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Current Medical Imaging 2021This article represents a review of the use of image-guided cryotherapy in the treatment of musculoskeletal tumor lesions. Cryotherapy is able to induce a lethal effect... (Review)
Review
BACKGROUND
This article represents a review of the use of image-guided cryotherapy in the treatment of musculoskeletal tumor lesions. Cryotherapy is able to induce a lethal effect on cancer cells through direct and indirect mechanisms. In this manuscript, we combined our experience with that of other authors who have published on this topic in order to provide indications on when to use cryotherapy in musculoskeletal oncology.
DISCUSSION
Image-Guided percutaneous cryotherapy is a therapeutic method now widely accepted in the treatment of patients with musculoskeletal tumors. It can be used both for palliative treatments of metastatic bone lesions and for the curative treatment of benign bone tumors, such as osteoid osteoma or osteoblastoma. In the treatment of bone metastases, cryotherapy plays a major role in alleviating or resolving disease-related pain, but it has also been demonstrated that it can have a role in local disease control. In recent years, the use of cryotherapy has also expanded for the treatment of both benign and malignant soft tissue tumors.
CONCLUSION
Percutaneous cryotherapy can be considered a safe and effective technique in the treatment of benign and malignant musculoskeletal tumors. Cryotherapy can be considered the first option in benign tumor lesions, such as osteoid osteoma, and a valid alternative to radiofrequency ablation. In the treatment of painful bone metastases, it must be considered secondarily to other standard treatments (radiotherapy, bisphosphonate therapy, and chemotherapy) when they are no longer effective in controlling the disease or when they cannot be repeated (for example, radiotherapy).
Topics: Bone Neoplasms; Cryotherapy; Humans; Osteoblastoma; Osteoma, Osteoid; Soft Tissue Neoplasms
PubMed: 32842945
DOI: 10.2174/1573405616666200825162712 -
Hand Surgery & Rehabilitation Oct 2023Osteoid osteoma is a benign bone tumor usually arising in the diaphysis and metaphysis of the long bones, with male predominance (sex ratio, 2:1). Despite being the most... (Review)
Review
Osteoid osteoma is a benign bone tumor usually arising in the diaphysis and metaphysis of the long bones, with male predominance (sex ratio, 2:1). Despite being the most common bone tumor in the wrist, it is still an atypical location for this lesion. The usual presentation is pain that is exacerbated at night and relieved by aspirin or non-steroidal anti-inflammatory drugs. This presentation is not always the case in the wrist, which leads to numerous differential diagnoses and often a delay in definitive diagnosis and treatment. Various imaging modalities can confirm the presence of the tumor and guide the surgical approach. Resection is the gold-standard, with radiofrequency gaining popularity in recent years.
Topics: Humans; Male; Female; Osteoma, Osteoid; Wrist; Wrist Joint; Pain; Bone Neoplasms
PubMed: 37182838
DOI: 10.1016/j.hansur.2023.05.002 -
The Open Orthopaedics Journal 2017Osteoid osteoma is a benign bone tumour that mostly affects males in the second and third decade of their life. The lesion mainly occurs in long bones, usually in the... (Review)
Review
Osteoid osteoma is a benign bone tumour that mostly affects males in the second and third decade of their life. The lesion mainly occurs in long bones, usually in the femur and tibia, causing severe localized pain that is worse at night and responds to nonsteroidal anti-inflammatory drugs (NSAIDs). Diagnosis is usually made on the basis of history and radiographic findings. However, in more unusual locations as the hand and foot, diagnostic issues can arise. Treatment often includes complete removal of the tumor. We present a 22 year old male with osteoid osteoma involving the distal phalanx of the hallux. To our knowledge very few cases of great toe osteoid osteoma have been reported in the literature.
PubMed: 29151998
DOI: 10.2174/1874325001711011066 -
Foot and Ankle Surgery : Official... Dec 2015Osteoid osteomas are responsible for 10% of benign bone tumours. Treatment typically involves surgical excision or radio frequency ablation. The aim of this systematic... (Review)
Review
BACKGROUND
Osteoid osteomas are responsible for 10% of benign bone tumours. Treatment typically involves surgical excision or radio frequency ablation. The aim of this systematic review is to evaluate reported cases of foot and ankle osteoid osteomas.
METHODS
We conducted a systematic review of the literature using the online databases Medline and EMBASE. We included studies reporting osteoid osteoma diagnosed either radiologically or histologically.
RESULTS
94 studies were included reporting 223 cases; 70.5% were male, mean age was 23 years, 69% reported night pain and 72% responded to NSAIDs. The commonest affected bone was the talus. CT scan was the most useful radiological investigation and MRI missed the diagnosis in 34% of cases. The majority of patients underwent surgical excision but an increasing trend of ablation therapy was demonstrated.
CONCLUSIONS
A high index of suspicion based on salient history and appropriate imaging are essential for timely identification and treatment.
Topics: Ankle; Bone Neoplasms; Foot; Humans; Osteoma, Osteoid
PubMed: 26564722
DOI: 10.1016/j.fas.2015.04.005 -
Der Orthopade Jun 2017Osteoid osteoma is the third most common benign bone tumor and typically induces pain that is worse at night. (Review)
Review
BACKGROUND
Osteoid osteoma is the third most common benign bone tumor and typically induces pain that is worse at night.
OBJECTIVE
To identify the epidemiological, pathogenetic, histological and radiological characteristics of osteoid osteoma and to present the broad variety of treatment options.
MATERIAL AND METHODS
This review article summarizes relevant clinical studies and meta-analyses on this topic.
RESULTS
Osteoid osteoma is characterized by a central nidus smaller than 1.5 cm in diameter with surrounding bone sclerosis. In the majority of cases, the tumor occurs in the long bones of the lower extremities and is predominantly manifested in patients aged between 5 and 25 years. Pain is mediated by prostaglandins, which stimulate afferent peripheral nerve fibers. Besides plain radiographs, thin-section computed tomography represents the gold standard of diagnostics but should be complemented by magnetic resonance or nuclear medicine imaging modalities. The conservative treatment consists of long-term therapy with non-steroidal anti-inflammatory drugs. Minimally invasive radiofrequency ablation of the nidus is the current operative treatment of choice.
CONCLUSION
Success rates of radiofrequency ablation and other minimally invasive procedures are high while treatment costs and length of hospital stay are low. Thus, open surgical curettage is reserved for rare indications and en bloc excision of the nidus should only be performed in cases of recurrent lesions.
Topics: Adolescent; Adult; Bone Neoplasms; Bone and Bones; Child; Child, Preschool; Cross-Sectional Studies; Diagnosis, Differential; Humans; Osteoma, Osteoid; Pain; Prostaglandins; Tomography, X-Ray Computed; Young Adult
PubMed: 28447111
DOI: 10.1007/s00132-017-3428-0 -
RoFo : Fortschritte Auf Dem Gebiete Der... Sep 2021
Topics: Bone Neoplasms; Cervix Uteri; Female; Humans; Image-Guided Biopsy; Osteoma, Osteoid; Radiofrequency Ablation; Tomography, X-Ray Computed
PubMed: 33772498
DOI: 10.1055/a-1408-9921 -
Orthopedic Reviews Sep 2018Osteoid osteoma is a benign bone-forming tumor with hallmark of tumor cells directly forming mature bone. Osteoid osteoma accounts for around 5% of all bone tumors and...
Osteoid osteoma is a benign bone-forming tumor with hallmark of tumor cells directly forming mature bone. Osteoid osteoma accounts for around 5% of all bone tumors and 11% of benign bone tumors with a male predilection. It occurs predominantly in long bones of the appendicular skeleton. According to Musculoskeletal Tumor Society staging system for benign tumors, osteoid osteoma is a stage-2 lesion. It is classified based on location as cortical, cancellous, or subperiosteal. Nocturnal pain is the most common symptom that usually responds to salicyclates and non-steroidal anti-inflammatory medications. CT is the modality of choice not only for diagnosis but also for specifying location of the lesion, . cortical sub periosteal or medullary. Non-operative treatment can be considered as an option since the natural history of osteoid osteoma is that of spontaneous healing. Surgical treatment is an option for patients with severe pain and those not responding to NSAIDs. Available surgical procedures include radiofrequency (RF) ablation, CT-guided percutaneous excision and resection.
PubMed: 30370032
DOI: 10.4081/or.2018.7496 -
RoFo : Fortschritte Auf Dem Gebiete Der... Sep 2019
Topics: Bone Neoplasms; Child; Cryosurgery; Diagnosis, Differential; Humans; Laser Therapy; Microwaves; Osteoma, Osteoid; Radiofrequency Ablation; Regional Blood Flow; Ultrasonography, Interventional
PubMed: 31430784
DOI: 10.1055/a-0943-1561 -
Skeletal Radiology Nov 2020Osteoid osteoma (OO), a small bone tumor relatively common in young subjects, frequently involves the hip. In addition to typical findings, we emphasize unsuspected... (Review)
Review
Osteoid osteoma (OO), a small bone tumor relatively common in young subjects, frequently involves the hip. In addition to typical findings, we emphasize unsuspected clinical and imaging features including painless OO causing limping gait, non-visibility of totally mineralized nidus, absence of hyperostosis or adjacent edema, and recurrence at distance from the initial location. We also discuss the option of medical treatment for some cases of deep hip locations.
Topics: Adolescent; Bone Neoplasms; Humans; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Osteoma, Osteoid; Tomography, X-Ray Computed
PubMed: 32561955
DOI: 10.1007/s00256-020-03515-8 -
The Israel Medical Association Journal... Aug 2022
Topics: Bone Neoplasms; Fingers; Humans; Osteoma, Osteoid; Upper Extremity
PubMed: 35972009
DOI: No ID Found