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PloS One 2016Several intervention studies have suggested that vegetarian or vegan diets have clinical benefits, particularly in terms of glycemic control, in patients with type 2... (Randomized Controlled Trial)
Randomized Controlled Trial
OBJECTIVE
Several intervention studies have suggested that vegetarian or vegan diets have clinical benefits, particularly in terms of glycemic control, in patients with type 2 diabetes (T2D); however, no randomized controlled trial has been conducted in Asians who more commonly depend on plant-based foods, as compared to Western populations. Here, we aimed to compare the effect of a vegan diet and conventional diabetic diet on glycemic control among Korean individuals.
MATERIALS AND METHODS
Participants diagnosed with T2D were randomly assigned to follow either a vegan diet (excluding animal-based food including fish; n = 46) or a conventional diet recommended by the Korean Diabetes Association 2011 (n = 47) for 12 weeks. HbA1c levels were measured at weeks 0, 4, and 12, and the primary study endpoint was the change in HbA1c levels over 12 weeks.
RESULTS
The mean HbA1c levels at weeks 0, 4, and 12 were 7.7%, 7.2%, and 7.1% in the vegan group, and 7.4%, 7.2%, and 7.2% in the conventional group, respectively. Although both groups showed significant reductions in HbA1C levels, the reductions were larger in the vegan group than in the conventional group (-0.5% vs. -0.2%; p-for-interaction = 0.017). When only considering participants with high compliance, the difference in HbA1c level reduction between the groups was found to be larger (-0.9% vs. -0.3%). The beneficial effect of vegan diets was noted even after adjusting for changes in total energy intake or waist circumference over the 12 weeks.
CONCLUSION
Both diets led to reductions in HbA1c levels; however, glycemic control was better with the vegan diet than with the conventional diet. Thus, the dietary guidelines for patients with T2D should include a vegan diet for the better management and treatment. However, further studies are needed to evaluate the long-term effects of a vegan diet, and to identify potential explanations of the underlying mechanisms.
TRIAL REGISTRATION
CRiS KCT0001771.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Diet, Diabetic; Diet, Vegan; Female; Food Analysis; Glycated Hemoglobin; Humans; Male; Middle Aged; Oryza
PubMed: 27253526
DOI: 10.1371/journal.pone.0155918 -
Appetite Aug 2023Vegetarian and vegan (Veg*n) diets are increasingly popular in Western societies and an increasingly common topic of psychological research. Animal-free diets hold...
Vegetarian and vegan (Veg*n) diets are increasingly popular in Western societies and an increasingly common topic of psychological research. Animal-free diets hold considerable potential for helping curb the climate crisis and improving interspecies justice. This special issue presents recent contributions from research on the psychology of meat eating and veg*nism. To situate these articles in a broader context, we first establish the importance of studying veg*nism. We then review papers in this special issue, organized into themes of motivations and characteristics of veg*ns, attitudes towards veg*ns, attitudes toward meat and alternative proteins, intentions to eat meat or plant-based foods, consumption of meat or plant-based foods, and meat reduction interventions. We conclude with future directions for this blossoming field of study.
Topics: Animals; Humans; Diet, Vegetarian; Diet; Diet, Vegan; Vegetarians; Attitude; Meat
PubMed: 37121487
DOI: 10.1016/j.appet.2023.106582 -
Advances in Nutrition (Bethesda, Md.) Jun 2022Consumers are increasingly encouraged to consume more plant-based foods and lower their consumption of foods from animal origin. Concurrently, older adults are...
Consumers are increasingly encouraged to consume more plant-based foods and lower their consumption of foods from animal origin. Concurrently, older adults are recommended to consume an adequate amount of high-quality dietary protein for the prevention of age-related muscle loss. In the current Perspective article, we discuss why it may not be preferred to consume a vegan diet at an older age. Our perspective is based on the proposed lower bioavailability and functionality of proteins in a vegan diet due to the matrix of the whole-food protein sources, the lower essential amino acid (EAA) content, and specific EAA deficiencies in proteins derived from plant-based foods. We propose that a vegan diet increases the risk of an inadequate protein intake at an older age and that current strategies to improve the anabolic properties of plant-based foods are not feasible for many older adults. We provide recommendations for further research to substantiate the remaining knowledge gaps regarding the consequences of a vegan diet on skeletal muscle mass and strength at an older age.
Topics: Aged; Amino Acids, Essential; Animals; Diet, Vegan; Dietary Proteins; Eating; Humans; Muscle, Skeletal
PubMed: 35108354
DOI: 10.1093/advances/nmac009 -
Tidsskrift For Den Norske Laegeforening... May 2022
Topics: Breast Feeding; Diet; Diet, Vegan; Diet, Vegetarian; Female; Follow-Up Studies; Humans; Infant; Mothers; Pregnancy; Pregnant Women; Vegetarians
PubMed: 35510463
DOI: 10.4045/tidsskr.21.0847 -
The Veterinary Record Feb 2020
Topics: Animal Feed; Animal Welfare; Animals; Cats; Diet, Vegan; Dogs; Humans; Pets; United Kingdom; Vitamin D
PubMed: 32086397
DOI: 10.1136/vr.m663 -
International Journal of Environmental... Jan 2023Over the past few years, the number of people who have avoided animal products has been rising steadily. A plant-based diet is associated with a healthier lifestyle and... (Randomized Controlled Trial)
Randomized Controlled Trial
Over the past few years, the number of people who have avoided animal products has been rising steadily. A plant-based diet is associated with a healthier lifestyle and has positive effects on various diseases. More and more healthy active people and performance-orientated athletes are giving up animal products for various reasons, such as for an improved performance or faster regeneration. However, the data in this context are limited. This study aimed to obtain initial findings on the influence of a diet change to veganism on the performance of strength-trained individuals. For this study, a total of 15 omnivorous individuals were recruited. They documented their dietary food intakes over 16 weeks. Every four weeks, the strength performance was tested via a leg press and bench press. In the first 8 weeks, the participants maintained their omnivorous diet, followed by 8 weeks of a vegan dietary phase. In total, 10 subjects participated successfully, and their data were part of the statistical analyses. There was no difference in the absolute and relative strength performance for the leg and bench press after changing to a vegan diet. For the total calorie intake and carbohydrates, only a small treatment effect, but no time effect, was observed. However, for the protein intake, a time and group effect were detected. In addition, the relative protein intake decreased significantly and was lower than the current recommendations for athletes. The results demonstrate that a change to a vegan diet has no beneficial nor negative effect on the strength performance when the total calorie intake and carbohydrate content are covered in the first 8 weeks.
Topics: Animals; Humans; Pilot Projects; Diet; Diet, Vegan; Energy Intake; Vegans
PubMed: 36767221
DOI: 10.3390/ijerph20031856 -
World Review of Nutrition and Dietetics 2022
Review
Topics: Diet, Vegan; Diet, Vegetarian; Humans; Vegetarians
PubMed: 35240601
DOI: 10.1159/000516701 -
Nature Medicine Feb 2024Nutrition has broad impacts on all physiological processes. However, how nutrition affects human immunity remains largely unknown. Here we explored the impact of a...
Nutrition has broad impacts on all physiological processes. However, how nutrition affects human immunity remains largely unknown. Here we explored the impact of a dietary intervention on both immunity and the microbiota by performing a post hoc analysis of a clinical trial in which each of the 20 participants sequentially consumed vegan or ketogenic diets for 2 weeks ( NCT03878108 ). Using a multiomics approach including multidimensional flow cytometry, transcriptomic, proteomic, metabolomic and metagenomic datasets, we assessed the impact of each diet, and dietary switch, on host immunity and the microbiota. Our data revealed that overall, a ketogenic diet was associated with a significant upregulation of pathways and enrichment in cells associated with the adaptive immune system. In contrast, a vegan diet had a significant impact on the innate immune system, including upregulation of pathways associated with antiviral immunity. Both diets significantly and differentially impacted the microbiome and host-associated amino acid metabolism, with a strong downregulation of most microbial pathways following ketogenic diet compared with baseline and vegan diet. Despite the diversity of participants, we also observed a tightly connected network between datasets driven by compounds associated with amino acids, lipids and the immune system. Collectively, this work demonstrates that in diverse participants 2 weeks of controlled dietary intervention is sufficient to significantly and divergently impact host immunity, which could have implications for precision nutritional interventions. ClinicalTrials.gov registration: NCT03878108 .
Topics: Humans; Diet, Ketogenic; Diet, Vegan; Proteomics; Clinical Trials as Topic
PubMed: 38291301
DOI: 10.1038/s41591-023-02761-2 -
The Veterinary Record Aug 2018
Topics: Animals; Diet, Vegan; Feeding Behavior
PubMed: 30120186
DOI: 10.1136/vr.k3500 -
Critical Reviews in Food Science and... 2023In recent years, plant-based diets have experienced increasing popularity. However, plant-based diets may not always ensure an adequate supply of micronutrients, in... (Meta-Analysis)
Meta-Analysis
In recent years, plant-based diets have experienced increasing popularity. However, plant-based diets may not always ensure an adequate supply of micronutrients, in particular calcium. We performed a systematic review and meta-analysis of calcium intake in vegan and vegetarian diets as compared to omnivorous diets. We searched PubMed and Web of Science and identified 2,009 potentially relevant articles. Mean calcium intake values were pooled and standardized mean differences (SMD) and 95% confidence intervals (CI) were computed.We analyzed 74 studies, including 7,356 vegan, 51,940 vegetarian, and 107,581 omnivorous participants. Of these, dietary calcium intake was examined in 23 studies of vegans, 60 studies of vegetarians and 74 studies of omnivores. Vegans showed a substantially lower calcium intake than vegetarians (SMD = -0.57; 95%CI = -0.83 to -0.32; p = <0.0001) and omnivores (SMD = -0.70; 95%CI = -0.95 to -0.59; p < 0.0001), whereas no statistically significant difference in calcium intake was noted between vegetarians and omnivores (SMD = 0.07; 95%CI = -0.04 to 0.19; p = 0.1976). In conclusion, vegans show a lower calcium intake than vegetarians and omnivores. This finding emphasizes the need for vegans to monitor their calcium status.
Topics: Humans; Vegans; Calcium; Diet, Vegetarian; Diet; Diet, Vegan
PubMed: 38054787
DOI: 10.1080/10408398.2022.2084027