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Current Drug Metabolism 2018Traditional Persian Medicine (TPM) was the prevailing practice of medicine in the Eurasia region up through the 18th century, a practice of medicine stemming back to... (Review)
Review
INTRODUCTION
Traditional Persian Medicine (TPM) was the prevailing practice of medicine in the Eurasia region up through the 18th century, a practice of medicine stemming back to Hippocrates and to the 5000 year old civilization of the region. It is a school of medicine which touches on many a delicate points which may seem unimaginable within the realm of modern allopathic medicine. This practice of ancient medicine besides shedding light on various possible theoretical modern day disorders serves as a vast resource for therapeutics. In this paper, we present study of the manuscripts of this ancient medical practice in search of symptom presentations coinciding with presentation of multiple sclerosis (MS).
MATERIAL & METHOD
This paper represents a comprehensive search through TPM texts and manuscripts with the intention to seek possible clues on MS from potentially valuable age-old resources. We predominantly focused our search on the works of five eminent physicians of Medieval Persia: Avicenna (980-1037 AD), Haly Abbas (949-982 AD), Rhazes (865-925 AD), Averroes (1126-1198 AD) and Jorjani (1042-1137 AD).
RESULTS
In this paper, the authors attempt a theory and conclude with high probability that a conjunction of a series of signs, symptoms found in TPM texts under the terms khadar, isterkha and falej form the symptoms and the disease pattern of modern day MS. This theory draws upon existent similarities in terms of disease pathology, disease patterns and predisposing factors seen between MS and the related morbidities within Persian Medicine.
CONCLUSION
We recommend further examinations of such potentially valuable long-standing resources, examining the diagnoses and treatments as set forth by Persian Medicine through international collaboration within the global scientific community.
Topics: History, Ancient; History, Medieval; Humans; Medicine, Traditional; Multiple Sclerosis; Paralysis; Paresis; Paresthesia; Persia
PubMed: 28758579
DOI: 10.2174/1389200218666170728113523 -
Agri : Agri (Algoloji) Dernegi'nin... Jul 2023Herpes zoster (HZ) is a segmental vesicular eruption, pain, and sensorial symptoms. Segmental motor weakness can rarely be seen as a complication of HZ. Here, we present...
Herpes zoster (HZ) is a segmental vesicular eruption, pain, and sensorial symptoms. Segmental motor weakness can rarely be seen as a complication of HZ. Here, we present two cases of motor paresis associated with HZ, case 1 was L2 and L3 segmental motor paresis with femoral neuropathy and case 2 was L5 and S1 segmental motor paresis with sensorial ganglion involvement. In both cases after electrotherapy, exercise program, and medication for pain, there were no motor weakness and pain. Zoster motor paresis is a rare complication that responds to treatment and physicians should be careful about its presence in clinical follow-up.
Topics: Humans; Paresis; Herpes Zoster; Pain; Lower Extremity; Upper Extremity
PubMed: 37493485
DOI: 10.14744/agri.2021.70846 -
Nederlands Tijdschrift Voor Geneeskunde Aug 2018A 38-year-old woman presented with a 1-week history of progressive headache and acute onset of left-sided hemiparesis. Neurological examination showed bradyphrenia and...
A 38-year-old woman presented with a 1-week history of progressive headache and acute onset of left-sided hemiparesis. Neurological examination showed bradyphrenia and intermittent left hemiparesis. Brain neuroimaging revealed cavernous sinus thrombosis, subdural empyema, pathological vessel-wall enhancement of the right middle cerebral artery and ischaemia in the right striatum. Cavernous sinus thrombophlebitis with secondary vasculitis and ischaemic stroke was diagnosed. Bacteraemia due to Streptococcus intermedius from a jaw infection was found and she received antibiotic treatment. At six-month follow-up, her symptoms had improved remarkably. Clinical signs such as progressive headache, which does not respond to analgesics, subtle cranial nerve palsy and increased infectious parameters should alert the clinician to conduct appropriate neuroimaging studies. Early initiation of effective antibiotic treatment in these cases is essential and can change the course of the illness and improve prognosis.
Topics: Adult; Brain; Cavernous Sinus Thrombosis; Female; Headache; Humans; Paresis
PubMed: 30212024
DOI: No ID Found -
Minerva Surgery Dec 2022Recurrent laryngeal nerve (RLN) paresis is a rare but serious complication in thyroid surgery. Intermittent intraoperative nerve monitoring (IONM) was thought to prevent...
BACKGROUND
Recurrent laryngeal nerve (RLN) paresis is a rare but serious complication in thyroid surgery. Intermittent intraoperative nerve monitoring (IONM) was thought to prevent paresis of the RLN, but until today data are not conclusive. Our objective was to confirm the hypothesis that IONM can reduce paresis of RLN compared to nerve visualization alone. Therefore, we examined one of the largest cohorts ever evaluated of a tertiary referral center for endocrine surgery undergoing thyroid surgery for benign thyroid disease.
METHODS
Overall, 2097 patients who underwent thyroid surgery for benign thyroid disease in 2016 and 2017 were evaluated. RLN was identified by IONM or visualization only. Preoperative and postoperative laryngoscopic examination was used to evaluate RLN paresis. Patients' characteristics and perioperative data were extracted retrospectively.
RESULTS
Overall, 1963 patients (2720 nerves at risk [NAR]) were included in this study: 378 surgeries with IONM (560 NAR) and 1585 without IONM (2160 NAR). Transient and permanent RLN pareses were found in 13 (3.4%; NAR=2.3%) and one (0.3%; NAR=0.2%) nerve treated with IONM vs. 37 (2.3%; NAR=1.7%) and five (0.3%; NAR=0.2%) nerves without IONM (P=0.507; NAR P=0.654), respectively.
CONCLUSIONS
Using intermittent IONM, our retrospective study could not demonstrate a significant decrease of RLN pareses in patients undergoing thyroid surgery for benign thyroid disease. This is probably explained by the very low overall number of RLN pareses in our department. Nevertheless, because of patients' safety to avoid any bilateral RLN pareses, we recommend IONM in bilateral resections.
Topics: Humans; Recurrent Laryngeal Nerve; Recurrent Laryngeal Nerve Injuries; Thyroidectomy; Retrospective Studies; Monitoring, Intraoperative; Thyroid Diseases; Paresis
PubMed: 35230041
DOI: 10.23736/S2724-5691.22.09421-7 -
Journal of Neurologic Physical Therapy... Apr 2019The optimal characteristics of learning to promote recovery of walking have yet to be defined for the poststroke population. We examined characteristics of task practice... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND AND PURPOSE
The optimal characteristics of learning to promote recovery of walking have yet to be defined for the poststroke population. We examined characteristics of task practice that limit or promote learning of a novel locomotor pattern.
METHODS
Thirty-two persons with chronic hemiparesis were randomized to 2 conditions (constant and variable practice) and participated in two 15-minute sessions of split-belt treadmill walking. On day 1, subjects in the constant condition walked on the split-belt treadmill at a constant 2:1 speed ratio, while subjects in the variable condition walked on the split-belt treadmill at 3 different speed ratios. On day 2, both groups participated in 15 minutes of split-belt treadmill walking at the 2:1 speed ratio. Step length and limb phase symmetry metrics were measured to assess within-session learning (ie, adaptation) on day 1 and the ability to retain this new pattern of walking (ie, retention) on day 2.
RESULTS
The amount of adaptation on day 1 did not differ depending upon practice structure (constant and variable) for step length or limb phase (a)symmetry. The magnitude of reduction in asymmetry from day 1 to day 2 did not differ between groups for step and limb phase (a)symmetry.
DISCUSSION AND CONCLUSIONS
The results suggest that variable practice utilizing alternating belt speed ratios does not influence the ability of those with chronic stroke to adapt and retain a novel locomotor pattern. The effects of other forms of variable practice within other locomotor learning paradigms should be explored in those with chronic hemiparesis after stroke.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A257).
Topics: Adaptation, Physiological; Aged; Exercise Therapy; Female; Humans; Locomotion; Male; Middle Aged; Paresis; Practice, Psychological; Stroke; Stroke Rehabilitation; Treatment Outcome; Walking
PubMed: 30883495
DOI: 10.1097/NPT.0000000000000260 -
Tierarztliche Praxis. Ausgabe G,... Feb 2017This two-part review presents an overview of peripheral-limb pareses in cattle, which represent the most frequent bovine neurologic disorder and are mostly caused by... (Review)
Review
This two-part review presents an overview of peripheral-limb pareses in cattle, which represent the most frequent bovine neurologic disorder and are mostly caused by trauma of specific peripheral nerves. Occurrence, etiology, diagnosis, prognosis and therapy are presented. The second part of the review describes neuroanatomical details important for diagnostics, localization of the neuronal lesion within the lower motor neuron and classification of the grade of peripheral-nerve injury. Furthermore additional diagnostic tools are presented and prognosis, therapy and prevention of peripheral limb pareses in cattle are discussed.
Topics: Animals; Cattle; Cattle Diseases; Paresis; Peripheral Nerve Injuries; Peripheral Nerves; Prognosis
PubMed: 28116416
DOI: 10.15653/TPG-160453 -
Journal of Pain & Palliative Care... Sep 2014
Topics: Female; Humans; Migraine with Aura; Paresis
PubMed: 25313420
DOI: No ID Found -
International Journal of Rehabilitation... Sep 2018Mental practice (MP) is usually provided in combination with other therapies, and new developments for neurofeedback to support MP have been made recently. The... (Meta-Analysis)
Meta-Analysis Review
Mental practice (MP) is usually provided in combination with other therapies, and new developments for neurofeedback to support MP have been made recently. The objectives of this study were to evaluate the effectiveness of MP and to investigate the intervention characteristics including neurofeedback that may affect treatment outcome. The Cochrane Central Register of Controlled Trials, PubMed, Embase, KoreaMed, Scopus, Web of Science, PEDro, and CIRRIE were searched from inception to March 2017 for randomized controlled trials to assess the effect of MP for upper limb rehabilitation after stroke. Fugl-Meyer Assessment (FMA) was used as the outcome measure for meta-analysis. Twenty-five trials met the inclusion criteria, and 15 trials were eligible for meta-analysis. Among the trials selected for meta-analysis, MP was added to conventional therapy in eight trials or to modified constraint-induced movement therapy in one trial. The other trials provided neurofeedback to support MP: MP-guided neuromuscular electrical stimulation (NMES) in four trials and MP-guided robot-assisted therapy (RAT) in two trials. MP added to conventional therapy resulted in significantly higher FMA gain than conventional therapy alone. MP-guided NMES showed superior result than conventional NMES as well. However, the FMA gain of MP-guided RAT was not significantly higher than RAT alone. We suggest that MP is an effective complementary therapy either given with neurofeedback or not. Neurofeedback applied to MP showed different results depending on the therapy provided. This study has limitations because of heterogeneity and inadequate quality of trials. Further research is requested.
Topics: Electric Stimulation Therapy; Humans; Neurofeedback; Paresis; Robotics; Stroke; Stroke Rehabilitation; Upper Extremity
PubMed: 29912022
DOI: 10.1097/MRR.0000000000000298 -
Brain and Nerve = Shinkei Kenkyu No... Feb 2017Clinical manifestations of spinal epidural hematoma are presented, and the cases mimicking acute ischemic stroke have been reviewed from the literature. Many reports... (Review)
Review
Clinical manifestations of spinal epidural hematoma are presented, and the cases mimicking acute ischemic stroke have been reviewed from the literature. Many reports described the cases of spinal epidural hematoma with acute hemiparesis mimicking ischemic stroke in which intravenous thrombolytic treatment with recombinant tissue plasminogen activator was considered. A correct diagnosis of acute ischemic stroke must be made within 4.5 hours from the onset of symptoms, a relatively short window period. A spinal epidural hematoma is a potentially important stroke mimic in a wide variety of conditions that mimic a stroke. The literature review and discussion will emphasize allowing the distinction between these hemiparetic presentation of spinal epidural hematoma and acute ischemic stroke. A spinal epidural hematoma should be considered in the differential diagnosis of patients with acute onset of hemiparesis when associated with neck pain and signs of Horner's syndrome and Brown-Sēquard syndrome.
Topics: Diagnosis, Differential; Diagnostic Errors; Hematoma, Epidural, Spinal; Humans; Paresis; Stroke; Tissue Plasminogen Activator
PubMed: 28202820
DOI: 10.11477/mf.1416200652 -
Journal of Rehabilitation Medicine Apr 2016To evaluate the evidence for, and clinical relevance of, immediate and long-term effects of trunk restraint during reach-to-grasp training poststroke on movement... (Review)
Review
OBJECTIVE
To evaluate the evidence for, and clinical relevance of, immediate and long-term effects of trunk restraint during reach-to-grasp training poststroke on movement patterns and functional abilities within the framework of the International Classification of Functioning, Disability and Health.
DATA SOURCES
PubMed, Web of Science, CINAHL, Embase, PEDro, Cochrane Library (publication dates January 1985 to March 2015).
STUDY SELECTION
Randomized controlled trials comparing training using trunk restraint with any other exercise training.
DATA EXTRACTION
Data were extracted by one researcher and checked by two other researchers. The Cochrane Collaboration's tool for assessing risk of bias and the Physiotherapy Evidence Database scale were used by two researchers to assess study quality and risk of bias.
DATA SYNTHESIS
Eight studies met the inclusion criteria. Five studies found better recovery of movement patterns (trunk displacement, elbow extension, and/or shoulder flexion - body function/structure) at post-test in the experimental compared with the control groups. Functional abilities (activity/participation) improved more in the experimental groups in 3 studies at post-test. Long-term effects were found in one study after 4 weeks.
CONCLUSION
Trunk restraint has immediate and some long-term effects in adults with chronic stroke. However, these effects are not consistently clinically relevant when referring to minimal detectable change or minimal clinically important difference values.
Topics: Elbow Joint; Exercise Therapy; Hand Strength; Humans; Paresis; Range of Motion, Articular; Recovery of Function; Restraint, Physical; Shoulder Joint; Stroke; Stroke Rehabilitation; Torso
PubMed: 27008369
DOI: 10.2340/16501977-2077