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The Review of Scientific Instruments Mar 2023Surface electromyography (sEMG) is considered an established means for controlling prosthetic devices. sEMG suffers from serious issues such as electrical noise, motion...
Surface electromyography (sEMG) is considered an established means for controlling prosthetic devices. sEMG suffers from serious issues such as electrical noise, motion artifact, complex acquisition circuitry, and high measuring costs because of which other techniques have gained attention. This work presents a new optoelectronic muscle (OM) sensor setup as an alternative to the EMG sensor for precise measurement of muscle activity. The sensor integrates a near-infrared light-emitting diode and phototransistor pair along with the suitable driver circuitry. The sensor measures skin surface displacement (that occurs during muscle contraction) by detecting backscattered infrared light from skeletal muscle tissue. With an appropriate signal processing scheme, the sensor was able to produce a 0-5 V output proportional to the muscular contraction. The developed sensor depicted decent static and dynamic features. In detecting muscle contractions from the forearm muscles of subjects, the sensor showed good similarity with the EMG sensor. In addition, the sensor displayed higher signal-to-noise ratio values and better signal stability than the EMG sensor. Furthermore, the OM sensor setup was utilized to control the rotation of the servomotor using an appropriate control scheme. Hence, the developed sensing system can measure muscle contraction information for controlling assistive devices.
Topics: Humans; Upper Extremity; Electromyography; Muscle, Skeletal; Muscle Contraction; Hand; Isometric Contraction
PubMed: 37012764
DOI: 10.1063/5.0130394 -
European Journal of Applied Physiology Apr 2023Hamstring strain injuries may occur due to differential fatigue and compromised mechanical properties among the hamstring muscles. We examined (1) the effect of fatigue...
PURPOSE
Hamstring strain injuries may occur due to differential fatigue and compromised mechanical properties among the hamstring muscles. We examined (1) the effect of fatigue on hamstrings active muscle stiffness, and (2) whether contraction type affects active muscle stiffness changes during a submaximal fatiguing task.
METHODS
Nine healthy males completed 99 submaximal knee flexions in isometric (ISO), concentric (CON), and eccentric (ECC) conditions. We measured the knee flexor maximal voluntary torque (MVT) (pre/post), shear wave velocity (SWV) during contraction and transverse relaxation times (T2) (pre/post) in biceps femoris long head (BFlh), semitendinosus (ST), and semimembranosus (SM) muscles.
RESULTS
MVT decreased substantially after all conditions (- 18.4 to - 33.6%). The average relative torque sustained during the task was lower in CON than ISO and ECC, but absolute torque was similar. SWV interindividual responses were highly variable across muscles and contraction types. On average, BFlh SWV tended to increase in ISO (0.4 m/s, 4.5%, p = 0.064) but decreased in ECC condition (- 0.8 m/s, - 7.7%, p < 0.01). ST SWV decreased in CON (- 1.1 m/s, - 9.0%, p < 0.01), while it remained unchanged in ISO and ECC. SM SWV decreased in CON (- 0.8 m/s, - 8.1%, p < 0.01), but it was unaffected in ISO and variable in ECC.
CONCLUSION
Fatigue has a differential effect on the mechanical properties of the constituent hamstring muscles, as measured with shear wave elastography, depending upon contraction type. We found preliminary evidence that BFlh is more fatigued than ST or SM during eccentric contractions, which may explain its susceptibility to strain injuries.
Topics: Male; Humans; Hamstring Muscles; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Isometric Contraction; Torque; Electromyography
PubMed: 36494585
DOI: 10.1007/s00421-022-05104-0 -
Biomedical Engineering Online Jul 2022Advances in sports medicine, rehabilitation applications and diagnostics of neuromuscular disorders are based on the analysis of skeletal muscle contractions. Recently,...
BACKGROUND
Advances in sports medicine, rehabilitation applications and diagnostics of neuromuscular disorders are based on the analysis of skeletal muscle contractions. Recently, medical imaging techniques have transformed the study of muscle contractions, by allowing identification of individual motor units' activity, within the whole studied muscle. However, appropriate image-based simulation models, which would assist the continued development of these new imaging methods are missing. This is mainly due to a lack of models that describe the complex interaction between tissues within a muscle and its surroundings, e.g., muscle fibres, fascia, vasculature, bone, skin, and subcutaneous fat. Herein, we propose a new approach to overcome this limitation.
METHODS
In this work, we propose to use deep learning to model the authentic intra-muscular skeletal muscle contraction pattern using domain-to-domain translation between in silico (simulated) and in vivo (experimental) image sequences of skeletal muscle contraction dynamics. For this purpose, the 3D cycle generative adversarial network (cycleGAN) models were evaluated on several hyperparameter settings and modifications. The results show that there were large differences between the spatial features of in silico and in vivo data, and that a model could be trained to generate authentic spatio-temporal features similar to those obtained from in vivo experimental data. In addition, we used difference maps between input and output of the trained model generator to study the translated characteristics of in vivo data.
RESULTS
This work provides a model to generate authentic intra-muscular skeletal muscle contraction dynamics that could be used to gain further and much needed physiological and pathological insights and assess and overcome limitations within the newly developed research field of neuromuscular imaging.
Topics: Computer Simulation; Image Processing, Computer-Assisted; Muscle Contraction
PubMed: 35804415
DOI: 10.1186/s12938-022-01016-4 -
Computer Methods in Biomechanics and... Jun 2023Pelvic floor disorders affect 24% of US women, and elevated intra-abdominal pressure may cause pelvic injury through musculoskeletal strain. Activity restrictions meant...
Pelvic floor disorders affect 24% of US women, and elevated intra-abdominal pressure may cause pelvic injury through musculoskeletal strain. Activity restrictions meant to reduce pelvic strain after traumatic events, such as childbirth, have shown little benefit to patients. Reported high variability in abdominal pressure suggests that technique plays a substantial role in pressure generation. Understanding these techniques could inform evidence-based recommendations for protective pelvic care. We hypothesized use of a motion-capture methodology could identify four major contributors to elevated pressure: gravity, acceleration, abdominal muscle contraction, and respiration. Twelve women completed nineteen activities while instrumented for whole body motion capture, abdominal pressure, hip acceleration, and respiration volume. Correlation and partial least squares regression were utilized to determine primary technique factors that increase abdominal pressure. The partial least squares model identified two principal components that explained 59.63% of relative intra-abdominal pressure variability. The first component was primarily loaded by hip acceleration and relative respiration volume, and the second component was primarily loaded by flexion moments of the abdomen and thorax. While reducing abdominal muscle use has been a primary strategy in protective pelvic floor care, the influence of hip acceleration and breathing patterns should be considered with similar importance in future work.
Topics: Humans; Female; Pressure; Pelvic Floor; Abdomen; Muscle Contraction; Respiration
PubMed: 35837994
DOI: 10.1080/10255842.2022.2100220 -
European Journal of Applied Physiology Feb 2019The present study aimed to identify whether or not an increase in ciliary-muscle contraction force, when the eye-lens is adjusted for viewing at a near distance, results...
The present study aimed to identify whether or not an increase in ciliary-muscle contraction force, when the eye-lens is adjusted for viewing at a near distance, results in an increase in trapezius muscle activity, while performing a natural work task. Twelve participants, ranging in age from 21 to 32 years, performed a computer-mouse work task during free gaze conditions. A moving visual target was tracked with a computer mouse on a screen placed at two different distances from the eyes, 25 cm and 50 cm. Tracking performance, eye accommodation, and bilateral trapezius muscle activity were measured continuously. Ciliary-muscle contraction force was computed according to a formula which takes into account the age-dependent, non-linear relationship between the contraction force of the ciliary muscle and the produced level of eye accommodation. Generalized estimating equations analyses were performed. On the dominant hand side and for the nearest screen distance, there was a significant effect of ciliary-muscle contraction force on the trapezius muscle activity (p < 0.001). No other effects were significant (p > 0.05). The results support the hypothesis that high visual demands, during computer mouse work, increase ciliary muscle contraction force and contribute to a raise of the sustained level of trapezius muscle activity. The current study specifically clarifies the validity of the relationship between ciliary-muscle contraction force and trapezius muscle activity and demonstrates that this relationship is not due to a general personality trait. We conclude that a high level of ciliary muscle contraction force can contribute to a development of musculoskeletal complaints in the neck-shoulder area.
Topics: Accommodation, Ocular; Adult; Computers; Female; Humans; Male; Movement; Muscle Contraction; Superficial Back Muscles; Young Adult
PubMed: 30430279
DOI: 10.1007/s00421-018-4031-8 -
American Journal of Physiology.... May 2024The force drop after transcranial magnetic stimulation (TMS) delivered to the motor cortex during voluntary muscle contractions could inform about muscle relaxation...
The force drop after transcranial magnetic stimulation (TMS) delivered to the motor cortex during voluntary muscle contractions could inform about muscle relaxation properties. Because of the physiological relation between skeletal muscle fiber-type distribution and size and muscle relaxation, TMS could be a noninvasive index of muscle relaxation in humans. By combining a noninvasive technique to record muscle relaxation in vivo (TMS) with the gold standard technique for muscle tissue sampling (muscle biopsy), we investigated the relation between TMS-induced muscle relaxation in unfatigued and fatigued states, and muscle fiber-type distribution and size. Sixteen participants (7F/9M) volunteered to participate. Maximal knee-extensor voluntary isometric contractions were performed with TMS before and after a 2-min sustained maximal voluntary isometric contraction. Vastus lateralis muscle tissue was obtained separately from the participants' dominant limb. Fiber type I distribution and relative cross-sectional area of fiber type I correlated with TMS-induced muscle relaxation at baseline ( = 0.67, adjusted = 0.01; = 0.74, adjusted = 0.004, respectively) and normalized TMS-induced muscle relaxation as a percentage of baseline ( = 0.50, adjusted = 0.049; = 0.56, adjusted = 0.031, respectively). The variance in the normalized peak relaxation rate at baseline (59.8%, < 0.001) and in the fatigue resistance (23.0%, = 0.035) were explained by the relative cross-sectional area of fiber type I to total fiber area. Fiber type I proportional area influences TMS-induced muscle relaxation, suggesting TMS as an alternative method to noninvasively inform about skeletal muscle relaxation properties. Transcranial magnetic stimulation (TMS)-induced muscle relaxation reflects intrinsic muscle contractile properties by interrupting the drive from the central nervous system during voluntary muscle contractions. We showed that fiber type I proportional area influences the TMS-induced muscle relaxation, suggesting that TMS could be used for the noninvasive estimation of muscle relaxation in unfatigued and fatigued human muscles when the feasibility of more direct method to study relaxation properties (i.e., muscle biopsy) is restricted.
Topics: Humans; Transcranial Magnetic Stimulation; Electric Stimulation; Muscle, Skeletal; Muscle Relaxation; Muscle Fatigue; Muscle Contraction; Isometric Contraction; Muscle Fibers, Skeletal; Electromyography
PubMed: 38525536
DOI: 10.1152/ajpregu.00174.2023 -
The Journal of Experimental Biology Jun 2017Performance of muscle-powered movements depends on temperature through its effects on muscle contractile properties. stimulation of Cuban treefrog () plantaris muscles...
Performance of muscle-powered movements depends on temperature through its effects on muscle contractile properties. stimulation of Cuban treefrog () plantaris muscles reveals that interactions between force and temperature affect the mechanical work of muscle. At low temperatures (9-17°C), muscle work depends on temperature when shortening at any force, and temperature effects are greater at higher forces. At warmer temperatures (13-21°C), muscle work depends on temperature when shortening with intermediate and high forces (≥30% peak isometric tetanic force). Shortening velocity is most strongly affected by temperature at low temperatures and high forces. Power is also most strongly affected at low temperature intervals, but this effect is minimized at intermediate forces. Effects of temperature on muscle force explain these interactions; force production decreases at lower temperatures, increasing the challenge of moving a constant force relative to the muscle's capacity. These results suggest that animal performance that requires muscles to do work with low forces relative to a muscle's maximum force production will be robust to temperature changes, and this effect should be true whether muscle acts directly or through elastic-recoil mechanisms and whether force is prescribed (i.e. internal) or variable (i.e. external). Conversely, performance requiring muscles to shorten with relatively large forces is expected to be more sensitive to temperature changes.
Topics: Animals; Anura; Biomechanical Phenomena; Electric Stimulation; Isotonic Contraction; Muscle Contraction; Muscle, Skeletal; Temperature
PubMed: 28314747
DOI: 10.1242/jeb.153114 -
Journal of Neural Engineering Sep 2022The study of human neuromechanical control at the motor unit (MU) level has predominantly focussed on electrical activity and force generation, whilst the link between...
The study of human neuromechanical control at the motor unit (MU) level has predominantly focussed on electrical activity and force generation, whilst the link between these, i.e. the muscle deformation, has not been widely studied. To address this gap, we analysed the kinematics of muscle units in natural contractions.We combined high-density surface electromyography (HDsEMG) and ultrafast ultrasound (US) recordings, at 1000 frames per second, from the tibialis anterior muscle to measure the motion of the muscular tissue caused by individual MU contractions. The MU discharge times were identified online by decomposition of the HDsEMG and provided as biofeedback to 12 subjects who were instructed to keep the MU active at the minimum discharge rate (9.8 ± 4.7 pulses per second; force less than 10% of the maximum). The series of discharge times were used to identify the velocity maps associated with 51 single muscle unit movements with high spatio-temporal precision, by a novel processing method on the concurrently recorded US images. From the individual MU velocity maps, we estimated the region of movement, the duration of the motion, the contraction time, and the excitation-contraction (E-C) coupling delay.Individual muscle unit motions could be reliably identified from the velocity maps in 10 out of 12 subjects. The duration of the motion, total contraction time, and E-C coupling were 17.9±5.3 ms, 56.6±8.4 ms, and 3.8±3.0 ms (= 390 across ten participants). The experimental measures also provided the first evidence of muscle unit twisting during voluntary contractions and MU territories with distinct split regions.The proposed method allows for the study of kinematics of individual MU twitches during natural contractions. The described measurements and characterisations open new avenues for the study of neuromechanics in healthy and pathological conditions.
Topics: Biomechanical Phenomena; Electromyography; Humans; Isometric Contraction; Motor Neurons; Muscle Contraction; Muscle, Skeletal
PubMed: 36001952
DOI: 10.1088/1741-2552/ac8c6c -
Journal of the Mechanical Behavior of... Oct 2022One of the skeletal muscle's exceptional properties is its high damage tolerance in terms of its high toughness, which allows the muscle to withstand cracks of...
One of the skeletal muscle's exceptional properties is its high damage tolerance in terms of its high toughness, which allows the muscle to withstand cracks of millimeter length while maintaining most of its strength (Taylor et al., 2012). In skeletal muscles, damage occurs on different hierarchical levels of the microstructure. We analyze the damage behavior on hierarchy levels 3 (muscle fiber) and 4 (fascicle) on which the most common serious muscle injuries occur. Our model captures damage initiation and rupture of activated muscle fibers resulting from eccentric contractions. We consider the interaction between muscle fibers and endomysium and investigate the influence of the components titin and endomysium on the mechanical behavior in pre-damaged fascicles. Endomysium generally transmits contractile forces. Our results show that high strains in pre-damaged fiber regions are not transferred by the endomysium and, thus, adjacent undamaged fibers are well protected. Moreover, the results show titin's extraordinary stabilization properties of pre-damaged muscle fibers, so that macroscopic strains of fascicles are hardly reduced in case of strongly pre-damaged fibers and intact titin.
Topics: Computer Simulation; Connectin; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal
PubMed: 35952441
DOI: 10.1016/j.jmbbm.2022.105386 -
Acta Physiologica (Oxford, England) May 2023Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized, among the others, by muscle weakness. PD patients reach lower values of peak torque...
AIM
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized, among the others, by muscle weakness. PD patients reach lower values of peak torque during maximal voluntary contractions but also slower rates of torque development (RTD) during explosive contractions. The aim of this study was to better understand how an impairment in structural/mechanical (peripheral) factors could explain the difficulty of PD patients to raise torque rapidly.
METHODS
Participants (PD patients and healthy matched controls) performed maximum voluntary explosive fixed-end contraction of the knee extensor muscles during which dynamic muscle shape changes (in muscle thickness, pennation angle, and belly gearing: the ratio between muscle belly velocity and fascicle velocity), muscle-tendon unit (MTU) stiffness and EMG activity of the vastus lateralis (VL) were investigated. Both the affected (PDA) and less affected limb (PDNA) were investigated in patients.
RESULTS
Control participants reached higher values of peak torque and showed a better capacity to express force rapidly compared to patients (PDA and PDNA). EMG activity was observed to differ between patients (PDA) and controls, but not between controls and PDNA. This suggests a specific neural/nervous effect on the most affected side. On the contrary, MTU stiffness and dynamic muscle shape changes were found to differ between controls and patients, but not between PDA and PDNA. Both sides are thus similarly affected by the pathology.
CONCLUSION
The higher MTU stiffness in PD patients is likely responsible for the impaired muscle capability to change in shape which, in turn, negatively affects the torque rise.
Topics: Humans; Parkinson Disease; Muscle, Skeletal; Tendons; Quadriceps Muscle; Knee Joint; Torque; Muscle Contraction; Isometric Contraction; Electromyography
PubMed: 36876976
DOI: 10.1111/apha.13957