSIONS
Since 2007, one-third of US reported mumps cases occurred in children and adolescents, the majority of whom were vaccinated. Clinicians should suspect mumps in patients with parotitis or mumps complications, regardless of age, travel history, and vaccination status.
Topics: Adolescent; Age Distribution; Child; Child, Preschool; Disease Outbreaks; Female; Hospitalization; Humans; Immunization, Secondary; Incidence; Infant; Male; Measles-Mumps-Rubella Vaccine; Mumps; Sex Distribution; Time Factors; Travel-Related Illness; United States; Vaccination Coverage
PubMed: 34814181
DOI: 10.1542/peds.2021-051873 -
Epidemiologie, Mikrobiologie,... 2021Mumps is an infectious viral disease transmitted by droplets. It is vaccine preventable and thanks to the start of compulsory vaccination in 1987, there has been a...
Mumps is an infectious viral disease transmitted by droplets. It is vaccine preventable and thanks to the start of compulsory vaccination in 1987, there has been a significant reduction in cases. Nevertheless, over the years, occasional local outbreaks have occurred in the Czech Republic, especially in adolescents, while in Slovakia, since the beginning of vaccination, the situation has been kept under somewhat better control. This may be explained by the differences in the vaccination schedules between the countries and the consequent secondary vaccine failure, the so-called waning of immunity in Czech older children, adolescents, and young adults. The article summarizes current knowledge about mumps and data on its incidence in the Czech Republic and Slovakia.
Topics: Adolescent; Child; Czech Republic; Disease Outbreaks; Humans; Mumps; Slovakia; Vaccination; Young Adult
PubMed: 35073704
DOI: No ID Found -
International Journal of Environmental... May 2022(1) Background: To explore whether meteorological factors have an impact on the prevalence of mumps, and to make a short−term prediction of the case number of mumps in...
(1) Background: To explore whether meteorological factors have an impact on the prevalence of mumps, and to make a short−term prediction of the case number of mumps in Chongqing. (2) Methods: K−means clustering algorithm was used to divide the monthly mumps cases of each year into the high and low case number clusters, and Student t−test was applied for difference analysis. The cross−correlation function (CCF) was used to evaluate the correlation between the meteorological factors and mumps, and an ARIMAX model was constructed by additionally incorporating meteorological factors as exogenous variables in the ARIMA model, and a short−term prediction was conducted for mumps in Chongqing, evaluated by MAE, RMSE. (3) Results: All the meteorological factors were significantly different (p < 0.05), except for the relative humidity between the high and low case number clusters. The CCF and ARIMAX model showed that monthly precipitation, temperature, relative humidity and wind velocity were associated with mumps, and there were significant lag effects. The ARIMAX model could accurately predict mumps in the short term, and the prediction errors (MAE, RMSE) were lower than those of the ARIMA model. (4) Conclusions: Meteorological factors can affect the occurrence of mumps, and the ARIMAX model can effectively predict the incidence trend of mumps in Chongqing, which can provide an early warning for relevant departments.
Topics: China; Humans; Incidence; Meteorological Concepts; Mumps; Wind
PubMed: 35682208
DOI: 10.3390/ijerph19116625