-
Progress in Neuro-psychopharmacology &... Aug 2023Identifying and integrating the neural correlates of suicidal ideation and behaviors is crucial to expand the knowledge and develop targeted strategies to prevent... (Review)
Review
Identifying and integrating the neural correlates of suicidal ideation and behaviors is crucial to expand the knowledge and develop targeted strategies to prevent suicide. This review aimed to describe the neural correlates of suicidal ideation, behavior and the transition between them, using different magnetic resonance imaging (MRI) modalities, providing an up-to-date overview of the literature. To be included, the observational, experimental, or quasi-experimental studies must include adult patients currently diagnosed with major depressive disorder and investigate the neural correlates of suicidal ideation, behavior and/or the transition using MRI. The searches were conducted on PubMed, ISI Web of Knowledge and Scopus. Fifty articles were included in this review: 22 on suicidal ideation, 26 on suicide behaviors and two on the transition between them. The qualitative analysis of the included studies suggested alterations in the frontal, limbic and temporal lobes in suicidal ideation associated with deficits in emotional processing and regulation, and in the frontal, limbic, parietal lobes, and basal ganglia in suicide behaviors associated with impairments in decision-making. Gaps in the literature and methodological concerns were identified and might be addressed in future studies.
Topics: Adult; Humans; Suicidal Ideation; Depressive Disorder, Major; Depression; Brain; Magnetic Resonance Imaging
PubMed: 37207727
DOI: 10.1016/j.pnpbp.2023.110799 -
Journal of Affective Disorders Jan 2022Suicidal ideation, a significant risk factor of suicide, is considered a potential trigger for intervention prior to self-harm or suicide; however, the prevalence of... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Suicidal ideation, a significant risk factor of suicide, is considered a potential trigger for intervention prior to self-harm or suicide; however, the prevalence of maternal suicidal ideation varied widely between studies. This review aims to synthesis the available evidence to estimate the prevalence of maternal suicidal ideation before and after pregnancy.
METHODS
We searched six English databases (PubMed, Web of Science, Embase, the Cochrane Library, PsycINFO, CINAHL) and three Chinese databases (China National Knowledge Infrastructure, Wang Fang, Chinese Biomedical Literature Databases) from database inceptions before August 31, 2020; and checked the reference list for relevant studies. Data in the included studies were used to calculate the prevalence of maternal suicidal ideation. Subgroup analysis and meta-regression were performed to detect the potential sources of heterogeneity.
RESULTS
6094 potentially studies were identified. 71 studies, including 23 cohort studies, 47 cross-sectional studies, and 1 RCT study, were included for final analysis. The total participants were 92146, with sample size ranged from 23 to 22118. The included studies were from 23 different countries distributing on six continents, most of the studies were conducted in Asia (n = 18), North America (n = 16), and South America (n = 15). The pooled prevalence of maternal suicidal ideation reported by eligible studies was 8% (95% CI 7-10%), with 10% in antenatal and 7% in postpartum. Prevalence significantly varied based on measuring tools, study design, study countries, and publication year, while prevalence was not conditional on the time-point assessment, sample size, and maternal age.
LIMITATION
Obvious heterogeneity and no standardization tools for measuring suicidal ideation may limit the results' interpretation.
CONCLUSION
Our systematic review reported the prevalence of suicidal ideation in pregnancy and postpartum was 8%. Future studies should establish standardization tools for measuring suicidal ideation and identify strategies of prevention and treatment.
Topics: Cross-Sectional Studies; Female; Humans; Postpartum Period; Pregnancy; Prevalence; Suicidal Ideation; Suicide
PubMed: 34600967
DOI: 10.1016/j.jad.2021.09.083 -
Current Topics in Behavioral... 2020Early thinking about cognitive process and suicidal behaviors tended to focus on the immediate situation surrounding the individual - typically the underlying...
Early thinking about cognitive process and suicidal behaviors tended to focus on the immediate situation surrounding the individual - typically the underlying psychiatric condition that was seen as leading to his or her distress. However, we now know that the cognitive processes involved in a range of suicidal thoughts and behaviors can exert a significant impact on the expression or development of these behaviors, even without an environmental stressor or psychiatric condition. In this chapter, we summarize theoretical perspectives that led to this realization and explore the current understanding of the link between cognition and suicide from recent research and clinical findings. We present these findings first by psychiatric disorder, then by cognitive domains, and finally by specific suicidal construct in order to highlight the importance of these factors in determining the role of cognition in the suicidal process.Within and across psychiatric disorders, certain cognitive processes - negativistic thinking, impulsivity, cognitive rigidity, and altered emotional processing - are frequently found to be linked to suicidal thoughts and behaviors. Overall cognitive performance, decreased processing speed, executive dysfunction, and negative biases in memory and attention have also been linked to suicidal thoughts and behaviors. However, these findings do not hold true for all populations. There seems to be a role both for cognitive distortions (such as hopelessness) and neurocognitive deficits (such as poor overall cognitive performance, slower processing speed, and executive dysfunction) in the suicidal process, which warrant further exploration both separately and together.
Topics: Cognition; Emotions; Humans; Memory; Suicidal Ideation; Suicide
PubMed: 32860213
DOI: 10.1007/7854_2020_162 -
The British Journal of Clinical... Nov 2022Suicidal ideation is a pervasive and painful experience that varies considerably in its phenomenology. Here, we consider how one key risk variable might inform our...
OBJECTIVES
Suicidal ideation is a pervasive and painful experience that varies considerably in its phenomenology. Here, we consider how one key risk variable might inform our understanding of variation in suicidal ideation: emotion-related impulsivity, the trait-like tendency towards unconstrained speech, behaviour, and cognition in the face of intense emotions. We hypothesized that emotion-related impulsivity would be tied to specific features, including severity, perceived lack of controllability, more rapidly fluctuating course, higher scores on a measure of acute suicidal affective disturbance, and more emotional and cognitive disturbance as antecedents.
METHODS
We recruited two samples of adults (Ns = 421, 221) through Amazon Mechanical Turk (MTurk), with oversampling of those with suicidal ideation. Both samples completed psychometrically sound self-report measures online to assess emotion- and non-emotion-related dimensions of impulsivity and characteristics of suicidal ideation.
RESULTS
One form of emotion-related impulsivity related to the severity, uncontrollability, dynamic course, and affective and cognitive precursors of ideation.
CONCLUSIONS
Despite limitations of the cross-sectional design and self-report measures, the current findings highlight the importance of specificity in considering key dimensions of impulsivity and suicidal ideation.
Topics: Adult; Cross-Sectional Studies; Emotions; Humans; Impulsive Behavior; Self Report; Suicidal Ideation
PubMed: 35912940
DOI: 10.1111/bjc.12383 -
Archives of Suicide Research : Official... 2023The present study seeks to determine differences in lifetime suicidal ideation, dispositional capability, acquired capability, and practical capability among those who...
OBJECTIVE
The present study seeks to determine differences in lifetime suicidal ideation, dispositional capability, acquired capability, and practical capability among those who have and have not served as first responders, and among subgroups of first responders.
METHODS
Data were collected as part of a large online ( = 3,500) study seeking to understand firearm ownership in the United States. Participants were recruited via Qualtrics Panels and were demographically matched to the 2010 US census. Binary logistic regressions and an exploratory multinomial logistic regression examined differences between first responders and non-first responders and among subgroups of first responders.
RESULTS
First responders reported more lifetime suicidal ideation and higher acquired, practical, and dispositional capability than did non-first responders. Findings indicated that first responders with and without military affiliation did not differ in terms of suicidal ideation or capability for suicide. Lastly, law enforcement officers (LEOs) reported more lifetime suicidal ideation than emergency medical technicians (EMTs). LEOs, EMTs, and firefighters did not differ in terms of capability for suicide.
DISCUSSION
The findings highlight that suicidal ideation and capability for suicide differ between first responders and non-first responders and among subgroups of first responders. The mechanisms driving the increased rates of suicidal ideation and capability among first responders are unknown; however, it is likely due to a combination of personal and occupational factors. Although not without its limitations, the present study provides an understanding of suicide risk among first responders.
Topics: Humans; United States; Suicidal Ideation; Suicide, Attempted; Risk Factors; Suicide; Firefighters
PubMed: 34699734
DOI: 10.1080/13811118.2021.1993397 -
The Clinical Journal of Pain Jul 2017Previous studies have demonstrated an association between migraine and major depressive disorder. However, relatively little is known about the relationship between... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Previous studies have demonstrated an association between migraine and major depressive disorder. However, relatively little is known about the relationship between suicidal ideation, with or without concurrent depression, and migraine.
OBJECTIVE
We conducted a systematic literature review to synthesize the available research focused on investigating the association of migraine with suicidal ideation.
METHODS
Relevant research papers were identified through searches of major electronic databases including PubMed, Embase (Elsevier), Web of Science (Thomson Reuters), PsycINFO (EBSCO), and Google Scholar. We performed a meta-analysis to estimate the pooled unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (95% CI) for the association between migraine and suicidal ideation extracted from each study.
RESULTS
A total of 148,977 participants in 6 studies were included in this analysis. Overall, findings from available studies documented elevated odds of suicidal ideation among individuals with migraines. In unadjusted models, the odds of suicidal ideation was 2.49-fold higher among individuals with migraine (OR, 2.49; 95% CI, 2.34-2.65) compared with those without migraine. In multivariate-adjusted models, the pooled adjusted OR of suicidal ideation was 1.31 (OR, 1.31; 95% CI, 1.10-1.55).
CONCLUSIONS
A meta-analysis of available studies suggests a modest positive association between migraine and suicidal ideation. Further studies allowing for a more comprehensive investigation of the association between migraine and the full range of suicidal behaviors are warranted. A larger and more robust evidence-base may be useful to inform the clinical screening and diagnoses of comorbid conditions in migraineurs.
Topics: Databases, Bibliographic; Humans; Migraine Disorders; Suicidal Ideation
PubMed: 27648590
DOI: 10.1097/AJP.0000000000000440 -
Journal of Community Psychology Jan 2022Sexual minorities (SMs) in the Church of Jesus Christ of Latter-day Saints (LDS) experience a number of unique risks related to their religious/spiritual and SM...
Sexual minorities (SMs) in the Church of Jesus Christ of Latter-day Saints (LDS) experience a number of unique risks related to their religious/spiritual and SM experience that may increase their likelihood of experiencing suicidal ideation (SI) and ultimately dying by suicide. However, it is unclear which aspects of these experiences are responsible for elevated SI. It is further unclear whether religiousness/spirituality and minority stress relate to SI similarly for active and nonactive/former LDS SMs. To address this gap, we examined data from 602 active and nonactive/former LDS SMs. Active and nonactive LDS SMs reported similar degrees of SI and minority stress but differing degrees of religiousness/spirituality with active LDS SMs reporting more religiousness/spirituality than nonactive/former LDS SMs. Several variables were associated with increased SI in both groups including positive religious coping, interpersonal religious struggles, internalized homonegativity, and concealment. Other variables were associated with decreased SI in both groups including resolving conflict between sexual and religious identities, family support, and friend support. Our results suggest that whether LDS SMs are active in their faith is an important factor to consider when understanding how religiousness/spirituality and minority stress relate to SI.
Topics: Adaptation, Psychological; Church of Jesus Christ of Latter-day Saints; Humans; Sexual Behavior; Sexual and Gender Minorities; Suicidal Ideation
PubMed: 34021914
DOI: 10.1002/jcop.22591 -
Anxiety, Stress, and Coping Sep 2023While much research exists linking stress and suicidality in cross-sectional paradigms, little is known regarding the longitudinal interplay of stress and suicidality...
While much research exists linking stress and suicidality in cross-sectional paradigms, little is known regarding the longitudinal interplay of stress and suicidality across time. In addition, less research exists on suicidal ideation - a transdiagnostic precursor to suicidal behavior. Two competing, though not mutually exclusive, explanations relate to , where stress causes suicidal ideation, and , where suicidal ideation causes stress. The present study examined 101 adults self-reporting symptoms of borderline personality disorder. Participants completed a self-report measure of suicidal ideation and a life stress interview in a three-wave design over the course of one year. Cross-lagged panel analyses were used to examine the longitudinal relationships between suicidal ideation and interpersonal/non-interpersonal chronic life stress, as well as dependent/interpersonal episodic life stress. Results supported chronic and episodic interpersonal stress generation for suicidal ideation, although not across all timepoints.
Topics: Adult; Humans; Suicidal Ideation; Cross-Sectional Studies; Risk Factors; Self Report; Stress, Psychological
PubMed: 36629459
DOI: 10.1080/10615806.2023.2165646 -
The American Journal of Geriatric... Jan 2017
Topics: Aging; Humans; Japan; Rural Population; Social Capital; Social Support; Suicidal Ideation
PubMed: 27889283
DOI: 10.1016/j.jagp.2016.11.001 -
Scientific Reports Mar 2022This study explored the differences in emotional memory between adolescents with and without suicidal ideation. Fifty adolescents with depression and suicidal ideation,...
This study explored the differences in emotional memory between adolescents with and without suicidal ideation. Fifty adolescents with depression and suicidal ideation, 36 with depression but no suicidal ideation, and 41 healthy controls rated the emotional valence of positive, neutral, and negative pictures. Then, the recognition of the images was evaluated 72 h later. Adolescents with suicidal ideation reported more negative emotional valence scores for positive and neutral pictures and were significantly less likely to recognize negative pictures than were those without suicidal ideation. The performance of adolescents with suicidal ideation on the negative picture recognition test was closely related to anxiety, depression severity, and intensity of suicidal ideation. The negative bias toward neutral stimuli and cognitive impairment may be important risk factors for adolescents with suicidal ideation. Improving emotional memory via targeted management approaches may help young people with suicidal ideation.
Topics: Adolescent; Anxiety; Anxiety Disorders; Depressive Disorder; Humans; Risk Factors; Suicidal Ideation
PubMed: 35361837
DOI: 10.1038/s41598-022-09459-4