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Journal of Cutaneous and Aesthetic... 2023Pyogenic granuloma is a benign vascular tumor, with a tendency to bleed on manipulation. A young female presented to us with a disfiguring facial pyogenic granuloma. We...
Pyogenic granuloma is a benign vascular tumor, with a tendency to bleed on manipulation. A young female presented to us with a disfiguring facial pyogenic granuloma. We adopted a novel approach using pressure therapy to treat the same. The use of an elastic adhesive bandage reduced the size and vascularity of the lesion, following which laser ablation was done with minimal bleeding and scarring. This is a simple, inexpensive method to approach large and disfiguring pyogenic granulomas.
PubMed: 37383971
DOI: 10.4103/JCAS.JCAS_97_21 -
Archivos de La Sociedad Espanola de... Feb 2021A 46-year-old caucasian male with a history of chronic conjunctival hyperemia, presented at our clinic 5 years after he underwent the surgical procedure of cosmetic eye...
CLINICAL CASE
A 46-year-old caucasian male with a history of chronic conjunctival hyperemia, presented at our clinic 5 years after he underwent the surgical procedure of cosmetic eye whitening. On examination we observed pyogenic granuloma in the right eye; besides acute nongranulomatous anterior uveitis and necrotizing scleritis in both eyes.
RESULT
Complete clinical evaluation and full work-up exclusion of systemic diseases was done. The pyogenic granuloma was treated with surgical resection, as well as anterior uveitis and necrotizing scleritis were successfully treated with systemic corticoesteroids and methotrexate.
CONCLUSION
The surgical cosmetic eye whitening could have as complication the pyogenic granuloma in addition to necrotizing scleritis and nongranulomatous anterior uveitis; and be present 5 years after the procedure. The surgical resection is a successful treatment for this presentation of pyogenic granuloma.
PubMed: 33158667
DOI: 10.1016/j.oftal.2020.06.034 -
Dermatologic Therapy Jul 2021An increasing use of beta-blockers in dermatology has been described over the last 10 years, despite the fact that their use in diseases other than infantile... (Review)
Review
An increasing use of beta-blockers in dermatology has been described over the last 10 years, despite the fact that their use in diseases other than infantile hemangiomas is off-label. This review discusses the emerging role of topical beta-blockers in the treatment of infantile hemangioma, but also pyogenic granuloma, Kaposi sarcoma, wounds and nail paronychia. Data in literature demonstrate that topical beta-blockers are a safe and valid therapeutic option in numerous cutaneous diseases. Side effects are mainly restricted to the application site. Further studies and randomized trials may contribute to reinforce the role of topical beta-blockers in the dermatological armamentarium.
Topics: Adrenergic beta-Antagonists; Granuloma, Pyogenic; Humans; Sarcoma, Kaposi; Skin Diseases; Timolol
PubMed: 34075667
DOI: 10.1111/dth.15016 -
Lancet (London, England) Apr 2022
Topics: Diagnosis, Differential; Granuloma, Pyogenic; Humans; Sarcoma, Kaposi; Skin Neoplasms
PubMed: 26498707
DOI: 10.1016/S0140-6736(15)00467-5 -
International Journal of Dermatology Dec 2023
Topics: Humans; Granuloma, Pyogenic; Rituximab
PubMed: 37700737
DOI: 10.1111/ijd.16825 -
Ear, Nose, & Throat Journal Nov 2022
Topics: Ear Auricle; Ear, External; Granuloma, Pyogenic; Hemangioma; Humans
PubMed: 33236929
DOI: 10.1177/0145561320968924 -
Sultan Qaboos University Medical Journal May 2019
Topics: Adult; Arteriovenous Fistula; Arteriovenous Malformations; Granuloma, Pyogenic; Humans; India; Male
PubMed: 31538020
DOI: 10.18295/squmj.2019.19.02.017 -
National Journal of Maxillofacial... 2019Oral pyogenic granuloma or granuloma pyogenicum is a conspicuous lesion. The word pyogenic granuloma is a misterm since the situation is not related with pus and... (Review)
Review
Oral pyogenic granuloma or granuloma pyogenicum is a conspicuous lesion. The word pyogenic granuloma is a misterm since the situation is not related with pus and histologically does not exemplify a granuloma. An oral pyogenic granuloma is obvious to involve the gingiva generally. Extragingivally, it can present on the buccal mucosa, lips, tongue, and palate. A report of trauma is prevalent in such sites. The pathogenesis of the lesion is still unclear, although it was initially supposed to be a botryomycosis infection. It is suggested that etiology of pyogenic granuloma was the reaction of tissues to minor injury or chronic irritation, thus open a pathway for the entrance of nonspecific microorganisms, although microorganisms are not often expressed within the lesion. Hence, this review recapitulates all diverse concepts of pathogenesis associated with this most often and most mysterious lesion of the oral cavity.
PubMed: 31205381
DOI: 10.4103/njms.NJMS_55_18 -
Oral pyogenic granuloma: An 18-year retrospective clinicopathological and immunohistochemical study.Journal of Cutaneous Pathology Jul 2021Pyogenic granuloma (PG) is a lesion characterized by the proliferation of blood vessels, commonly affecting the skin and the mouth. We aimed to compare clinical,...
BACKGROUND
Pyogenic granuloma (PG) is a lesion characterized by the proliferation of blood vessels, commonly affecting the skin and the mouth. We aimed to compare clinical, microscopic, and immunohistochemical features of the two types of oral PG: lobular capillary hemangioma (LCH) and non-LCH (NLCH).
METHODS
Epidemiological and clinical data from 2000 to 2018 were collected from the archives of our institution, and histopathological sections of PG were reviewed. Immunohistochemical analyses (CD34, D2-40, SMA, mast cell, and Ki-67) were performed in 34 cases.
RESULTS
Sixty-two LCH and 107 non-LCH samples were included. The mean (±SD) age of the patients was 38.59 ± 16.96 years; 55.62% were female; 39.64% of cases occurred in the gingiva, 44% of the nodules were pedunculated, and 13.02% of patients reported a history of trauma. NLCH was more prevalent among older patients than LCH. The most prevalent site of LCH was the lips, while NLCH occurred more in the gingiva (P < 0.05). Epithelial atrophy, microvessels, SMA-positive areas, and Ki-67-positive nuclei were more prevalent in LCH (P < 0.05).
CONCLUSIONS
PG accounted for 2.25% of lesions archived in the pathology service and most cases were NLCH. LCH and NLCH exhibited clinicopathological differences in terms of age, site, epithelial atrophy, vascularization, and proliferation rate.
Topics: Actins; Adult; Biopsy; Case-Control Studies; Female; Gingiva; Granuloma, Pyogenic; Humans; Immunohistochemistry; Ki-67 Antigen; Lip; Male; Middle Aged; Mouth; Mouth Mucosa; Neovascularization, Pathologic; Prevalence; Retrospective Studies
PubMed: 33486806
DOI: 10.1111/cup.13970 -
The American Journal of Dermatopathology Feb 2023
Topics: Humans; Sarcoma, Kaposi; Granuloma, Pyogenic; Skin Neoplasms; Herpesvirus 8, Human; Diagnosis, Differential
PubMed: 36669084
DOI: 10.1097/DAD.0000000000002280