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Surgical Pathology Clinics Mar 2017This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis,... (Review)
Review
This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and diagnostic pitfalls are addressed for inflammatory cysts (periapical cyst, mandibular infected buccal cyst/paradental cyst), developmental cysts (dentigerous, lateral periodontal, glandular odontogenic, orthokeratinized odontogenic cyst), benign tumors (keratocystic odontogenic tumor, ameloblastoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma and fibroodontoma, odontoma, squamous odontogenic tumor, calcifying cystic odontogenic tumor, primordial odontogenic tumor, central odontogenic fibroma, and odontogenic myxomas), and malignant tumors (clear cell odontogenic carcinoma, ameloblastic carcinoma, ameloblastic fibrosarcoma).
Topics: Dentigerous Cyst; Diagnosis, Differential; Humans; Odontogenic Cysts; Odontogenic Tumors; Periodontal Cyst; Prognosis; Radicular Cyst; Radiography, Dental
PubMed: 28153133
DOI: 10.1016/j.path.2016.10.006 -
Head and Neck Pathology Mar 2021This article reviews odontogenic and developmental oral lesions encountered in the gnathic region of pediatric patients. The process of odontogenesis is discussed as it... (Review)
Review
This article reviews odontogenic and developmental oral lesions encountered in the gnathic region of pediatric patients. The process of odontogenesis is discussed as it is essential to understanding the pathogenesis of odontogenic tumors. The clinical presentation, microscopic features, and prognosis are addressed for odontogenic lesions in the neonate (dental lamina cysts/gingival cysts of the newborn, congenital (granular cell) epulis of the newborn, melanotic neuroectodermal tumor, choristoma/heterotopia, cysts of foregut origin), lesions associated with unerupted/erupting teeth (hyperplastic dental follicle, eruption cyst, dentigerous cyst, odontogenic keratocyst/keratocystic odonogenic tumor, buccal bifurcation cyst/inflammatory collateral cyst) and pediatric odontogenic hamartomas and tumors (odontoma, ameloblastic fibroma, ameloblastoma, adenomatoid odontogenic tumor, primordial odontogenic tumor). Pediatric odontogenic and developmental oral lesions range from common to rare, but familiarity with these entities is essential due to the varying management implications of these diagnoses.
Topics: Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Jaw Diseases; Male; Odontogenesis; Tooth Abnormalities
PubMed: 33723756
DOI: 10.1007/s12105-020-01284-3 -
Children (Basel, Switzerland) Oct 2022Compound odontoma is a malformation typical of young adults below the age of 20, with a slight preference for the male gender and the anterior region of the maxilla.... (Review)
Review
Compound odontoma is a malformation typical of young adults below the age of 20, with a slight preference for the male gender and the anterior region of the maxilla. Clinically asymptomatic, it can be detected during a radiological investigation in connection with the persistence of deciduous dental elements and the impaction of definitive ones. The treatment of choice is excisional surgery and recurrence is a rare event. The need for orthodontic therapy for impacted elements is usually not necessary because in most cases, odontomas are small, circumscribed lesions the size of a permanent tooth. In this article, the diagnostic and therapeutic surgical excision procedure is presented in three patients at developmental age with large compound odontomas associated with at least one retained canine, and in two of the cases, with serious transmigration to the impacted tooth elements.
PubMed: 36291445
DOI: 10.3390/children9101509 -
Pediatric and Developmental Pathology :... 2023Odontogenic tumors are rare tumors of the jaws that arise from remnants of the tooth forming apparatus. Some odontogenic tumors demonstrate strong predilection for... (Review)
Review
Odontogenic tumors are rare tumors of the jaws that arise from remnants of the tooth forming apparatus. Some odontogenic tumors demonstrate strong predilection for pediatric patients including the unicystic ameloblastoma, adenomatoid odontogenic tumor, ameloblastic fibroma, ameloblastic fibro-odontoma, odontoma, and primordial odontogenic tumor. In this review, we discuss the clinical, radiographic, histopathologic, and molecular characteristics of select odontogenic tumors that demonstrate pediatric predilection and review management.
Topics: Humans; Child; Odontogenic Tumors; Ameloblastoma; Odontoma
PubMed: 38032744
DOI: 10.1177/10935266231200115 -
Journal of Dentistry For Children... Sep 2018The ameloblastic fibro-odontoma (AFO) is a rare, mixed odontogenic tumor exhibiting the histological characters of the ameloblastic fibroma and complex odontoma. It is...
The ameloblastic fibro-odontoma (AFO) is a rare, mixed odontogenic tumor exhibiting the histological characters of the ameloblastic fibroma and complex odontoma. It is comprised of proliferating ectodermal and mesenchymal components of odontogenic tissue as well as enamel and dentin. AFO normally presents as an asymptomatic swelling of the posterior maxilla or mandible and is usually associated with developing teeth, occurring predominantly in children and adolescents. Such lesions are generally found upon radiographic examination of patients whose tooth eruption is delayed. This lesion often includes an unerupted permanent tooth, and extraction of this tooth is a common treatment. The purpose of this report is to describe an AFO in the posterior mandible of a nine-year-old girl for whom enucleation was performed under general anesthesia without extracting the displaced permanent mandibular left second molar. Two years later, the tooth erupted into occlusion without tumor recurrence.
Topics: Anesthesia, General; Child; Cone-Beam Computed Tomography; Dental Enamel; Dentin; Epithelial Cells; Female; Humans; Mandible; Mandibular Neoplasms; Molar; Odontoma; Patient Care Planning; Radiography, Panoramic; Tooth Eruption; United Kingdom
PubMed: 30869592
DOI: No ID Found -
European Journal of Paediatric Dentistry Sep 2020Odontomas are hamartomatous developmental malformations of the dental tissues. Usually asymptomatic, their presence is often revealed on routine radiographs. The study... (Review)
Review
BACKGROUND
Odontomas are hamartomatous developmental malformations of the dental tissues. Usually asymptomatic, their presence is often revealed on routine radiographs. The study aimed to establish the efficacy of this conventional approach in treating odontomas, analysing clinical outcome, follow-up, and histomorphological profile.
CASE REPORT
A case is presented with a review of the international literature. The patient, aged 8 years, had a complex odontoma localised on the front upper jaw. She was treated following the conventional surgical procedure. Post-operative course and healing were uneventful. Orthodontic treatment was necessary to realign the teeth. At the 12-month follow-up there was no recurrence or failure. Healing was excellent.
CONCLUSION
Variations in normal tooth eruption are a common finding, but significant deviations from established norms should alert the clinician to further investigate the patient's health and development.
Topics: Child; Female; Humans; Maxilla; Neoplasm Recurrence, Local; Odontoma; Tooth Eruption; Tooth, Impacted
PubMed: 32893652
DOI: 10.23804/ejpd.2020.21.03.08 -
Fetal and Pediatric Pathology Apr 2023Ameloblastic fibro-odontoma (AFO) is a benign odontogentic tumor without an aggressive behavior, unlike the similar ameloblastic fibroma. A 9-year-old boy, with tooth...
Ameloblastic fibro-odontoma (AFO) is a benign odontogentic tumor without an aggressive behavior, unlike the similar ameloblastic fibroma. A 9-year-old boy, with tooth eruption failure, underwent enucleation and curettage of a well-defined variable radiolucent and radio-opaque right mandible lesion. There was odontogenic epithelium with peripheral palisading in a loose myxoid stroma as well as a disorganized component of dentin, enamel, and cementum, features of an AFO. AFO is an odontogenic mixed tumor of epithelium and mesenchyme.
Topics: Male; Humans; Child; Odontoma; Mandibular Neoplasms; Epithelium; Head; Connective Tissue
PubMed: 35748698
DOI: 10.1080/15513815.2022.2088910 -
Ear, Nose, & Throat Journal Sep 2021
Topics: Adolescent; Adult; Child; Female; Humans; Male; Mandibular Neoplasms; Medical Illustration; Odontoma; Young Adult
PubMed: 31760790
DOI: 10.1177/0145561319890175 -
Oral and Maxillofacial Surgery Clinics... Feb 2016Pediatric odontogenic tumors are rare, and are often associated with impacted teeth. Although they can develop anywhere in the jaws, odontogenic tumors mainly occur in... (Review)
Review
Pediatric odontogenic tumors are rare, and are often associated with impacted teeth. Although they can develop anywhere in the jaws, odontogenic tumors mainly occur in the posterior mandible. This article discusses the diagnosis and treatment of the most common pediatric odontogenic tumors, such as ameloblastoma, keratocystic odontogenic tumor, odontoma, and cementoblastoma.
Topics: Biopsy; Child; Diagnostic Imaging; Humans; Odontogenic Tumors
PubMed: 26614700
DOI: 10.1016/j.coms.2015.08.003 -
Dental Clinics of North America Jan 2020Odontogenic tumors are a group of neoplastic growths that originate from the tissues responsible for tooth formation and the periodontal apparatus of the jaw.... (Review)
Review
Odontogenic tumors are a group of neoplastic growths that originate from the tissues responsible for tooth formation and the periodontal apparatus of the jaw. Odontogenic tumors usually present as radiolucent defect, which makes diagnosis somewhat confusing while differentiating them from cysts. Although cystic lesions are surrounded by sclerotic borders, few odontogenic tumors share similar features. This article reviews clinical concepts of several odontogenic tumors that occur in the proximity or in association with teeth and not merely focusing on relatively common conditions.
Topics: Humans; Odontogenic Cysts; Odontogenic Tumors; Tooth
PubMed: 31735223
DOI: 10.1016/j.cden.2019.08.008