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Applied Microbiology and Biotechnology Aug 2014Pseudomonas putida is widely distributed in nature and is capable of degrading various organic compounds due to its high metabolic versatility. The survival capacity of... (Review)
Review
Pseudomonas putida is widely distributed in nature and is capable of degrading various organic compounds due to its high metabolic versatility. The survival capacity of P. putida stems from its frequent exposure to various endogenous and exogenous oxidative stresses. Oxidative stress is an unavoidable consequence of interactions with various reactive oxygen species (ROS)-inducing agents existing in various niches. ROS could facilitate the evolution of bacteria by mutating genomes. Aerobic bacteria maintain defense mechanisms against oxidative stress throughout their evolution. To overcome the detrimental effects of oxidative stress, P. putida has developed defensive cellular systems involving induction of stress-sensing proteins and detoxification enzymes as well as regulation of oxidative stress response networks. Genetic responses to oxidative stress in P. putida differ markedly from those observed in Escherichia coli and Salmonella spp. Two major redox-sensing transcriptional regulators, SoxR and OxyR, are present and functional in the genome of P. putida. However, the novel regulators FinR and HexR control many genes belonging to the E. coli SoxR regulon. Oxidative stress can be generated by exposure to antibiotics, and iron homeostasis in P. putida is crucial for bacterial cell survival during treatment with antibiotics. This review highlights and summarizes current knowledge of oxidative stress in P. putida, as a model soil bacterium, together with recent studies from molecular genetics perspectives.
Topics: Gene Expression Regulation, Bacterial; Gene Regulatory Networks; Oxidants; Oxidative Stress; Pseudomonas putida; Stress, Physiological
PubMed: 24957251
DOI: 10.1007/s00253-014-5883-4 -
The Science of the Total Environment Oct 2022Enzyme-based bioremediation is a simple, cost-effective, and environmentally friendly method for isolating and removing a wide range of environmental pollutants. This... (Review)
Review
Enzyme-based bioremediation is a simple, cost-effective, and environmentally friendly method for isolating and removing a wide range of environmental pollutants. This study is a comprehensive review of recent studies on the oxidation of pollutants by biological oxidation methods, performed individually or in combination with other methods. The main bio-oxidants capable of removing all types of pollutants, such as organic and inorganic molecules, from fungi, bacteria, algae, and plants, and different types of enzymes, as well as the removal mechanisms, were investigated. The use of mediators and modification methods to improve the performance of microorganisms and their resistance under harsh real wastewater conditions was discussed, and numerous case studies were presented and compared. The advantages and disadvantages of conventional and novel immobilization methods, and the development of enzyme engineering to adjust the content and properties of the desired enzymes, were also explained. The optimal operating parameters such as temperature and pH, which usually lead to the best performance, were presented. A detailed overview of the different combination processes was also given, including bio-oxidation in coincident or consecutive combination with adsorption, advanced oxidation processes, and membrane separation. One of the most important issues that this study has addressed is the removal of both organic and inorganic contaminants, taking into account the actual wastewaters and the economic aspect.
Topics: Biodegradation, Environmental; Environmental Pollutants; Oxidants; Oxidation-Reduction; Wastewater; Water Pollutants, Chemical
PubMed: 35772531
DOI: 10.1016/j.scitotenv.2022.157026 -
The Science of the Total Environment Mar 2023Recently, Fenton-like systems have been widely explored and applied for the removal of organic matter from wastewater. Two-dimensional (2D) MXene-based materials exhibit... (Review)
Review
Recently, Fenton-like systems have been widely explored and applied for the removal of organic matter from wastewater. Two-dimensional (2D) MXene-based materials exhibit excellent adsorption and catalysis capacity for organic pollutants removal, which has been reported widely. However, there is no summary on the application of MXene-based materials in Fenton-like systems for organic matter removal. In this review, four types of MXene-based materials were introduced, including 2D MXene, MXene/Metal complex, MXene/Metal oxide complex, and MXene/3D carbon material complex. In addition, the Fenton-like system usually consists of adsorption and degradation processes. The oxidation process might contain hydrogen peroxide (HO) or persulfate (PS) oxidants. This review summarizes the performance and mechanisms of organic pollutants adsorption and oxidants activation by MXene-based materials systematically. Finally, the existing problems and future research directions of MXene-based materials are proposed in Fenton-like wastewater treatment systems.
Topics: Wastewater; Hydrogen Peroxide; Water Pollutants, Chemical; Oxidants; Oxidation-Reduction
PubMed: 36464059
DOI: 10.1016/j.scitotenv.2022.160539 -
Water Research Nov 2022Studies that promote chemical oxidation by permanganate (MnO; Mn(VII)) as a viable technology for water treatment and environmental purification have been quickly... (Review)
Review
Studies that promote chemical oxidation by permanganate (MnO; Mn(VII)) as a viable technology for water treatment and environmental purification have been quickly accumulating over the past decades. Various methods to activate Mn(VII) have been proposed and their efficacy in destructing a wide range of emerging organic contaminants has been demonstrated. This article aims to present a state-of-art review on the development of Mn(VII) activation methods, including photoactivation, electrical activation, the addition of redox mediators, carbonaceous materials, and other chemical agents, with a particular focus on the potential activation mechanism and critical influencing factors. Different reaction mechanisms are involved in activated Mn(VII) oxidation processes, including the generation of reactive intermediates derived from Mn(VII) (e.g., Mn(III), Mn(V), and Mn(VI)) or activators (e.g., intermediates of redox mediators and Ru catalysts), reactive oxygen species (ROS) (e.g., •OH, O, and O), as well as electron transfer from organics to Mn(VII) via catalysts as the electron mediator. Except •OH that is generated as one of co-oxidants in UV/Mn(VII) process, other reactive species are relatively mild oxidants, which are more selective toward organic substrates and highly tolerant toward various water matrices (e.g., inorganic ions and natural organic matter) compared to strongly oxidizing radical species. Therefore, activated Mn(VII) oxidation processes show a good prospect for efficient removal of target contaminants in natural and complex environmental matrices. However, there are some disputes about the dominant reactive species generated in these processes, and their identification methods may be not appropriate, causing serious confusion in the mechanistic understanding. So, further efforts are still needed to fill the knowledge gap and also to address the application challenges of these technologies.
Topics: Manganese Compounds; Oxides; Oxidation-Reduction; Water Purification; Oxidants; Catalysis
PubMed: 36279614
DOI: 10.1016/j.watres.2022.119265 -
Molecules (Basel, Switzerland) Feb 2022Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by burning of fossil fuels, wood and other organic materials. BaP as group I carcinogen... (Review)
Review
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by burning of fossil fuels, wood and other organic materials. BaP as group I carcinogen shows mutagenic and carcinogenic effects. One of the important mechanisms of action of (BaP) is its free radical activity, the effect of which is the induction of oxidative stress in cells. BaP induces oxidative stress through the production of reactive oxygen species (ROS), disturbances of the activity of antioxidant enzymes, and the reduction of the level of non-enzymatic antioxidants as well as of cytokine production. Chemical compounds, such as vitamin E, curcumin, quercetin, catechin, cyanidin, kuromanin, berberine, resveratrol, baicalein, myricetin, catechin hydrate, hesperetin, rhaponticin, as well as taurine, atorvastatin, diallyl sulfide, and those contained in green and white tea, lower the oxidative stress induced by BaP. They regulate the expression of genes involved in oxidative stress and inflammation, and therefore can reduce the level of ROS. These substances remove ROS and reduce the level of lipid and protein peroxidation, reduce formation of adducts with DNA, increase the level of enzymatic and non-enzymatic antioxidants and reduce the level of pro-inflammatory cytokines. BaP can undergo chemical modification in the living cells, which results in more reactive metabolites formation. Some of protective substances have the ability to reduce BaP metabolism, and in particular reduce the induction of cytochrome (CYP P450), which reduces the formation of oxidative metabolites, and therefore decreases ROS production. The aim of this review is to discuss the oxidative properties of BaP, and describe protective activities of selected chemicals against BaP activity based on of the latest publications.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Biomarkers; Disease Susceptibility; Energy Metabolism; Gene Expression Regulation; Humans; Lipid Peroxidation; Molecular Structure; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species
PubMed: 35209168
DOI: 10.3390/molecules27041379 -
Water Research Feb 2024Molecular oxygen as a green, non-toxic, and inexpensive oxidant has displayed numerous advantages compared with other oxidants for more sustainable and environmentally... (Review)
Review
Molecular oxygen as a green, non-toxic, and inexpensive oxidant has displayed numerous advantages compared with other oxidants for more sustainable and environmentally benign pollutant degradation. Molecular oxygen activation stands as a groundbreaking approach in advanced oxidation processes, offering efficient environmental remediation with minimal environmental impact with the production of high-oxidation reactive oxygen species (ROS). The adaptability and energy efficiency of molecular oxygen activation significantly contribute to the progression of sustainable water remediation technologies. This review meticulously explores the principles and mechanisms of molecular oxygen activation, shedding light on the diverse ROS production pathways. Subsequently, this review comprehensively details contemporary activation approaches, including photocatalytic activation, electrocatalytic activation, piezoelectric activation, and photothermal activation, explicating their distinct activation mechanisms. Additionally, it delves into the promising applications of molecular oxygen activation in the degradation of water pollutants, primary air pollutants, and volatile organic compounds, providing an in-depth analysis of the associated degradation pathways and mechanisms. Moreover, this review also addresses the imminent challenges and emerging opportunities in environmental remediation. It is envisioned that this comprehensive analysis will spur ongoing exploration and innovation in the use of molecular oxygen activation for environmental remediation and beyond.
Topics: Reactive Oxygen Species; Environmental Restoration and Remediation; Environmental Pollutants; Air Pollutants; Oxidants; Oxygen
PubMed: 38159543
DOI: 10.1016/j.watres.2023.121075 -
Journal of the American Chemical Society Dec 2019The enantioselective, vicinal diamination of alkenes represents one of the stereocontrolled additions that remains an outstanding challenge in organic synthesis. A...
The enantioselective, vicinal diamination of alkenes represents one of the stereocontrolled additions that remains an outstanding challenge in organic synthesis. A general solution to this problem would enable the efficient and selective preparation of widely useful, enantioenriched diamines for applications in medicinal chemistry and catalysis. In this article, we describe the first enantioselective, diamination of simple alkenes mediated by a chiral, enantioenriched organoselenium catalyst together with a bistosyl urea as the bifunctional nucleophile and fluorocollidinium tetrafluoroborate as the stoichiometric oxidant. Diaryl, aryl-alkyl, and alkyl-alkyl olefins bearing a variety of substituents are all diaminated in consistently high enantioselectivities but variable yields. The reaction likely proceeds through a Se(II)/Se(IV) redox catalytic cycle reminiscent of the dichlorination reported previously. Furthermore, the -stereospecificity of the transformation shows promise for highly enantioselective diaminations of alkenes with no strong steric or electronic bias.
Topics: Alkenes; Amination; Catalysis; Diamines; Organoselenium Compounds; Oxidants; Oxidation-Reduction; Stereoisomerism; Urea
PubMed: 31742399
DOI: 10.1021/jacs.9b11261 -
Accounts of Chemical Research Feb 2015CONSPECTUS: One of the biggest challenges for humanity in the 21st century is easy access to purified and potable water. The presence of pathogens and toxins in water... (Review)
Review
CONSPECTUS: One of the biggest challenges for humanity in the 21st century is easy access to purified and potable water. The presence of pathogens and toxins in water causes more than two million deaths annually, mostly among children under the age of five. Identifying and deploying effective and sustainable water treatment technologies is critical to meet the urgent need for clean water globally. Among the various agents used in the purification and treatment of water, iron-based materials have garnered particular attention in view of their special attributes such as their earth-abundant and environmentally friendly nature. In recent years, higher-valent tetraoxy iron(VI) (Fe(VI)O4(2-), Fe(VI)), commonly termed, ferrate, is being explored for a broad portfolio of applications, including a greener oxidant in synthetic organic transformations, a water oxidation catalyst, and an efficient agent for abatement of pollutants in water. The use of Fe(VI) as an oxidant/disinfectant and further utilization of the ensuing iron(III) oxides/hydroxide as coagulants are other additional attributes of ferrate for water treatment. This multimodal action and environmentally benign character of Fe(VI) are key advantages over other commonly used oxidants (e.g., chlorine, chlorine dioxide, permanganate, hydrogen peroxide, and ozone). This Account discusses current state-of-the-art applications of Fe(VI) and the associated unique chemistry of these high-valence states of iron. The main focus centers around the description and salient properties of ferrate species involving various electron transfer and oxygen-atom transfer pathways in terms of presently accepted mechanisms. The mechanisms derive the number of electron equivalents per Fe(VI) (i.e., oxidation capacity) in treating various contaminants. The role of pH in the kinetics of the reactions and in determining the removal efficiency of pollutants is highlighted; the rates of competing reactions of Fe(VI) with itself, water, and the contaminants, which are highly pH dependent, determine the optimum pH range of maximum efficacy. The main emphasis of this account is placed on cases where various modes of ferrate action are utilized, including the treatment of nitrogen- and sulfur-containing waste products, antibiotics, viruses, bacteria, arsenic, and heavy metals. For example, the oxidative degradation of N- and S-bearing contaminants by Fe(VI) yields either Fe(II) or Fe(III) via the intermediacy of Fe(IV) and Fe(V) species, respectively (e.g., Fe(VI) → Fe(IV) → Fe(II) and Fe(VI) → Fe(V) → Fe(III)). Oxidative transformations of antibiotics such as trimethoprim by Fe(VI) generate products with no residual antibiotic activity. Disinfection and inactivation of bacteria and viruses can easily be achieved by Fe(VI). Advanced applications involve the use of ferrate for the degradation of cyanobacteria and microcystin originating from algal blooms and for covalently embedding arsenic and heavy metals into the structure of formed magnetic iron(III) oxides, therefore preventing their leaching. Applications of state-of-the-art analytical techniques, namely, in situ Mössbauer spectroscopy, rapid-freeze electron paramagnetic resonance, nuclear forward scattering of synchrotron radiation, and mass spectrometry will enhance the mechanistic understanding of ferrate species. This will make it possible to unlock the true potential of ferrates for degrading emerging toxins and pollutants, and in the sustainable production and use of nanomaterials in an energy-conserving environment.
Topics: Green Chemistry Technology; Iron; Oxidants; Water Microbiology; Water Pollutants, Chemical; Water Purification
PubMed: 25668700
DOI: 10.1021/ar5004219 -
Free Radical Biology & Medicine Jan 2019Biomolecule (lipid and protein) oxidation products formed in plant cells exposed to photooxidative stress play a crucial role in the retrograde signaling and oxidative...
Biomolecule (lipid and protein) oxidation products formed in plant cells exposed to photooxidative stress play a crucial role in the retrograde signaling and oxidative damage. The oxidation of biomolecules initiated by reactive oxygen species is associated with formation of organic (alkyl, peroxyl and alkoxyl) radicals. Currently, there is no selective and sensitive technique available for the detection of organic radicals in plant cells. Here, based on the analogy with animal cells, immuno-spin trapping using spin trap, 5,5-dimethyl-1-pyrroline N-oxide (DMPO) was used to image organic radicals in Arabidopsis leaves exposed to high light. Using antibody raised against the DMPO nitrone adduct conjugated with the fluorescein isothiocyanate, organic radicals were imaged by confocal laser scanning microscopy. Organic radicals are formed predominantly in the chloroplasts located at the periphery of the cells and distributed uniformly throughout the grana stack. Characterization of protein radicals by standard immunological techniques using anti-DMPO antibody shows protein bands with apparent molecular weights of 32 and 34 kDa assigned to D1 and D2 proteins and two protein bands below the D1/D2 band with apparent molecular weights of 23 and 18 kDa and four protein bands above the D1/D2 band with apparent molecular weights of 41, 43, 55 and 68 kDa. In summary, imaging of organic radicals by immuno-spin trapping represents selective and sensitive technique for the detection of organic radicals that might help to clarify mechanistic aspects on the role of organic radicals in the retrograde signaling and oxidative damage in plant cell.
Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Lipids; Oxidation-Reduction; Oxidative Stress; Peroxides; Proteins; Reactive Oxygen Species; Spin Labels; Spin Trapping
PubMed: 30352303
DOI: 10.1016/j.freeradbiomed.2018.10.428 -
Water Research Jun 2022Recently, bisulfite-activated permanganate (MnO; Mn(VII)) process has attracted considerable attention as a novel class of advanced oxidation technology for destruction... (Review)
Review
Recently, bisulfite-activated permanganate (MnO; Mn(VII)) process has attracted considerable attention as a novel class of advanced oxidation technology for destruction of organic contaminants in water. However, disputes over the underlying activation mechanism as well as reactive species generated in the Mn(VII)/bisulfite system remain for a long period due to the fairly complex chemistry involved in this system. This article aims to present a critical review on scientific development of the Mn(VII)/bisulfite system, with particular focus on the generation and contribution of various reactive intermediates. Both reactive manganese species (RMnS) (i.e., soluble Mn(III), Mn(V), and Mn(VI)) and radical species (primarily SO) are identified as the oxidizing components responsible for enhanced degradation of organic contaminants by the Mn(VII)/bisulfite system. Bisulfite plays a dual role of being an activating agent for reactive intermediates generation and acting as a complexing agent to stabilize RMnS. Solution chemistry (e.g., the [Mn(VII)]/[bisulfite] molar ratio, solution pH, the type of contaminants, ligands, and water matrix components) greatly impacts the generation and consumption of RMnS and radicals, thus influencing the degradation kinetics and pathways of organics. Particularly, dissolved oxygen (DO) is a vital factor for driving the oxidation of organics since the absence of DO can block the generation of SO and meantime causes the consumption of RMnS by excess SO as a strong reductant. Interestingly, ferrate (FeO, Fe(VI)) and hexavalent chromium (CrO/HCrO, Cr(VI)) that are high-valent metal oxyanions analogous to Mn(VII) can be activated by bisulfite via a similar pathway (i.e. both high-valent metal-oxo intermediates and reactive radicals are involved). Furthermore, key knowledge gaps are identified and future research needs are proposed to address the potential challenges encountered in practical application of the Mn(VII)/bisulfite oxidation technology.
Topics: Decontamination; Manganese Compounds; Oxidation-Reduction; Oxidative Stress; Oxides; Sulfites; Water; Water Pollutants, Chemical
PubMed: 35358879
DOI: 10.1016/j.watres.2022.118331