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Thoracic Surgery Clinics May 2024Diaphragm tumors are very rare, with secondary tumors being more common than primary tumors. The most common benign primary tumors include lipomas and cysts, and... (Review)
Review
Diaphragm tumors are very rare, with secondary tumors being more common than primary tumors. The most common benign primary tumors include lipomas and cysts, and malignant primary tumors include rhabdomyosarcoma and leiomyosarcoma. Endometriosis is the most common benign secondary tumor, followed by malignant tumors with localized spread of disease. In addition, widely metastatic disease has been described. Benign lipomas and cysts can be managed conservatively, but more complex or concerning disease typically requires resection. The diaphragm can often be repaired primarily, though any large defect or tension would indicate the need for mesh or an autologous reconstruction.
Topics: Humans; Diaphragm; Muscle Neoplasms
PubMed: 38705667
DOI: 10.1016/j.thorsurg.2024.01.009 -
Seminars in Roentgenology Oct 2017
Topics: Bone Neoplasms; Diagnostic Imaging; Humans; Muscle Neoplasms; Musculoskeletal System
PubMed: 28965539
DOI: 10.1053/j.ro.2017.09.001 -
The Journal of the American Academy of... Jul 2020Melanoma is an aggressive form of skin cancer associated with significant morbidity and mortality. Although commonly seen in dermatologist clinics, orthopaedic surgeons... (Review)
Review
Melanoma is an aggressive form of skin cancer associated with significant morbidity and mortality. Although commonly seen in dermatologist clinics, orthopaedic surgeons must be aware of these lesions in various ways. The five common musculoskeletal manifestations of melanoma will be discussed as well as the epidemiology, pathogenesis, diagnosis, staging, treatment, and prognosis of melanoma. With an index of suspicion and awareness of melanoma, a thorough history and detailed physical examination are critical in establishing a diagnosis. An adequately performed biopsy will confirm the diagnosis and assist in determining prognosis. As ambassadors of health for the musculoskeletal system, orthopaedic surgeons may be the first practitioners to encounter a pigmented skin lesion. Acral pigmented lesions should prompt a concern for melanoma with appropriate subsequent steps for management to follow. Finally, it is important for every orthopaedic surgeon to consider disseminated melanoma in the differential diagnosis of a skeletal metastasis, a deep soft-tissue mass, or lymphadenopathy in a patient with a previous history of a melanotic lesion.
Topics: Biopsy; Bone Neoplasms; Diagnosis, Differential; Humans; Melanoma; Muscle Neoplasms; Orthopedic Surgeons; Orthopedics; Physical Examination; Prognosis; Skin; Skin Neoplasms
PubMed: 32097135
DOI: 10.5435/JAAOS-D-18-00757 -
Abdominal Radiology (New York) Nov 2017Urothelial bladder cancer is a common malignancy requiring a multidisciplinary approach to treatment. Significant recent advances have been made in terms of the genetic... (Review)
Review
Urothelial bladder cancer is a common malignancy requiring a multidisciplinary approach to treatment. Significant recent advances have been made in terms of the genetic and molecular characterization of bladder cancer subtypes, and novel treatment approaches are being investigated and approved. Given the important role of imaging in the diagnosis, staging, and follow-up of this disease, it is necessary for radiologists to remain up-to-date in terms of nomenclature and standards of care. In this review, recent developments in bladder cancer characterization and treatment will be discussed, with reference to the contributions of imaging in non-muscle-invasive, muscle-invasive, and metastatic settings.
Topics: Humans; Muscle Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Urinary Bladder Neoplasms
PubMed: 28580540
DOI: 10.1007/s00261-017-1195-3 -
RoFo : Fortschritte Auf Dem Gebiete Der... Nov 2020
Topics: Abdominal Neoplasms; Contrast Media; Diagnosis, Differential; Humans; Liposarcoma; Liposarcoma, Myxoid; Magnetic Resonance Imaging; Muscle Neoplasms; Neoplasm Grading; Pelvic Neoplasms; Retroperitoneal Neoplasms; Soft Tissue Neoplasms; Tomography, X-Ray Computed
PubMed: 32106323
DOI: 10.1055/a-1108-1961 -
Clinical Orthopaedics and Related... Apr 2019
Topics: Bone Neoplasms; Congresses as Topic; Humans; Muscle Neoplasms; Treatment Outcome
PubMed: 30811356
DOI: 10.1097/CORR.0000000000000653 -
RoFo : Fortschritte Auf Dem Gebiete Der... May 2018
Topics: Calcinosis; Diagnosis, Differential; Hematoma; Humans; Muscle Neoplasms; Muscle, Skeletal; Necrosis; Tomography, X-Ray Computed
PubMed: 29672789
DOI: 10.1055/s-0044-100729 -
The Journal of Bone and Joint Surgery.... Dec 2019
Topics: Bone Neoplasms; Humans; Muscle Neoplasms; Orthopedic Procedures
PubMed: 31609895
DOI: 10.2106/JBJS.19.00961 -
Journal of the American Veterinary... Oct 2018
Topics: Animals; Diagnosis, Differential; Dog Diseases; Dogs; Hemangiosarcoma; Hindlimb; Lameness, Animal; Male; Muscle Neoplasms; Necrosis
PubMed: 30211648
DOI: 10.2460/javma.253.7.861 -
PET Clinics Oct 2017Skeletal and soft tissue sarcomas need early and accurate diagnosis, staging, and treatment for optimal outcome. F-FDG PET/computed tomography (CT) is indicated in... (Review)
Review
Skeletal and soft tissue sarcomas need early and accurate diagnosis, staging, and treatment for optimal outcome. F-FDG PET/computed tomography (CT) is indicated in staging of patients with high-grade sarcomas and acts as a surrogate marker of histopathologic grade, guiding biopsy to most aggressive portion of the tumor. Pretherapy and posttherapy F-FDG PET/CT metabolic parameters are reliable indicators of survival in patients with sarcoma with an important role in posttreatment response assessment, enabling the treatment plan to be modified in nonresponders. F-FDG PET/CT is particularly useful in the evaluation of molecular targeted therapies, which induce metabolic change before structural change.
Topics: Bone Neoplasms; Fluorodeoxyglucose F18; Humans; Muscle Neoplasms; Positron Emission Tomography Computed Tomography; Precision Medicine; Radiopharmaceuticals; Sarcoma
PubMed: 28867117
DOI: 10.1016/j.cpet.2017.05.005