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The Journal of the American Academy of... Jul 2021Chondrosarcoma is the second most common primary bone tumor, with >90% of cases representing the primary conventional subtype. In addition to arising de novo,...
Chondrosarcoma is the second most common primary bone tumor, with >90% of cases representing the primary conventional subtype. In addition to arising de novo, conventional chondrosarcoma can arise secondary to a benign underlying lesion, such as enchondroma or osteochondroma. Symptoms are often characterized by focal, dull, aching pain to the affected region. Grade is a well-recognized prognostic factor in these tumors. Grade I lesions/atypical cartilaginous tumors rarely metastasize, rarely recur, and have a 10-year survival rate of >80%. By contrast, grade III lesions are associated with a poor prognosis with the highest local recurrence rates, a lung metastasis rate of >50%, and a 10-year survival rate of <30%. The standard treatment of high-grade conventional chondrosarcoma is complete surgical resection with wide margin. However, low-grade lesions may be amenable to curettage plus or minus adjuvant local treatment. Conventional chondrosarcoma does not respond to chemotherapy or standard radiation doses. Adjuvant treatment can be beneficial for some subtypes such as chemotherapy for dedifferentiated and mesenchymal chondrosarcoma and radiation additionally for mesenchymal chondrosarcoma. Emerging radiation technologies may also play a useful role in treating tumors in anatomically complex areas such as the spine or pelvis.
Topics: Bone Neoplasms; Chondrosarcoma; Curettage; Humans; Neoplasm Recurrence, Local; Osteochondroma; Prognosis; Retrospective Studies
PubMed: 33595238
DOI: 10.5435/JAAOS-D-20-01188 -
Cutis Nov 2021Exostosis is a type of benign bone tumor in which trabecular (spongy) bone overgrows its normal border in a nodular pattern. When the growth occurs under the nail bed,...
Exostosis is a type of benign bone tumor in which trabecular (spongy) bone overgrows its normal border in a nodular pattern. When the growth occurs under the nail bed, it is termed subungual exostosis or Dupuytren exostosis. This condition may mimic other bony abnormalities such as an osteochondroma and may present with nail deformities with or without pain. For this reason, a biopsy of the lesion is necessary to rule out a precancerous growth. In rare cases, pediatric patients may have subungual exostosis, as demonstrated in our case.
Topics: Bone Neoplasms; Child; Exostoses; Humans; Nail Diseases; Nails; Osteochondroma
PubMed: 35100532
DOI: 10.12788/cutis.0380 -
Joint Bone Spine May 2022
Topics: Bone Neoplasms; Cartilage, Articular; Humans; Osteochondroma; Soft Tissue Neoplasms
PubMed: 34971858
DOI: 10.1016/j.jbspin.2021.105321 -
Joint Bone Spine Dec 2023
Topics: Humans; Osteochondroma; Patella; Bone Neoplasms
PubMed: 37028642
DOI: 10.1016/j.jbspin.2023.105571 -
Clinics in Podiatric Medicine and... Apr 2021Bone tumors of the foot are an uncommon finding. Most tumors are found incidentally on imaging and are benign. Care must be taken although due to the aggressive nature... (Review)
Review
Bone tumors of the foot are an uncommon finding. Most tumors are found incidentally on imaging and are benign. Care must be taken although due to the aggressive nature of malignant bone tumors that can occur in the calcaneus. Malignant lesions will more commonly present with symptoms of pain and swelling. Often misdiagnosed as soft tissue injuries, it is critical to be able to diagnose and treat these lesions early. Imaging plays an important role with plain films and advanced imaging. Surgical treatments can range from curettage with grafting to amputation for more aggressive lesions.
Topics: Bone Cysts; Bone Neoplasms; Calcaneus; Chondroblastoma; Chondroma; Chondrosarcoma; Ganglion Cysts; Giant Cell Tumor of Bone; Humans; Lipoma; Osteoblastoma; Osteochondroma; Osteoma; Osteosarcoma; Sarcoma, Ewing
PubMed: 33745653
DOI: 10.1016/j.cpm.2020.12.007 -
The Journal of Emergency Medicine Dec 2016
Topics: Adult; Bone Neoplasms; Humans; Humerus; Magnetic Resonance Imaging; Male; Osteochondroma; Radiography
PubMed: 27712895
DOI: 10.1016/j.jemermed.2016.07.105 -
The Pan African Medical Journal 2022
Topics: Bone Neoplasms; Humans; Osteochondroma; Ribs
PubMed: 35949455
DOI: 10.11604/pamj.2022.42.59.35217 -
Orthopedic Nursing 2020
Topics: Aged; Humans; Knee; Magnetic Resonance Imaging; Male; Osteochondroma
PubMed: 32218012
DOI: 10.1097/NOR.0000000000000644 -
Indian Pediatrics Feb 2021
Topics: Bone Neoplasms; Exostoses; Humans; Nail Diseases; Osteochondroma; Toes
PubMed: 33632969
DOI: No ID Found -
Radiologic Technology 2016Multiple hereditary exostoses (MHE), also known as multiple osteochondromas, is an autosomal dominant disease that results in the development of osteochondromas...
Multiple hereditary exostoses (MHE), also known as multiple osteochondromas, is an autosomal dominant disease that results in the development of osteochondromas throughout the body. The disease typically is diagnosed during childhood and requires lifelong monitoring and treatment of painful osteochondromas. Individuals with MHE must be monitored for complications that can arise and the potential malignant transformation of an osteochondroma into a chondrosarcoma. This article discusses the basic characteristics of MHE, genetic links, the role of medical imaging in diagnosis, and treatment options.
Topics: Diagnosis, Differential; Exostoses, Multiple Hereditary; Genetic Markers; Genetic Predisposition to Disease; Humans; Image Enhancement; Magnetic Resonance Imaging; Prevalence; Tomography, X-Ray Computed; Ultrasonography
PubMed: 26721841
DOI: No ID Found