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American Journal of Obstetrics &... Nov 2019
Topics: Cesarean Section; Chlorhexidine; Female; Humans; Povidone-Iodine; Pregnancy
PubMed: 33345846
DOI: 10.1016/j.ajogmf.2019.100039 -
Retina (Philadelphia, Pa.) Dec 2019
Topics: Humans; Intravitreal Injections; Patient Comfort; Povidone-Iodine
PubMed: 30908475
DOI: 10.1097/IAE.0000000000002503 -
American Journal of Ophthalmology Jan 2019
Topics: Conjunctivitis; Dexamethasone; Humans; Povidone-Iodine
PubMed: 30390919
DOI: 10.1016/j.ajo.2018.09.016 -
New Zealand Veterinary Journal Mar 2022The objective of this paper is to review the evidence for different methods of surgical hand preparation applicable to veterinary practice. Surgical hand preparation is... (Review)
Review
The objective of this paper is to review the evidence for different methods of surgical hand preparation applicable to veterinary practice. Surgical hand preparation is an essential step in performing surgery as a veterinarian. Recommended protocols and products for surgical hand preparation have varied since its inception in the late 1800s. Many factors must be considered when assessing the efficacy, safety, and users' compliance with any available product. Traditional scrub methods employing chlorhexidine gluconate or povidone-iodine have been compared to alcohol-based rub protocols with respect to immediate and prolonged efficacy, safety, compliance, requirements for theatre furniture, cost and water usage. Although much of the comparative data has been generated in human medical facilities, extrapolation of the data to veterinary surgery is appropriate. Considerations for veterinary practice are specifically discussed. Overall, the benefits of alcohol-based rubs indicate that this should be the preferred method of pre-surgical hand preparation for veterinarians in all types of practice.
Topics: Animals; Anti-Infective Agents, Local; Chlorhexidine; Ethanol; Hand Disinfection; Povidone-Iodine; Surgical Wound Infection
PubMed: 34586948
DOI: 10.1080/00480169.2021.1987348 -
Survey of Ophthalmology 2018Iodine has been recognized as an effective bactericide since the 1800s, and povidone-iodine (PI) solution has been applied to the ocular surface and periocular skin... (Review)
Review
Iodine has been recognized as an effective bactericide since the 1800s, and povidone-iodine (PI) solution has been applied to the ocular surface and periocular skin since the 1980s to prevent endophthalmitis in cataract surgery. In vitro, PI solution kills bacteria quickly at dilute concentrations (0.05%-1.0%). In many instances, PI kills bacteria more quickly at these dilute concentrations than more conventional (5%-10%) concentrations. This is due to greater availability of diatomic free iodine in dilute solution, the bactericidal component of PI. The toxicity of PI, both in vitro and clinically, has been shown to be related to concentration. Current American Academy of Ophthalmology and the European Society of Cataract and Refractive Surgeons recommendations regarding PI use suggest using 5% PI before surgery. An alternative dosing strategy uses dilute PI repetitively throughout cataract surgery (0.25% every 30 seconds). We review the povidone-iodine literature with attention to basic science and use of dilute PI.
Topics: Anti-Bacterial Agents; Cataract Extraction; Endophthalmitis; Eye Infections, Bacterial; Humans; Povidone-Iodine
PubMed: 29778494
DOI: 10.1016/j.survophthal.2018.05.002 -
British Dental Journal Jun 2020
Topics: Mouthwashes; Povidone-Iodine
PubMed: 32591671
DOI: 10.1038/s41415-020-1794-1 -
Eye (London, England) Oct 2021
Topics: Anti-Infective Agents, Local; Cataract Extraction; Humans; Povidone-Iodine
PubMed: 33594245
DOI: 10.1038/s41433-021-01447-8 -
British Dental Journal Sep 2020
Topics: Iodine; Povidone-Iodine
PubMed: 32917988
DOI: 10.1038/s41415-020-2127-0 -
Contact Dermatitis May 2021Allergy evaluation by patch testing with povidone-iodine (PVP-I) or iodine remains challenging, because current patch test preparations frequently lead to false-positive...
BACKGROUND
Allergy evaluation by patch testing with povidone-iodine (PVP-I) or iodine remains challenging, because current patch test preparations frequently lead to false-positive or irritant skin reactions.
OBJECTIVES
To investigate different preparations for iodine patch tests and to assess their clinical relevance with repeated open application tests (ROATs).
METHODS
We monocentrically analyzed 95 patients with suspected allergy to disinfectants in retrospect who underwent parallel iodine patch testing with four preparations: PVP-I 2% aq., 5% aq., 10% aq., and iodine 0.5% pet.
RESULTS
In 27 of 95 patients (28.4%), we found positive reactions to one of the four test preparations. After ROATs in 22 of these 27 positively tested individuals, only one patient was diagnosed with iodine allergy. In contrast, 31 of 95 patients (32.6%) showed irritant or questionable patch test reactions on day 2 (D2) and/or D3 and/or D7 to one or more test preparations. Testing with PVP-I 2% aq. resulted in the lowest number of doubtful skin reactions while detecting the single allergic patient.
CONCLUSION
PVP-I 2% aq. was found to be the optimal patch test preparation. In general, iodine allergy appears to be substantially overestimated, and positive patch test responses to iodine should prompt an urgent ROAT for confirmation before diagnosing iodine allergy.
Topics: Dermatitis, Allergic Contact; False Positive Reactions; Humans; Iodine; Patch Tests; Povidone-Iodine; Retrospective Studies
PubMed: 33306197
DOI: 10.1111/cod.13760 -
Romanian Journal of Ophthalmology 2021Endophthalmitis remains a serious complication following intraocular procedures. Preoperative prophylactic measures for endophthalmitis decrease the morbidity associated... (Review)
Review
Endophthalmitis remains a serious complication following intraocular procedures. Preoperative prophylactic measures for endophthalmitis decrease the morbidity associated with this disease and represent a standard of care prior to ophthalmic surgery. The literature supports as measures for ocular antisepsis: povidone-iodine solution for ocular surface preparation, chlorhexidine in patients with iodine allergy and application of topical antibiotics. Povidone-iodine is regarded as the most effective antiseptic associated with significant reduction in ocular surface bacterial counts. Currently, the recommended preoperative management is the application of 5% povidone-iodine solution in the conjunctival fornix, prior to surgery. This paper reviews the preoperative measures for ocular antisepsis, used in order to decrease the risk of culture-proven endophthalmitis.
Topics: Anti-Infective Agents, Local; Antisepsis; Conjunctiva; Endophthalmitis; Humans; Povidone-Iodine
PubMed: 34179575
DOI: 10.22336/rjo.2021.25