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The American Journal of Tropical... Oct 2018
Topics: Accidental Falls; Aged; Agriculture; Cataract; Female; Ghana; Humans; Hypertension; Poverty
PubMed: 30292244
DOI: 10.4269/ajtmh.18-0265 -
Indian Journal of Ophthalmology Jun 2018
Topics: Cataract; Humans; Lens, Crystalline; Male; Microscopy, Acoustic; Middle Aged
PubMed: 29786001
DOI: 10.4103/ijo.IJO_280_18 -
Journal Francais D'ophtalmologie May 2018
Topics: Cataract; Fundus Oculi; Humans; Male; Morocco; Treatment Refusal; Young Adult
PubMed: 29759651
DOI: 10.1016/j.jfo.2017.09.018 -
Nutrients Oct 2023Cataract, defined as the opacification of the lens that prevents clear vision, is a leading cause of vision loss and impairment worldwide. Elderly people comprise the... (Review)
Review
Cataract, defined as the opacification of the lens that prevents clear vision, is a leading cause of vision loss and impairment worldwide. Elderly people comprise the highest proportion of those suffering from this eye disease. According to the National Institute of Health (NIH), the risk of developing aged-related cataract (ARC) increases with every decade of life, starting from the age of 40. Despite progress in surgical treatment methods, life-style modifications may be beneficial in prevention or slowing down the progression of ARC. This systematic review aims to summarize studies on the significance of specific nutritional patterns, dietary products, vitamins, minerals, and carotenoids intake in the onset or progression of ARC. In this context, the presented paper thoroughly analyzes 24 articles, following the PRISMA guidelines. The results indicate significant protective effects of various dietary patterns, including the Korean balanced diet, vegetarian diet, "dairy products and vegetables", "traditional", "antioxidant", and "omega-3" patterns. Additionally, the consumption of fruits, vegetables, legumes, nuts, skimmed yoghurt, fish, coffee, and vitamins has shown positive effects on cataract incidence. Therefore, further research seems to be essential to gain a better understanding of these associations and to create uniform dietary recommendations for both the vulnerable population and ARC patients.
Topics: Aged; Animals; Humans; Vitamins; Diet; Cataract; Antioxidants; Vitamin A; Vegetables; Vitamin K
PubMed: 37960238
DOI: 10.3390/nu15214585 -
Birth Defects Research Jun 2017Neonatal cataracts remain the most common cause of visual loss in children worldwide and have diverse, often unknown, etiologies. This review summarizes current... (Review)
Review
Neonatal cataracts remain the most common cause of visual loss in children worldwide and have diverse, often unknown, etiologies. This review summarizes current knowledge about the detection, treatment, genetics, risk factors, and molecular mechanisms of congenital cataracts. We emphasize significant progress and topics requiring further study in both clinical cataract therapy and basic lens research. Advances in genetic screening and surgical technologies have improved the diagnosis, management, and visual outcomes of affected children. For example, mutations in lens crystallins and membrane/cytoskeletal components that commonly underlie genetically inherited cataracts are now known. However, many questions still remain regarding the causes, progression, and pathology of neonatal cataracts. Further investigations are also required to improve diagnostic criteria for determining the timing of appropriate interventions, such as the implantation of intraocular lenses and postoperative management strategies, to ensure safety and predictable visual outcomes for children. Birth Defects Research 109:734-743, 2017. © 2017 Wiley Periodicals, Inc.
Topics: Cataract; Cataract Extraction; Eye Diseases, Hereditary; Genetic Predisposition to Disease; Genetic Testing; Humans; Lens Implantation, Intraocular; Lens, Crystalline; Lenses, Intraocular; Risk Factors; Visual Acuity
PubMed: 28544770
DOI: 10.1002/bdr2.1050 -
Ageing Research Reviews Aug 2022Cataract is the leading cause of blindness worldwide and surgery is the only option to treat the disease. Although the surgery is considered to be relatively safe,... (Review)
Review
Cataract is the leading cause of blindness worldwide and surgery is the only option to treat the disease. Although the surgery is considered to be relatively safe, complications may occur in a subset of patients and access to ophthalmic care may be limited. Due to a growing and ageing population, an increase in cataract prevalence is expected and its management will become a socioeconomic challenge. Hence, there is a need for an alternative to cataract surgery. It is well known that oxidative stress is one of the main pathological processes leading to the generation of the disease. Antioxidant supplementation may, therefore, be a strategy to delay or to prevent the progression of cataract. Caffeine is a widely consumed high-potency antioxidant and may be of interest for the prevention of the disease. This review aims to give an overview of the anatomy and function of the lens, its antioxidant and reactive oxygen species (ROS) composition, and the role of oxidative stress in cataractogenesis. Also, the pharmacokinetics and -dynamics of caffeine will be described and the literature will be reviewed to give an overview of its anti-cataract potential and its possible role in the prevention of the disease.
Topics: Antioxidants; Caffeine; Cataract; Humans; Lens, Crystalline; Oxidative Stress
PubMed: 35690384
DOI: 10.1016/j.arr.2022.101664 -
Journal of Binocular Vision and Ocular... Oct 2023Childhood cataract is a complex condition requiring longitudinal care, including early diagnosis, timely referral to a specialist, early surgical intervention, and... (Review)
Review
Childhood cataract is a complex condition requiring longitudinal care, including early diagnosis, timely referral to a specialist, early surgical intervention, and dedicated postoperative care. Adherence to refractive correction and amblyopia therapy are critical for visual rehabilitation, even months to years after the cataract is removed. We review the impact of the social determinants of health on each step in the visual rehabilitation pathway for children with congenital and infantile cataracts. Children from socioeconomically marginalized backgrounds are more likely to experience delays in access to care and utilization of surgical services. They are also less likely to adhere to amblyopia therapy, with corresponding decrements in visual outcomes. Additional sociocultural factors, including parental stress, self-efficacy, and health literacy, pose barriers for these children. Standardizing clinical roles, improving health communication, managing parental stress, and implementing systemic policy changes may alleviate socioeconomic disparities in outcomes for children with cataracts.
Topics: Child; Humans; United States; Cataract Extraction; Amblyopia; Lens Implantation, Intraocular; Cataract; Visual Acuity
PubMed: 37931121
DOI: No ID Found -
Seminars in Ophthalmology 2014Diabetic patients are known to have an increased risk of cataract development and cataract surgery is a common surgical procedure for diabetic individuals. Cataract... (Review)
Review
Diabetic patients are known to have an increased risk of cataract development and cataract surgery is a common surgical procedure for diabetic individuals. Cataract extraction (CE) in diabetic patients as compared to non-diabetic patients is associated with higher risks of reported complications such as capsular contraction and opacification as well as post-surgical worsening of macular edema (ME) and diabetic retinopathy (DR). In this paper, we review the pathogenesis of diabetic cataract, the risk factors contributing to cataract complications as well as DR progression, and assess preventive measures and treatment options for DR and ME following CE.
Topics: Cataract; Cataract Extraction; Diabetes Complications; Disease Progression; Humans; Risk Factors
PubMed: 25325858
DOI: 10.3109/08820538.2014.959197 -
JAMA Ophthalmology Sep 2023
Topics: Child; Humans; Cataract Extraction; Lens, Crystalline; Glaucoma; Ophthalmology; Cataract
PubMed: 37590009
DOI: 10.1001/jamaophthalmol.2023.3804 -
The Veterinary Clinics of North... Dec 2017Examination of the lens is critical, particularly when evaluating horses with visual impairment or performing prepurchase examinations. To adequately evaluate the lens,... (Review)
Review
Examination of the lens is critical, particularly when evaluating horses with visual impairment or performing prepurchase examinations. To adequately evaluate the lens, the pupil must be pharmacologically dilated. A cataract is any lens opacity. The size, density, and position of a cataract determine the impact on vision. Cataracts may be congenital or inherited or occur secondary to trauma or equine recurrent uveitis. Surgical removal is the only treatment option for vision impairing cataracts, but careful selection of surgical candidates is critical for successful outcomes.
Topics: Animals; Cataract; Cataract Extraction; Diagnosis, Differential; Horse Diseases; Horses; Lens Diseases
PubMed: 29103558
DOI: 10.1016/j.cveq.2017.07.004