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Updates in Surgery Dec 2014Thoracic incisions are the portals of choice for accessing thoracic organs. There are instances, however, that more than one incision are required at the same or a later... (Review)
Review
Thoracic incisions are the portals of choice for accessing thoracic organs. There are instances, however, that more than one incision are required at the same or a later stage, in order to access other, thoracic or extrathoracic, organs for more complicated procedures. Then again, a single thoracic incision may offer more than adequate access to extrathoracic organs and in selected cases becomes valuable surgical approach to organs of the upper abdomen or the contralateral hemithorax. The experience with this technique is discussed.
Topics: Abdomen; Adrenal Glands; Diaphragm; Gastrointestinal Tract; Humans; Liver; Lung; Pancreas; Pleura; Spleen; Thoracotomy
PubMed: 25381550
DOI: 10.1007/s13304-014-0271-2 -
Journal of Clinical Ultrasound : JCU Jan 2022
Topics: Contrast Media; Humans; Lung; Pleura; Ultrasonography
PubMed: 35043444
DOI: 10.1002/jcu.23103 -
The Clinical Respiratory Journal Aug 2018Pleural infection is a condition commonly encountered by the respiratory physician. This review aims to provide the reader with an update on the most recent data... (Review)
Review
OBJECTIVES
Pleural infection is a condition commonly encountered by the respiratory physician. This review aims to provide the reader with an update on the most recent data regarding the epidemiology, microbiology, and the management of pleural infection.
DATA SOURCE
Medline was searched for articles related to pleural infection using the terms "pleural infection," "empyema," and "parapneumonic." The search was limited to the years 1997-2017. Only human studies and reports in English were included.
RESULTS
A rise in the incidence of pleural infection is seen worldwide. Despite the improvement in healthcare practices, the mortality from pleural infection remains high. The role of oral microflora in the etiology of pleural infection is firmly established. A concise review of the recent insights on the pathogenesis of pleural infections is presented. A particular focus is made on the role of tPA, DNAse and similar substances and their interaction with inflammatory cells and how this affects the pathogenesis and treatment of pleural infection.
CONCLUSION
Pleural infection is a common disease with significant morbidity and mortality, as well as a considerable economic burden. The role of medical management is expanding thanks to the widespread use of newer treatments.
Topics: Cost of Illness; Empyema, Pleural; Gastrointestinal Microbiome; Humans; Incidence; Pleura; Pleural Effusion; Thoracoscopy; Thrombolytic Therapy; Tomography, X-Ray Computed
PubMed: 30005142
DOI: 10.1111/crj.12941 -
Ceskoslovenska Patologie 2018Thoracic frozen section biopsies including lungs, pleura and mediastinum have crucial role in differential diagnosis of solitary lesions of the lungs and mediastinum.... (Review)
Review
Thoracic frozen section biopsies including lungs, pleura and mediastinum have crucial role in differential diagnosis of solitary lesions of the lungs and mediastinum. There is a significant difference in patient´s therapeutical management, if the patients suffer from lung primary malignant tumour, metastasis or non-malignant lesion. In this review, we summarize the usefulness of frozen section biopsies in thoracic surgery and provide 5-years of experiences with thoracic frozen section biopsies performed at the Department of Pathology and Molecular Medicine of Thomayer Hospital in Prague. Keywords: frozen section - lung - mediastinum.
Topics: Frozen Sections; Humans; Lung; Mediastinum; Pleura; Retrospective Studies
PubMed: 30445816
DOI: No ID Found -
European Journal of Cardio-thoracic... Aug 2022
Topics: Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Infant, Newborn; Pleura; Postoperative Period; Respiration, Artificial
PubMed: 35900190
DOI: 10.1093/ejcts/ezac398 -
Journal of Bronchology & Interventional... Apr 2023
Topics: Humans; Pleura; Specialization
PubMed: 37005379
DOI: 10.1097/LBR.0000000000000910 -
International Journal of Molecular... Mar 2020Malignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the... (Review)
Review
Malignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the pleural cavity, while the remaining cases initiate in the peritoneal cavity, in the pericardial cavity or on the tunica vaginalis. Usually, mesotheliomas grow in a diffuse pattern and tend to enclose and compress the organs in the various body cavities. Mesothelioma incidence is increasing worldwide and still today, the prognosis is very poor, with a reported median survival of approximately one year from presentation. Thus, the development of alternative and more effective therapies is currently an urgent requirement. The aim of this review article was to describe recent findings about the anti-cancer activity of curcumin and some of its derivatives on mesotheliomas. The potential clinical implications of these findings are discussed.
Topics: Antineoplastic Agents; Curcumin; Humans; Mesothelioma, Malignant; Phytochemicals; Pleura; Pleural Neoplasms; Prognosis
PubMed: 32155978
DOI: 10.3390/ijms21051839 -
Pleural biopsies in undiagnosed pleural effusions; Abrams vs image-guided vs thoracoscopic biopsies.Current Opinion in Pulmonary Medicine Jul 2016Pleural biopsies are often necessary if a pleural effusion remains undiagnosed after radiological imaging and pleural fluid analysis. There are many methods of obtaining... (Review)
Review
PURPOSE OF REVIEW
Pleural biopsies are often necessary if a pleural effusion remains undiagnosed after radiological imaging and pleural fluid analysis. There are many methods of obtaining pleural biopsies, including blind or image-guided procedures, closed-bevel or cutting-edge needles, and percutaneous or thoracoscopic approaches. This article will review recent research relating to these methods, aiming to provide an overview of the strengths and limitations of each technique.
RECENT FINDINGS
Historically pleural biopsies were undertaken using a blind closed 'Abrams' needle method. However, low diagnostic yields and high complication rates are seen with this technique compared with newer methods. Recent research compares image-guided, cutting-needle approaches to traditional Abrams biopsies, and evaluates the role of medical thoracoscopy in comparison to other techniques.
SUMMARY
Thoracoscopic biopsies are the gold standard for investigating pleural disease. However, this service is not universally available and may be unsuitable for some patients. Image-guided cutting-needle biopsies under computed tomography or ultrasound guidance have high diagnostic rates and are useful in a wide patient population. The main role of Abrams biopsies is in the diagnosis of tuberculous pleuritis in resource-poor settings.
Topics: Biopsy; Humans; Image-Guided Biopsy; Pleura; Pleural Effusion; Thoracoscopy
PubMed: 27055071
DOI: 10.1097/MCP.0000000000000258 -
Advances in Respiratory Medicine 2018Castleman's disease is a rare benign lymphoproliferative disorder of unknown etiology. The disease occurs in two clinical forms with different prognoses, treatments and... (Review)
Review
INTRODUCTION
Castleman's disease is a rare benign lymphoproliferative disorder of unknown etiology. The disease occurs in two clinical forms with different prognoses, treatments and symptoms: a unicentric form (UCD), which is solitary, localized, and a multicentric form characterized by generalized lymphadenopathy and systemic symptoms. This article aims to review the current literature to consolidate the evidence surrounding the curative potential of surgical treatment to the unicentric type.
MATERIAL AND METHODS
A systematic review of English-language literature was performed and databases (Medline, Pubmed, the Cochrane Database and grey literature) were searched to identify articles pertaining to the treatment of unicentric form of Castleman's disease. Each article was critiqued by two authors using a structured appraisal tool, and stratified according to the level of evidence.
RESULTS
After application of inclusion criteria, 14 studies were included. There were no prospective randomized control studies identified. One meta-analysis including 278 patients with UCD reported that resective surgery is safe and should be considered the gold standard for treatment. Seven retrospective studies enhance this standpoint. Radiotherapy (RT) has been used in six studies with controversial results.
CONCLUSIONS
We conclude that surgical resection appears to be the most effective treatment for Unicentric Castleman's Disease of the thoracic cavity. Radiotherapy can also achieve clinical response and cure in selected patients.
Topics: Castleman Disease; Humans; Pleura; Thoracic Cavity
PubMed: 29490420
DOI: 10.5603/ARM.2018.0008 -
The American Surgeon Jul 2023Endometriosis is a benign, inflammatory disease characterized by the presence of dysfunctional endometrial tissue outside the uterus. Typically confined to the pelvis,...
Endometriosis is a benign, inflammatory disease characterized by the presence of dysfunctional endometrial tissue outside the uterus. Typically confined to the pelvis, endometriosis is frequently associated with pain, dysmenorrhea, and infertility. Rarely, endometrial tissue has been documented to implant within the lung parenchyma and involve both parietal and visceral pleura of the thorax. Manifestations of thoracic endometriosis include catamenial pneumothorax, hemothorax, and hemoptysis. We present a case of thoracic endometriosis in a 43-year-old female who was found to have a loculated pleural effusion with an associated pleural nodule after gynecologic surgery. The patient underwent thoracotomy, decortication, and nodule excision. Pathology of the pleural nodule showed evidence of endometrial tissue within the parietal pleural. Thoracic endometriosis is a medical problem that is frequently undiagnosed and encountered by the practicing surgeon. Early diagnosis reduces both disease progression and late complications, allowing for early initiation of appropriate medical and surgical therapy.
Topics: Female; Humans; Adult; Endometriosis; Hemoptysis; Pleural Diseases; Pneumothorax; Pleura
PubMed: 36853850
DOI: 10.1177/00031348231161715