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Environmental Research Mar 2022Based on the theory of biological optimal particle size, the most easily attached droplets for different organisms have different particle sizes. To achieve the best...
Based on the theory of biological optimal particle size, the most easily attached droplets for different organisms have different particle sizes. To achieve the best average particle size, the droplet size in the atomization field must be more uniform and attain a high the adhesion rate. Therefore, during the application process, not only the average particle size of the droplets but also the influence of the uniformity of the droplets in the spray field must be considered. In this study, 20 small-angle fan nozzles ranging from 20° to 40° are used as the research objects. The droplet size information in the atomization field is obtained using a laser particle size analyzer, and the droplet uniformity under different parameters is calculated. The results showed that within the range of the parameters selected in the experiment, the droplet size increased with an increase in the flow rate, and decreased with an increase in the pressure. In addition, the angle had little effect on the droplet size. Increasing the spray height, spray angle, and pressure, while reducing the equivalent outlet diameter of the nozzle was beneficial to improve the uniformity of droplets. The order of the degree of influence of the four parameters on the uniformity of the droplets was height > equivalent outlet diameter (r) > pressure > spray angle, and the influence weights were 51.1%, 37.1%, 7.8%, 4.1%; 48.4%, 37.6%, 10%, and 4%. Under the condition of the parameter settings used in this experiment, the optimal atomization effect for the four intervals of 150-200 μm, 200-250 μm, 250-300 μm, and 300-400 μm was analyzed from the perspective of uniformity. The nozzle models with the best atomization effects in each interval were SS4003-0.3 MPa, SS4006-0.3 MPa, SS4008-0.3 MPa, and 633.512.30.CC-0.1 MPa.
Topics: Particle Size
PubMed: 34555405
DOI: 10.1016/j.envres.2021.112076 -
Food Research International (Ottawa,... Aug 2023High-resolution (HR) visual imaging and spectral imaging are common computer vision-based techniques used for food quality analysis and/or authentication based on the...
High-resolution (HR) visual imaging and spectral imaging are common computer vision-based techniques used for food quality analysis and/or authentication based on the interaction of light and material surface and/or composition. The particle size of ground spices is an important morphological feature that affects the physico-chemical properties of food products containing such particles. This study aimed to interpret the impact of particle size of ground spice on its HR visual profile and spectral imaging profile using ginger powder as a representative spice powder model. The results revealed an increase in the light reflection with the decrease of particle size of ginger powder, which was manifested by the lighter colour (higher percentage of the colour code with lighter yellow colour) of the HR visual image and stronger reflection with spectral imaging. The study also revealed that, in spectral imaging, the influence of the particle size of ginger powder increased with rising wavelengths. Finally, the results indicated a relationship between spectral wavelengths, ginger particle size, and other natural variables of the products which might be generated from cultivation to processing. Ultimately, the impact of natural variables arising during the food production process on the physico-chemical properties of the product should be fully considered or even additionally evaluated prior to the application of specific food quality and/or authentication analytical techniques.
Topics: Zingiber officinale; Particle Size; Powders; Spices
PubMed: 37316086
DOI: 10.1016/j.foodres.2023.113023 -
Sensors (Basel, Switzerland) Jun 2023We established an experimental apparatus by combining polarized light scattering and angle-resolved light scattering measurement technology to rapidly identify the shape...
We established an experimental apparatus by combining polarized light scattering and angle-resolved light scattering measurement technology to rapidly identify the shape of an individual aerosol particle. The experimental data of scattered light of Oleic acid, rod-shaped Silicon dioxide, and other particles with typical shape characteristics were analyzed statistically. To better study the relationship between the shape of particles and the properties of scattered light, the partial least squares discriminant analysis (PLS-DA) method was used to analyze the scattered light of aerosol samples based on the size screening of particles, and the shape recognition and classification method of the individual aerosol particle was established based on the analysis of the spectral data after nonlinear processing and grouping by particle size with the area under the receiver operating characteristic curve (AUC) as reference. The experimental results show that the proposed classification method has a good discrimination ability for spherical, rod-shaped, and other non-spherical particles, which can provide more information for atmospheric aerosol measurement, and has application value for traceability and exposure hazard assessment of aerosol particles.
Topics: Particle Size; Nephelometry and Turbidimetry; Aerosols
PubMed: 37420631
DOI: 10.3390/s23125464 -
Journal of Pharmaceutical Sciences Oct 2014Particle size reduction can be used for enhancing the dissolution of poorly water-soluble drugs in order to enhance bioavailability. In nanosuspensions, the particle... (Review)
Review
Particle size reduction can be used for enhancing the dissolution of poorly water-soluble drugs in order to enhance bioavailability. In nanosuspensions, the particle size of the drug is reduced to nanometer size. Nanosuspensions after downstream processing into drug products have successfully shown its impact on formulation design, the augmentation of product life cycle, patent life, and therapeutic efficacy. Formulation considerations for the nanosuspension formulation, its processing into a solid form, and aspects of material characterization are discussed. Technology assessments and feasibility of upstream processes for nanoparticle creation, and subsequently transformation into a drug product via the downstream processes have been reviewed. This paper aims to bridge formulation and process considerations along with patent reviews and may provide further insight into understanding the science and the white space. An analysis of current patent outlook and future trends is described to fully understand the limitations and opportunities in intellectual property generation.
Topics: Nanotechnology; Particle Size; Patents as Topic; Pharmaceutical Preparations
PubMed: 25099918
DOI: 10.1002/jps.24098 -
Journal of Hazardous Materials Feb 2022We investigated the effect of polysulfide formation on properties of biologically produced elemental sulfur (S) crystals, which are produced during biological...
We investigated the effect of polysulfide formation on properties of biologically produced elemental sulfur (S) crystals, which are produced during biological desulfurization (BD) of gas. The recent addition of an anoxic-sulfidic reactor (AnSuR) to the BD process resulted in agglomerated particles with better settleability for S separation. In the AnSuR, polysulfides are formed by the reaction of bisulfide (HS) with S and are subsequently oxidized to S in a gas-lift reactor. Therefore, sulfur particles from the BD are shaped (i.e. morphology and particle size) both by formation and dissolution. We assessed the reaction of HS with S particles in anoxic, abiotic experiments in a batch reactor using two S samples from industrial BD reactors. Under these conditions, the sulfur particle surface became coarser and more porous, and in addition the smallest particles disappeared. Agglomerates initially fell apart but were reformed at a later stage. Moreover, we found different observed polysulfide formation rates for each S sample, which was related to the initial morphology and size. Our findings show that particle properties can be controlled abiotically and that settleability of S is increased by increasing both the HS-S ratio and retention time.
Topics: Oxidation-Reduction; Particle Size; Sulfides; Sulfur
PubMed: 34823957
DOI: 10.1016/j.jhazmat.2021.127696 -
International Journal of Pharmaceutics Mar 2021Milling is widely used in various industries to tailor the particle size distribution for desired attributes. The ability to predict milling behaviour by testing the...
Milling is widely used in various industries to tailor the particle size distribution for desired attributes. The ability to predict milling behaviour by testing the breakability of a small quantity of material is of great interest. In this paper, a widely available aerodynamic dispersion method, i.e. the Aero S disperser of Malvern Mastersizer 3000 has been evaluated for this purpose. This device is commonly used for dispersion of fine and cohesive powders, as the particles are accelerated and impacted at a bend, but here its use for assessing particle breakability is explored. The fluid flow field is modelled using one-way coupled Computational Fluid Dynamics approach, as the particle concentration is low, following which the particle impact velocity is calculated by Lagrangian tracking and used in the analysis of particle breakage. Experimental work on the breakability is carried out using aspirin, paracetamol, sucrose and α-lactose monohydrate particles. The relative shift in the specific surface area is determined and together with the calculated particle impact velocity and physical properties, they are used to calculate the breakability index. A good agreement is obtained with the single particle impact testing and aerodynamic dispersion by Scirocco disperser, indicating the breakability could also be inferred from this method.
Topics: Hydrodynamics; Lactose; Particle Size; Powders; Sucrose
PubMed: 33571623
DOI: 10.1016/j.ijpharm.2021.120365 -
Molecules (Basel, Switzerland) Feb 2021Magnetite (FeO) nanoparticles were synthesized using the chemical coprecipitation method. Several nanoparticle samples were synthesized by varying the concentration of...
Magnetite (FeO) nanoparticles were synthesized using the chemical coprecipitation method. Several nanoparticle samples were synthesized by varying the concentration of iron salt precursors in the solution for the synthesis. Two batches of nanoparticles with average sizes of 10.2 nm and 12.2 nm with nearly similar particle-size distributions were investigated. The average particle sizes were determined from the XRD patterns and TEM images. For each batch, several samples with different particle concentrations were prepared. Morphological analysis of the samples was performed using TEM. The phase and structure of the particles of each batch were studied using XRD, selected area electron diffraction (SAED), Raman and XPS spectroscopy. Magnetic hysteresis loops were obtained using a Lakeshore vibrating sample magnetometer (VSM) at room temperature. In the two batches, the particles were found to be of the same pure crystalline phase of magnetite. The effects of particle size, size distribution, and concentration on the magnetic properties and magneto thermic efficiency were investigated. Heating profiles, under an alternating magnetic field, were obtained for the two batches of nanoparticles with frequencies 765.85, 634.45, 491.10, 390.25, 349.20, 306.65, and 166.00 kHz and field amplitudes of 100, 200, 250, 300 and 350 G. The specific absorption rate (SAR) values for the particles of size 12.2 nm are higher than those for the particles of size 10.2 nm at all concentrations and field parameters. SAR decreases with the increase of particle concentration. SAR obtained for all the particle concentrations of the two batches increases almost linearly with the field frequency (at fixed field strength) and nonlinearly with the field amplitude (at fixed field frequency). SAR value obtained for magnetite nanoparticles with the highest magnetization is 145.84 W/g at 765.85 kHz and 350 G, whereas the SAR value of the particles with the least magnetization is 81.67 W/g at the same field and frequency.
Topics: Magnetite Nanoparticles; Particle Size; Temperature
PubMed: 33557107
DOI: 10.3390/molecules26040796 -
Wiley Interdisciplinary Reviews.... 2023Nanoemulsions (NEs) are emulsions with particle size of less than around 100 nm. Reviewing the literature, several reports are available on NEs, including preparation,... (Review)
Review
Nanoemulsions (NEs) are emulsions with particle size of less than around 100 nm. Reviewing the literature, several reports are available on NEs, including preparation, characterization, and applications of them. This review aims to brief challenges that researchers or formulators may encounter when working with NEs. For instance, when selecting NE components and identifying their concentrations, stability and safety of the preparation should be evaluated. When preparing an NE, issues over scale-up of the preparation as well as possible effects of the preparation process on the active ingredient need to be considered. When characterizing the NEs, the two major concerns are accuracy of the method and accessibility of the characterizing instrument. Also a highly efficient NE for clinical use to deliver the active ingredient to the target tissue with maximum safety profile is commonly sought. Throughout the review we also have tried to suggest approaches to overcome the challenges. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies.
Topics: Emulsions; Particle Size
PubMed: 37558229
DOI: 10.1002/wnan.1920 -
Nano Letters Mar 2022Particle size disparities suppress crystallization. However, soft deformable nanogels can change the size of the larger particles in suspension and crystallize even at a...
Particle size disparities suppress crystallization. However, soft deformable nanogels can change the size of the larger particles in suspension and crystallize even at a high initial size-polydispersity. Using neutron scattering with contrast variation, the response of individual nanogels in crowded environments was probed, and an increase of the parameter describing size-polydispersity was found, which is often interpreted as deformation. Here, computer simulations are used to generate deformed nanogels and the corresponding form factor. The data are fitted with the spherical model used to analyze scattering data. The fits show the same qualitative increase of the parameter related to the size-polydispersity with increasing particle deformation. Starting from the simulated deformed spheres, we also reproduce experimental scattering data. A further analysis of the particle shows that the size disparities between nanogels do not increase significantly. In contrast, their shapes strongly vary from one nanogel to the other.
Topics: Crystallization; Nanogels; Particle Size
PubMed: 35258981
DOI: 10.1021/acs.nanolett.2c00120 -
Water Environment Research : a Research... May 2020Grit chambers are installed at the headworks of a water resource recovery facility (WRRF) to reduce the impact of grit particles to the equipment and processes...
Grit chambers are installed at the headworks of a water resource recovery facility (WRRF) to reduce the impact of grit particles to the equipment and processes downstream. This settling process should thus be designed and operated in an efficient way. Despite the importance of knowing settling characteristics for design and operation of grit chambers, previous grit definitions have been based only on particle size characteristics, and not on settling velocities. Thus, this study presents an evaluation of the performance of two promising settling velocity characterization methods, ViCAs and elutriation, to characterize wastewater particles in view of the design and the optimization of the efficiency of the grit removal unit. PRACTITIONER POINTS: Settling characteristics are the governing parameter for grit chamber design. Since grit particles are vastly heterogeneous, it is preferred to measure these characteristics directly rather than to estimate them from particle size (and assumptions of density, form factor, …). More detailed settling information about grit particles can improve grit chamber design and estimation of removal performance. Adapted ViCAs and elutriation methods for faster settling particles allow studying the particle settling characteristics in a grit chamber. These methods are simple, fast, and cheap and only require small wastewater samples. A relationship was found between the influent TSS concentration and the location of the PSVD curve, with higher TSS concentrations corresponding to higher settling velocities. It was demonstrated that the dynamics of the wastewater characteristics under dry, wet, and snowmelt weather conditions influence grit settling characteristics.
Topics: Particle Size; Wastewater; Water Resources; Weather
PubMed: 31680372
DOI: 10.1002/wer.1268