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Journal of Dentistry For Children... Jan 2017Multifocal epithelial hyperplasia is a rare disease associated with human papilloma virus types 13 and 32. Diagnosis is based on clinical and histopathological findings,...
Multifocal epithelial hyperplasia is a rare disease associated with human papilloma virus types 13 and 32. Diagnosis is based on clinical and histopathological findings, and most lesions are asymptomatic and regress spontaneously with time. The purpose of this paper is to describe a five-year-old girl who presented with multiple intraoral lesions on the buccal mucosa and tongue, which regressed spontaneously in 15 months.
Topics: Child, Preschool; Female; Focal Epithelial Hyperplasia; Humans; Lip; Mouth Diseases; Mouth Mucosa; New South Wales; Oral Health; Papilloma; Rare Diseases; Tongue
PubMed: 28387191
DOI: No ID Found -
Veterinary Microbiology Feb 2024The family Papillomaviridae includes a plethora of viral species infecting virtually all vertebrates excluding amphibians, with astonishing impact on human and animal... (Review)
Review
The family Papillomaviridae includes a plethora of viral species infecting virtually all vertebrates excluding amphibians, with astonishing impact on human and animal health. Although more than 250 species have been described in humans, the total number of papillomaviruses (PVs) discovered in animals does not reach up to this number. In animals, PV infections are mostly asymptomatic or can cause variable clinical conditions ranging from self-limiting papillomas and other cutaneous and mucosal benign lesions to cancer. Most of animal PV types have been discovered in cattle, dogs, horses, and cats with other farm host species remaining overlooked. In particular, the number of PV types so far identified in sheep is limited. This paper comprehensively reviews ovine PVs features, including viral taxonomy and evolution; genome organization; viral tropism and pathogenesis; macroscopical features and histopathological patterns, as well as available diagnostics tools. Data are critically presented and discussed in terms of impact on veterinary and public health. The development of future dedicated research is also discussed.
Topics: Animals; Deltapapillomavirus; Papilloma; Papillomaviridae; Papillomavirus Infections; Sheep; Sheep Diseases; Virulence
PubMed: 38160507
DOI: 10.1016/j.vetmic.2023.109955 -
Pathologica Mar 2017Papillomas are uncommon tumors of the sinonasal tract histologically derived from the Schneiderian membrane. Three distinctive variants are described, the exophytic, the... (Review)
Review
Papillomas are uncommon tumors of the sinonasal tract histologically derived from the Schneiderian membrane. Three distinctive variants are described, the exophytic, the inverting and the oncocytic types. On physical examination, their appearance varies from exophytic-fungiform seen in the exophytic variant, to polypoid-papillary in both the inverting and oncocytic variant. The presence of an asymptomatic mass or epistaxis and unilateral nasal obstruction are the typical presenting symptoms. Clinically they tend to recur and, although benign, they may erode the bone laminas by pressure, especially the inverting type, causing proptosis and other co-morbidities. Malignant transformation is seen both synchronously, on a pre-existing papilloma, and metachronously after several recurrences of papilloma. Schneiderian papillomas are at a date a topic of controversy regarding their etiology, pathogenesis and biological behavior. Furthermore, histologic criteria to assess dysplasia and malignant transformation are ill-defined. The present study aims to comparatively review the histologic types of papillomas, their etiology, the currently available criteria for malignant transformation, their treatment and prognosis.
Topics: Cell Transformation, Neoplastic; Humans; Nasal Mucosa; Neoplasm Recurrence, Local; Nose Neoplasms; Papilloma; Prognosis
PubMed: 28635991
DOI: No ID Found -
American Journal of Respiratory and... Aug 2020
Topics: Aged, 80 and over; Female; Humans; Papilloma; Tracheal Neoplasms
PubMed: 32352835
DOI: 10.1164/rccm.201911-2147IM -
Veterinary Pathology Nov 2014
Topics: Animals; Animals, Domestic; Cattle; Deltapapillomavirus; Keratinocytes; Papilloma; Papillomavirus Infections; Skin Neoplasms
PubMed: 25362100
DOI: 10.1177/0300985814541706 -
Indian Journal of Dermatology,... 2019
Topics: Adult; Humans; Lymphedema; Male; Papilloma
PubMed: 29697069
DOI: 10.4103/ijdvl.IJDVL_763_17 -
Anesthesiology Nov 2014
Topics: Airway Management; Airway Obstruction; Anesthesia, Inhalation; Child; Female; Humans; Laryngeal Neoplasms; Papilloma; Radiography; Voice Disorders
PubMed: 23872934
DOI: 10.1097/ALN.0b013e3182a35336 -
Cirugia Pediatrica : Organo Oficial de... Jul 2016Vesical tumors of infancy are of a low incidence and isolated clinical cases exist, and therefore there are no protocols regarding treatment and monitoring. In addition,...
INTRODUCTION
Vesical tumors of infancy are of a low incidence and isolated clinical cases exist, and therefore there are no protocols regarding treatment and monitoring. In addition, the histological criteria used until now are the ones in the WHO 2004 guidelines.
CLINICAL CASE
A 11 year old boy with non-specific abdominal pain. Upon abdominal ultrasound a tumor is observed near the left ureteral orifice, and proceeding with Thulium laser vaporization, a histological diagnosis is made: vesical urothelial papilloma.
COMMENTS
Different diagnostic and therapeutic methods are discussed, with particular emphasis on the importance of a correct diagnosis due to risk of confusion with carcinomas. Despite benign, there is a risk of malignant progression and we recommend pursuing clinical follow-ups and periodical ultrasounds, performing cystoscopy in case of suspicious findings on ultrasound.
Topics: Child; Cystoscopy; Humans; Laser Therapy; Male; Papilloma; Thulium; Urinary Bladder Neoplasms
PubMed: 28393510
DOI: No ID Found -
European Archives of... Jan 2023Papilloma is a common benign epithelial tumor of the respiratory tract in adults. Its histological structure and immune environment vary from site to site. This study...
OBJECTIVES
Papilloma is a common benign epithelial tumor of the respiratory tract in adults. Its histological structure and immune environment vary from site to site. This study investigated the disease characteristics and prognostic differences of papillomas at various primary locations.
METHODS
Clinical data was collected from patients with adult glossal root and hypopharyngeal papilloma admitted to our tertiary referral center between January 2010 and December 2020, and compared with patients with laryngeal papilloma. Differences in age, sex, smoking, alcohol consumption, single or multiple lesions, surgical methods, immunohistochemical indexes, Ki-67 and p16, were analyzed in patients with different primary papilloma sites.
RESULTS
A total of 84 cases of glossal root papilloma, 51 cases of hypopharyngeal papilloma, and 51 cases of laryngeal papilloma were included. Differential analysis between groups showed that there were statistically significant differences in age, sex, smoking, single and multiple lesions, and surgical methods in the different primary sites. Ki-67 expression in laryngeal papilloma was higher than that in glossal root and hypopharyngeal papilloma. There was no significant difference in p16 expression in the three groups. In terms of prognosis, laryngeal papilloma is more likely to relapse than glossal root or hypopharyngeal papilloma, and the recurrence time is shorter.
CONCLUSIONS
As the largest clinical study of papilloma in different primary locations, this study found that the clinical characteristics and postoperative recurrence of papilloma of the glossal root and hypopharynx differ from those of papilloma of the larynx. This finding supports the current clinical experience in treating papillomas in different locations and facilitates the development of clinical treatment plans.
Topics: Adult; Humans; Ki-67 Antigen; Neoplasm Recurrence, Local; Laryngeal Neoplasms; Papilloma
PubMed: 35939058
DOI: 10.1007/s00405-022-07575-5 -
Head and Neck Pathology Mar 2016Low-grade epithelial proliferations of the sinonasal tract include Schneiderian papillomas, respiratory epithelial adenomatoid hamartoma, seromucinous hamartoma and... (Review)
Review
Low-grade epithelial proliferations of the sinonasal tract include Schneiderian papillomas, respiratory epithelial adenomatoid hamartoma, seromucinous hamartoma and low-grade non-intestinal adenocarcinoma. There is considerable overlap in their clinical presentation, endoscopic appearance, and imaging features. Although well-described diagnostic criteria exist, a definitive diagnosis may be difficult to reach on a small biopsy. Schneiderian papillomas are divided into fungiform, inverted, and oncocytic types, each with characteristic clinical and morphological features. The latter two may progress to malignancy. The majority are still considered to be HPV-related. Two lesions are designated as hamartomas, but their pathogenesis remains uncertain, with inflammatory and neoplastic origins proposed. Respiratory epithelial adenomatoid hamartoma is increasingly being recognized for its association with chronic rhinosinusitis and olfactory cleft site of origin. Seromucinous hamartoma has gained attention in recent years and overlaps with both respiratory epithelial adenomatoid hamartoma and low-grade non-intestinal adenocarcinoma. Controversy surrounds their distinction, particularly from low-grade adenocarcinoma. The latter generally is cured by complete excision, with a 26 % risk of recurrence but rare metastases and deaths from disease.
Topics: Adenocarcinoma; Diagnosis, Differential; Hamartoma; Humans; Papilloma; Paranasal Sinus Diseases; Paranasal Sinus Neoplasms
PubMed: 26830403
DOI: 10.1007/s12105-016-0691-z