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Laryngo- Rhino- Otologie May 2024Diagnosis and therapy of orbital diseases is an interdisciplinary challenge, in which i.e. otorhinolaryngologists, ophthalmologists, radiologists, radiation therapists,... (Review)
Review
Diagnosis and therapy of orbital diseases is an interdisciplinary challenge, in which i.e. otorhinolaryngologists, ophthalmologists, radiologists, radiation therapists, maxillo-facial surgeons, endocrinologists, and pediatricians are involved. This review article describes frequent diseases which both, otolaryngologists and ophthalmologists are concerned with in interdisciplinary settings. In particular the inflammatory diseases of the orbit including orbital complications, autoimmunological diseases of the orbit including GraveĀ“s orbitopathy, and primary and secondary tumors of the orbit are discussed. Beside describing the clinical characteristics and diagnostic steps the article focusses on the interdisciplinary therapy. The review is completed by the presentation of most important surgical approaches to the orbit, their indications and possible complications. The authors tried to highlight the relevant facts despite the shortness of the text.
Topics: Humans; Orbital Diseases; Interdisciplinary Communication; Patient Care Team; Intersectoral Collaboration; Orbital Neoplasms
PubMed: 38697143
DOI: 10.1055/a-2216-8879 -
International Ophthalmology Clinics 2018
Review
Topics: Diagnostic Techniques, Ophthalmological; Humans; Magnetic Resonance Imaging; Ophthalmologic Surgical Procedures; Orbital Neoplasms; Orbital Pseudotumor
PubMed: 29517650
DOI: 10.1097/IIO.0000000000000217 -
World Neurosurgery Jul 2020Primary dedifferentiated liposarcoma of the orbit is a rare condition. (Review)
Review
BACKGROUND
Primary dedifferentiated liposarcoma of the orbit is a rare condition.
CASE DESCRIPTION
A 41-year-old man presented with a history of right ophthalmalgia with eye movement and exophthalmos that had developed 2 months earlier. Neuroimages revealed a right orbital mass located above the superior rectus muscle. Tumor resection through the right frontal craniotomy was performed. Histopathologic findings showed the dedifferentiated liposarcoma.
CONCLUSIONS
Primary orbital dedifferentiated liposarcomas remain challenging for their diagnosis and standard treatment. Clinicians should keep in mind the possibility of liposarcoma with orbital tumors.
Topics: Adult; Humans; Liposarcoma; Male; Orbital Neoplasms
PubMed: 32339743
DOI: 10.1016/j.wneu.2020.04.069 -
Die Ophthalmologie Feb 2023
Topics: Humans; Orbital Diseases; Orbital Neoplasms
PubMed: 35394197
DOI: 10.1007/s00347-022-01607-5 -
Current Opinion in Otolaryngology &... Aug 2015The management of orbital tumours has evolved significantly over the last two decades, as the body of knowledge about these tumours grows and new techniques are... (Review)
Review
PURPOSE OF REVIEW
The management of orbital tumours has evolved significantly over the last two decades, as the body of knowledge about these tumours grows and new techniques are introduced that reduce surgical morbidity. The purpose of this review is to highlight and evaluate the most recent advancements in the management of these tumours.
RECENT FINDINGS
Several recent retrospective series emphasize the broad range of pathologic processes that can arise within the orbit. In addition, there have been a number of recent studies describing advances in endonasal endoscopic techniques for resection of orbital tumours.
SUMMARY
This articles summarizes the current opinion regarding the management of orbital tumours. Recent studies reviewing the range of diseases that affect the orbit and technical advances are summarized.
Topics: Decompression, Surgical; Endoscopy; Humans; Orbital Neoplasms; Plastic Surgery Procedures; Surgical Flaps
PubMed: 26101874
DOI: 10.1097/MOO.0000000000000173 -
Ophthalmic Plastic and Reconstructive... 2019To review the clinical features of orbital and choroidal metastases from urothelial carcinomas of the urinary tract among cases reported in the literature, and to... (Review)
Review
PURPOSE
To review the clinical features of orbital and choroidal metastases from urothelial carcinomas of the urinary tract among cases reported in the literature, and to describe a case of orbital metastasis from bladder cancer presenting as apparent internuclear ophthalmoplegia.
METHODS
Case reports of orbital and choroidal metastases from urothelial carcinomas published in the literature from 1965 to 2018 were reviewed. Data collected included patient demographics, cancer stage and primary site, time to onset of ocular symptoms, length of presenting ocular symptoms, types of primary ocular symptoms, diagnostic imaging, histology, systemic and ocular treatments, and survival time.
RESULTS
Twenty-eight cases of urothelial carcinoma with metastasis to the orbit or choroid were reviewed. Men were significantly more likely to suffer from this condition than women (p = 0.011). The average age of presentation with orbital symptoms was 63 years, with an average time of 19 months between primary cancer diagnosis and onset of orbital symptoms. Twenty-two patients had metastasis to the orbit and 6 to the choroid. In 4 cases, ocular deficits secondary to orbital and/or choroidal metastases were the initial presenting symptoms in patients with previously undiagnosed urothelial carcinoma. The most commonly noted primary ocular symptoms and signs consisted of decreased visual acuity, decreased ocular motility, proptosis, and diplopia. Average survival from onset of ocular symptoms was 4.67 months.
CONCLUSIONS
Urothelial carcinoma may metastasize to the orbit or choroid; furthermore, its presentation may mimic internuclear ophthalmoplegia. It is recommended that any patient with visual symptoms and known urothelial cancer should undergo expedited workup for metastatic disease.
Topics: Biopsy; Carcinoma, Transitional Cell; Humans; Neoplasm Staging; Orbit; Orbital Neoplasms; Tomography, X-Ray Computed; Urologic Neoplasms
PubMed: 30489454
DOI: 10.1097/IOP.0000000000001256 -
Archives of Iranian Medicine Feb 2015At an estimated incidence of 2 cases per million persons per year, osteosarcoma is the most common primary malignant bone tumor in children and adults, excluding...
At an estimated incidence of 2 cases per million persons per year, osteosarcoma is the most common primary malignant bone tumor in children and adults, excluding hematopoietic intraosseous tumors. Orbital metastases of osteosarcoma are very rare. Only 5 cases of orbital metastasis of osteosarcoma previously reported in the literature. We report the case of a 19-year-old man with known history of osteosarcoma of right distal femur who presented with acute visual loss and progressive protrusion of his left eye. Orbital CT scan and MRI revealed orbital mass eroding orbital walls and intracranial invasion. He underwent superotemporal orbitotomy for debulking of orbital mass. Histopathological examination (HPE) of the specimen was reported as metastatic osteosarcoma with extensive tumor necrosis. Then he underwent adjuvant chemotherapy and palliative radiotherapy. Although orbital metastasis of osteosarcoma is a rare event, it seems it has had an increasing trend recently. so, making efforts to palliate the patient's symptoms by multidisciplinary teamwork and proper interaction among ophthalmologist, orthopedic surgeons and oncologists is necessary.
Topics: Humans; Male; Necrosis; Neoplasm Metastasis; Ophthalmologic Surgical Procedures; Orbit; Orbital Neoplasms; Osteosarcoma; Surgical Flaps; Tomography, X-Ray Computed; Young Adult
PubMed: 25644802
DOI: No ID Found -
Survey of Ophthalmology 2017Peripheral nerve sheath tumors of the orbit and ocular adnexa are a rare group of neoplasms hallmarked by nonspecific clinical presentations, variable tumor locations,... (Review)
Review
Peripheral nerve sheath tumors of the orbit and ocular adnexa are a rare group of neoplasms hallmarked by nonspecific clinical presentations, variable tumor locations, challenging therapeutic efforts, and occasional diagnostic dilemmas. We review these tumor types and provide an updated summary on their clinical, histopathologic, radiological, and emerging molecular features.
Topics: Diagnosis, Differential; Global Health; Humans; Magnetic Resonance Imaging; Morbidity; Nerve Sheath Neoplasms; Ophthalmologic Surgical Procedures; Orbital Neoplasms; Tomography, X-Ray Computed
PubMed: 27570221
DOI: 10.1016/j.survophthal.2016.08.002 -
Canadian Journal of Ophthalmology.... Dec 2020
Topics: Humans; Orbital Neoplasms; Teratoma
PubMed: 32853589
DOI: 10.1016/j.jcjo.2020.06.019 -
Survey of Ophthalmology 2019The orbit can harbor mass lesions of various cellular origins. The symptoms vary considerably according to the nature, location, and extent of the disease and include... (Review)
Review
The orbit can harbor mass lesions of various cellular origins. The symptoms vary considerably according to the nature, location, and extent of the disease and include common signs of proptosis, globe displacement, eyelid swelling, and restricted eye motility. Although radiological imaging tools are improving, with each imaging pattern having its own differential diagnosis, orbital mass lesions often pose a diagnostic challenge. To provide an accurate, specific, and sufficiently comprehensive diagnosis, to optimize clinical management and estimate prognosis, pathological examination of a tissue biopsy is essential. Diagnostic orbital tissue biopsy is obtained through a minimally invasive orbitotomy procedure or, in selected cases, fine needle aspiration. The outcome of successful biopsy, however, is centered on its representativeness, processing, and interpretation. Owing to the often small volume of the orbital biopsies, artifacts in the specimens should be limited by careful peroperative tissue handling, fixation, processing, and storage. Some orbital lesions can be characterized on the basis of cytomorphology alone, whereas others need ancillary molecular testing to render the most reliable diagnosis of therapeutic, prognostic, and predictive value. Herein, we review the diagnostic algorithm for orbital mass lesions, using clinical, radiological, and pathological recommendations, and discuss the methods and potential pitfalls in orbital tissue biopsy acquisition and analysis.
Topics: Biopsy, Fine-Needle; Diagnosis, Differential; Humans; Orbital Neoplasms
PubMed: 31276737
DOI: 10.1016/j.survophthal.2019.06.006