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The Veterinary Record Apr 2020
Review
Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Fatty Acids, Essential; Foot Dermatoses; Hoof and Claw; Treatment Outcome
PubMed: 32299980
DOI: 10.1136/vr.m967 -
Italian Journal of Dermatology and... Dec 2021
Topics: Casts, Surgical; Humans; Nail Diseases; Nails, Malformed
PubMed: 31302979
DOI: 10.23736/S2784-8671.19.06365-X -
Skin Appendage Disorders Sep 2015Cutaneous T-cell lymphoma (CTCL) encompasses a broad range of lymphoproliferative diseases affecting the skin and can be clinically misleading due to its variable... (Review)
Review
BACKGROUND
Cutaneous T-cell lymphoma (CTCL) encompasses a broad range of lymphoproliferative diseases affecting the skin and can be clinically misleading due to its variable presentation. Nail alterations commonly appear in advanced-stage mycosis fungoides and true Sézary syndrome; however, they may be present in any stage of the disease. Although proper recognition of nail involvement in CTCL has both clinical and therapeutic value, specific nail findings have been infrequently described in the current literature.
OBSERVATIONS
We describe 4 patients with CTCL who presented with clinically significant nail alterations. The most common findings were nail discoloration, thickening, crumbling, onycholysis, and onychomadesis. Other notable findings included splinter hemorrhages, subungual hyperkeratosis, and anonychia.
CONCLUSIONS AND MESSAGE
The described cases illustrate many of the documented nail findings associated with CTCL and emphasize the variable nature of nail manifestations. The presence of specific nail alterations should increase the clinical suspicion of CTCL - especially in patients with concomitant systemic and/or cutaneous manifestations - and early biopsy specimens should be taken for diagnosis. Nail alterations should also be accurately described and monitored in all patients with biopsy-confirmed CTCL to help identify treatment response and detect disease recurrence.
PubMed: 27170938
DOI: 10.1159/000433474 -
JAMA Dermatology Sep 2018
Topics: Adult; Animals; Beauty Culture; Cosmetic Techniques; Female; Fishes; Humans; Nail Diseases; Nails, Malformed
PubMed: 29971352
DOI: 10.1001/jamadermatol.2018.1827 -
Journal of the American Academy of... Feb 2024
Topics: Humans; T-Lymphocytes; Protein C; Antibodies, Bispecific; Multiple Myeloma; Receptors, G-Protein-Coupled
PubMed: 37742842
DOI: 10.1016/j.jaad.2023.08.094 -
The Pediatric Infectious Disease Journal Apr 2015Hand-foot-and-mouth disease (HFMD) is a common self-limited viral illness seen in the United States and around the world. Its classic features are easily recognizable;...
Hand-foot-and-mouth disease (HFMD) is a common self-limited viral illness seen in the United States and around the world. Its classic features are easily recognizable; however, nail changes are not well known or characterized. This case demonstrates onychomadesis and Beau lines in a child following clinical diagnosis of hand-foot-and-mouth disease. In this setting, nail dystrophies should be reassuring to pediatricians and families.
Topics: Child, Preschool; Hand, Foot and Mouth Disease; Humans; Male; Nails; United States
PubMed: 25764101
DOI: 10.1097/INF.0000000000000574 -
Clinical and Experimental Dermatology Dec 2021Cutaneous findings are well known in atopic dermatitis (AD), but nail changes have not received as much attention.
BACKGROUND
Cutaneous findings are well known in atopic dermatitis (AD), but nail changes have not received as much attention.
AIM
To determine the clinical and disease-related capillaroscopic findings of nail findings in paediatric patients with AD.
METHODS
In total, 100 participants aged 2-16 years were sourced from the dermatology outpatient clinic: 50 of these had been diagnosed with AD according to the Hanifin-Rajka criteria, and the others were 50 healthy controls (HCs) without AD. The AD severity score (SCORing Atopic Dermatitis; SCORAD) was calculated for all patients with AD. A digital epiluminescence device was used for nailfold capillaroscopy.
RESULTS
The nail findings detected in patients with AD were pitting, punctate leuconychia, trachyonychia, onycholysis and onychomadesis. Pitting was significantly (P < 0.01) more frequent in the patient group (26%) than in the HC group (6%). Similarly, the patient group had significantly higher rates for capillary density decrease (P < 0.01), capillary array irregularity (P < 0.001), capillary dilatation increase (P < 0.001), tortuosity (P = 0.04), ramification increase (P = 0.02), bush-like appearance (P = 0.02) and avascular areas (P < 0.01). Significant correlations were determined between pitting and trachyonychia (P < 0.05, r = 0.21), capillary density decrease (P < 0.05, r = 0.25), avascular areas (P < 0.001; r = 0.29) and SCORAD (P < 0.05, r = 0.35).
CONCLUSION
The nailfold capillaroscopic images of children with AD were similar to those of scleroderma spectrum disorder. Thus, we believe it would be beneficial to support detailed clinical examination of patients with a capillaroscopic examination.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dermatitis, Atopic; Female; Humans; Male; Microcirculation; Microscopic Angioscopy; Nails; Vasodilation
PubMed: 34089190
DOI: 10.1111/ced.14783 -
Proceedings (Baylor University. Medical... Jan 2021Kawasaki disease is a vasculitis of medium-sized vessels and the most common cause of acquired heart defects in the United States. Although its etiology is unclear, an...
Kawasaki disease is a vasculitis of medium-sized vessels and the most common cause of acquired heart defects in the United States. Although its etiology is unclear, an infectious trigger has been theorized, which has been highlighted by the recent pandemic. We present a case of a 17-month-old-girl with concurrent Kawasaki disease and non-SARS-CoV2 coronavirus infection and a sequela of onychomadesis.
PubMed: 33953481
DOI: 10.1080/08998280.2020.1866930 -
Indian Journal of Dermatology,... May 2024
PubMed: 38841936
DOI: 10.25259/IJDVL_1269_2023 -
Cutis May 2016
Topics: Child, Preschool; Diagnosis, Differential; Female; Hand, Foot and Mouth Disease; Humans; Nails, Malformed; Onychomycosis
PubMed: 27274554
DOI: No ID Found